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Showing papers in "Journal of Nuclear Cardiology in 2003"


Journal ArticleDOI
TL;DR: Cardiac autonomic assessment using a combination of myocardial scintigraphic and neurophysiologic techniques may help select patients who would most benefit from an implantable defibrillator by identifying those at increased risk for potentially fatal arrhythmias.

165 citations


Journal ArticleDOI
TL;DR: Areas with a perfusion abnormality on stress SPECT had reduced CFR, and CFR was slightly, but significantly, lower in remote segments in patients with CAD compared with normal segments, in the areas without a perfusions abnormality and with coronary stenosis.

129 citations


Journal ArticleDOI
Isao Mitani1, Diwakar Jain1, Tammy M. Joska1, Barbara Burtness1, Barry L. Zaret1 
TL;DR: An incipient fall in LVEF detected on serial ERNA during doxorubicin therapy provides an appropriate and cost-effective approach for predicting and preventing impending CHF.

121 citations



Journal ArticleDOI
TL;DR: A consensus statement will examine the role of myocardial perfusion imaging studies in the diagnosis, risk assessment, and treatment of women with known or suspected coronary artery disease.

108 citations


Journal ArticleDOI
TL;DR: Publication supported by educational grants from: Amersham Health, Inc, and Siemens Medical Systems, Inc.

99 citations


Journal ArticleDOI
TL;DR: Patients with normal myocardial perfusion images in whom ST-segment depression develops during adenosine administration appear to be at increased risk for future cardiac events compared with similar patients without ECG evidence of ischemia.

99 citations


Journal ArticleDOI
TL;DR: This study demonstrated that an Agatston score of 400 is a logical threshold to initiate follow-up myocardial perfusion SPECT testing, and concluded that CAC screening with MDCT is justified for asymptomatic patients with 3 or more cardiac risk factors.

85 citations



Journal ArticleDOI
TL;DR: The finding of ischemic ECG changes with normal SPECT images during vasodilator infusion is uncommon, occurs primarily in older women, and is associated with a higher subsequent cardiac event rate than is customarily associated with normal images.

83 citations


Journal ArticleDOI
TL;DR: Large animal models of CHF are critical components in the effort to translate basic observations into beneficial clinical applications and may be used in conjunction with imaging modalities to elucidate the identification of cellular and extracellular alterations associated with LV failure.

Journal ArticleDOI
TL;DR: In patients referred for evaluation of myocardial perfusion, NCFs are unusual and require systematic and careful inspection of projection images for their detection, and may occasionally result in life-saving early cancer identification with Tl-201, TET, MIBI, or dual-isotope imaging.

Journal ArticleDOI
TL;DR: It is concluded that the annual mortality and cardiac event rate is less than 1% during 5-year follow-up after a normal exercise sestamibi study, and repeated testing would not be required unless there is a change in symptoms.

Journal ArticleDOI
TL;DR: The use of an ME collimator provides high quantitative accuracy and may enhance reliability in the evaluation of cardiac sympathetic nerve function and the effect of septal penetration is evaluated.

Journal ArticleDOI
TL;DR: The report should contain adequate information to support the medical necessity of the procedure and clarity and clinically relevant conclusions are encouraged.

Journal ArticleDOI
TL;DR: Accumulated basic and clinical evidence supports the use of inhibitors of the RAAS, including aldosterone antagonists, angiotensin-converting enzyme inhibitors, and angiotENSin receptor blockers, in treating hypertension, improving diabetic nephropathy, preventing or ameliorating congestive heart failure, and optimizing the prognosis after myocardial infarction.

Journal ArticleDOI
TL;DR: Myocardial ischemia, as assessed by myocardial perfusion imaging, is an important correlate of heart rate recovery, and there is a significant correlation between chronotropic variables during exercise testing andheart rate recovery 1 minute after exercise.

Journal ArticleDOI
TL;DR: Implementation of a comprehensive strategy for chest pain evaluation and triage reduced overall costs for patients with chest pain on presentation and acute MPI in the ED setting did not increase net cost.

Journal ArticleDOI
TL;DR: If as expected these new A2A agonists do not produce bronchoconstriction, then they can be used safely in virtually all patients, and clinical trials of these agents are now under way.

Journal ArticleDOI
TL;DR: Clinically, further studies are required to precisely define the prevalence of vascular calcification and its correlation with atherosclerotic disease, including risk factors for atherothrombotic disease such as smoking, diabetes, dyslipidemia, and sedentary lifestyle.

Journal ArticleDOI
TL;DR: The results indicate that filling of the stomach with a meal of solid food and liquid before rest acquisition may provide a high target-to-nontarget ratio and may reduce the frequency of intestinal activity of Tc-99m-labeled radiopharmaceuticals in myocardial perfusion imaging.

Journal ArticleDOI
TL;DR: A protocol combining 4 minutes of adenosine infusion with symptom-limited exercise was safe and well tolerated and resulted in a greater amount of myocardial ischemia detected on MPI while allowing for the assessment of functional capacity.


Journal ArticleDOI
TL;DR: In patients with known CAD with typical angina or with evidence of reversible ischemia despite taking medications, mental stress was very effective in inducing myocardial ischemies, as detected by sestamibi SPECT imaging, and good reproducibility was demonstrated.

Journal ArticleDOI
TL;DR: Assessment of Tl-201 myocardial SPECT yields only modest value to distinguish nonischemic dilated cardiomyopathy from ischemic cardiopathy in patients with chronic heart failure.

Journal ArticleDOI
TL;DR: Antianginal medication can alter both resting and hyperemic myocardial perfusion and might affect the ability to detect flow-limiting stenosis in patients undergoing perfusion imaging.

Journal ArticleDOI
TL;DR: Dr Verani was an able debater when assigned the position for advocating for stress radionuclide perfusion imaging against stress echocardiography, and engaged in these debates with substantial knowledge but always with a touch of humor.

Journal ArticleDOI
TL;DR: The occurrence of malignant VT in HCM may be associated with global cardiac sympathetic nerve activity rather than with the heterogeneity of this activity, as determined by the logistic multiple regression analysis.

Journal ArticleDOI
TL;DR: This review focuses on the use of adult bone marrowûderived stem cells for the treatment of ischemic cardiovascular disease and will contrast how far the authors have come in a short time with howfar they still need to go before stem cell therapy becomes routine in cardiovascular medicine.

Journal ArticleDOI
TL;DR: Patients with apical hypertrophic cardiomyopathy demonstrate a newly described “Solar Polar” map pattern at rest, as well as relative apical ischemia on the stress images even in the absence of CAD.