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Showing papers in "The Journal of Thoracic and Cardiovascular Surgery in 2003"


Journal ArticleDOI
TL;DR: Continuous insulin infusion eliminates the incremental increase in in-hospital mortality after coronary artery bypass grafting associated with diabetes, and should become the standard of care for glycometabolic control in patients with diabetes undergoing coronary arteries bypass surgery.

1,095 citations


Journal ArticleDOI
TL;DR: Although mean scores on most outcomes were within normal limits, neurodevelopmental status in the cohort as a whole was below expectation in many respects, including academic achievement, fine motor function, visual-spatial skills, working memory, hypothesis generating and testing, sustained attention, and higher-order language skills.

609 citations



Journal ArticleDOI
TL;DR: The Cox maze III procedure has equivalent operative risk and long-term efficacy in patients undergoing both lone operations and concomitant procedures.

550 citations


Journal ArticleDOI
TL;DR: Deficient fibrillin-1 content in the vasculature of patients with bicuspid aortic valves might trigger matrix metalloproteinase production, leading to matrix disruption and dilatation in this disease.

429 citations


Journal ArticleDOI
TL;DR: Without delicate postoperative management to control pulmonary vascular resistance, the modified Norwood procedure using the right ventricle-pulmonary shunt provides a stable systemic circulation as well as adequate pulmonary blood flow.

428 citations


Journal ArticleDOI
TL;DR: In patients undergoing coronary artery bypass grafting surgery, the cyclooxygenase 2 inhibitor combination, parecoxib/valdecoxib, was effective for postoperative analgesia, however, the 14-day treatment regimen also was associated with an increased incidence of serious adverse events overall and sternal wound infections in particular.

397 citations


Journal ArticleDOI
TL;DR: Increased hemodilution severity during cardiopulmonary bypass was associated with worse perioperative vital organ dysfunction/morbidity and increased resource use, as well as greater short- and intermediate-term mortality.

394 citations



Journal ArticleDOI
TL;DR: The effect of duration of totalcirculatory arrest on later neurodevelopmental outcomes is nonlinear, with little influence at shorter durations and with steadily worsening outcomes after longer durations of circulatory arrest.

335 citations


Journal ArticleDOI
TL;DR: Daily home surveillance of arterial oxygen saturation according to pulse oximetry and weight selected patients at increased risk of interstage death, permitting timely intervention, primarily with early stage 2 palliation, and was associated with improved interstage survival.

Journal ArticleDOI
TL;DR: Fundoplication in lung transplant recipients with gastroesophageal reflux disease is associated with significant improvements in lung function, particularly if performed before the late stages of bronchiolitis obliterans syndrome.

Journal ArticleDOI
TL;DR: Until safer methods of ablation are developed, the use of IRAAF is recommended against the use in patients undergoing cardiac surgery, and a high degree of vigilance must be maintained for esophageal injury after IRAAF, particularly in patients with new neurologic deficits.

Journal ArticleDOI
TL;DR: In patients with peripheral T1 N0 M0 non-small cell lung cancer whose maximum tumor diameter was 2 cm or less, the outcome of limited pulmonary resection is comparable with that of pulmonary lobectomy.

Journal ArticleDOI
TL;DR: It is suggested that the higher incidence and greater severity of ischemic mitral regurgitation in patients with inferior compared with anterior myocardial infarction can be related to more severe geometric changes in the mitral valve apparatus with greater displacement of posterior papillary muscle caused by localized inferior basal left ventricular remodeling, which results in therapeutic implications for potential benefit of procedures.



Journal ArticleDOI
TL;DR: Aortic valve-sparing operations are safe in patients with the Marfan syndrome and may provide better clinical outcomes than aortic root replacement, and the size of the aneurysm often determines the feasibility of a valve- Sparing procedure is recommended.

Journal ArticleDOI
TL;DR: Embryonic stem cell transplantation significantly increased the survival rate in rats undergoing myocardial infarction during the experimental period of 32 weeks, and engrafted embryonic stem cells differentiated into cardiomyocytes in injured myocardium, caused an angiogenetic effect, and subsequently improved cardiac function during the 32-week observation period.

Journal ArticleDOI
TL;DR: Pulmonary resection of metastatic colorectal carcinoma is safe and results in long-term survival and the prethoracotomy carcinoembryonic antigen serum level is found to be an independent significant prognostic factor for survival.

Journal ArticleDOI
TL;DR: This pilot study demonstrates the feasibility of radiofrequency ablation for small peripheral lung tumors in patients with medical comorbidities, pulmonary compromise, or refusal of surgery, and indicates that larger tumors responded poorly.

Journal ArticleDOI
TL;DR: Competing risks analysis defines the prevalence of the various outcomes after Norwood operation and predicts improved outcomes with successful modification of controllable risk factors.

Journal ArticleDOI
TL;DR: This provocative article is not so much to enter the fray concerning which method of valvesparing aortic root replacement—Yacoub remodeling versus David reimplantation—is best for patients with the Marfan syndrome, but to clarify for the readership the key differences between the two procedures and how these operations have evolved.

Journal ArticleDOI
TL;DR: Lung transplantation is effective in improving the survival of selected patients affected by idiopathic pulmonary fibrosis, and multivariable analysis showed that lung transplantation reduced the risk of death by 75% after adjustment on potential confounding variables.

Journal ArticleDOI
TL;DR: Overall suboptimal results of the edge-to-edge technique when annuloplasty is not added to the repair are confirmed, particularly in view of minimally invasive and percutaneous approaches.

Journal ArticleDOI
TL;DR: Aortic prosthesis-patient size down to 1.1 cm(2)/m(2) or -3 Z did not reduce intermediate- or long-term survival after aortic valve replacement, and the increased early risk affected fewer than 1% of patients receiving bioprostheses but about 25% of those receiving mechanical devices.

Journal ArticleDOI
TL;DR: The relationship between the size of the aorta, in particular the cross-sectional area, and the patient’s height expressed as a ratio and the risk of aortic dissection has not been determined in patients with bicuspid aortsic valves.

Journal ArticleDOI
TL;DR: The World Health Organization histologic classification significantly correlated with the clinical stage, and tumor size, completeness of resection, histologic subtype, and stage predicted the prognosis of thymoma.

Journal ArticleDOI
TL;DR: In addition to soluble signaling molecules, direct cell-to-cell contact is obligatory in relaying the external cues of the microenvironment controlling the differentiation of adult stem cells to cardiomyocytes, indicating that human mesenchymal stem cells are plastic and can be reprogrammed into a cardiogenic lineage that may be used in cell-based therapy for treating heart failure.

Journal ArticleDOI
TL;DR: The 5-year interim results do not support the hypothesis that the radial artery has superior patency to or is associated with fewer clinical events than free right internal thoracic artery or saphenous vein grafts.