Showing papers in "Life Sciences in 1968"
••
255 citations
••
228 citations
••
TL;DR: Good evidence is obtained that there is a specific activation of the various NA nerve terminal systems of the brain and the spinal cord under the influence of immobilization stress.
199 citations
••
168 citations
••
TL;DR: Na+ is essential for the process that stores and accumulates NE and 5HT and that in synaptosomes the action of Na+ is inhibited by K+.
155 citations
••
TL;DR: A radiometric procedure for the estimation of cholinesterase activity was described which measures acetate-1-14C after the selective removal of the unhydrolyzed substrate, acetyl-1,14C-choline, as an insoluble reinecke salt.
118 citations
••
109 citations
••
TL;DR: Monilicolin A is active as a phytoalexin-inducing agent at very low concentrations (ED50 = 8 × 10−9 M) and its action appears to be specific for phaseollin-induction in as far as it has been assayed at present.
108 citations
••
102 citations
••
99 citations
••
••
••
••
TL;DR: A new class of tryptophan hydroxylase inhibitors, the 6-halotryptophans, are described, which cause a greater drop in serotonin levels than does p-C1P for an equimolar dose and may have a more complicated action in vivo than the simple competitive inhibition demonstrated in vitro.
••
TL;DR: The results indicate that lithium in therapeutic concentrations interferes with thyroid function probably by inhibiting release and/or synthesis of thyroid hormone.
••
••
••
TL;DR: It is demonstrated that antidepressants are effective in producing a muricidal block in male rats using a slightly different method and 5-HTP also shows some effectiveness in blocking muricidal behavior.
••
••
TL;DR: The optimum pH media on the viability of NEP two local isolate was determined and the effect of dose on mortality of termites for 24 hours was determined.
••
TL;DR: Brain noradrenalin concentration diurnal changes in cat hypothalamus and cervical spinal cord are studied, noting axon terminals of neurons change.
••
TL;DR: Angiotensin I was synthetized by the solid-phase method and tested in anesthetized rat, cat, rabbit and dog blood-pressure preparations and properties suggest that the lungs are the organs where the magnitude and rapidity of circulating angiotens in I conversion is of most physiological significance.
••
••
••
TL;DR: In general, the structure activity co-relations are similar to those found for insecticidal synergism, indicating that synergists and related compounds are probably of comparable toxicological significance to mammals, and there is an indication that some methylenedioxyphenyl compounds may exert a selective inhibitory action on microsomal hydroxylations.
••
••