64-multislice detector computed tomography coronary angiography as potential alternative to conventional coronary angiography: a systematic review and meta-analysis.
Jawdat Abdulla,Steen Z. Abildstrom,Ole Gøtzsche,Erik Christensen,Lars Køber,Christian Torp-Pedersen +5 more
TLDR
The high diagnostic accuracy of 64-SCTA validates this non-invasive technique as a potential alternative to CCA in carefully selected populations suspected for coronary stenosis.Abstract:
Aims To evaluate the diagnostic accuracy of 64-slice multi-detector computed tomography coronary angiography (64-SCTA) compared with the standard reference conventional coronary angiography (CCA).
Methods and results Based on a systematic search, 27 studies including 1740 patients were eligible for meta-analyses. Nineteen studies examined native coronary arteries ( n = 1,251), four studies examined coronary artery by-pass grafts (CABG) ( n = 271), and five studies examined coronary stents ( n = 270). Overall 18 920 segments were assessable and 810 (4%) were unassessable. The prevalence of native coronary artery stenosis in per-segment (19 studies) and per-patients (13 studies) populations were 19 and 57.5% respectively. Accuracy tests with 95% confidence intervals comparing 64-SCTA vs. CCA showed that sensitivity, specificity, positive predictive and negative predictive values for native coronary arteries were 86(85–87), 96(95.5–96.5), 83, and 96.5% by per-segment analysis; 97.5(96–99), 91(87.5–94), 93, and 96.5% by per-patient analysis; 98.5(96–99.5), 96(93.5–97.5), 92 and 99% for CABGs; 80(70–88.5), 95(92–97), 80, and 95% for stent restenosis; and 87(86.5–88), 96(95.5–96.5), 83.5, and 97% by overall per-segment analysis.
Conclusion The high diagnostic accuracy of 64-SCTA validates this non-invasive technique as a potential alternative to CCA in carefully selected populations suspected for coronary stenosis.read more
Citations
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Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial.
Matthew J. Budoff,David A. Dowe,James G. Jollis,Michael J. Gitter,John Sutherland,Edward Halamert,Markus Scherer,Raye L. Bellinger,Arthur Martin,Robert Benton,Augustin Delago,James K. Min +11 more
TL;DR: In this prospective multicenter trial of chest pain patients without known CAD, 64-multidetector row CCTA possesses high diagnostic accuracy for detection of obstructive coronary stenosis at both thresholds of 50% and 70% stenosis.
Journal ArticleDOI
Noninvasive Coronary Artery Imaging Magnetic Resonance Angiography and Multidetector Computed Tomography Angiography: A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and Intervention, and the Councils on Clinical Cardiology and Cardiovascular Disease in the Young
David A. Bluemke,Stephan Achenbach,Matthew J. Budoff,Thomas C. Gerber,Bernard J. Gersh,L. David Hillis,W. Gregory Hundley,Warren J. Manning,Beth F. Printz,Matthias Stuber,Pamela K. Woodard +10 more
TL;DR: In this article, the coronary arterial lumen was computed using a single image of the coronary lumen, and the coronary artery lumen alone was computed with a single X-ray coronary angiogram.
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Cardiac Positron Emission Tomography/Computed Tomography Imaging Accurately Detects Anatomically and Functionally Significant Coronary Artery Disease
Sami Kajander,Esa Joutsiniemi,Markku Saraste,Mikko Pietilä,Heikki Ukkonen,Antti Saraste,Hannu Sipilä,Mika Teräs,Maija Mäki,Juhani Airaksinen,Jaana Hartiala,Juhani Knuuti +11 more
TL;DR: Cardiac hybrid PET/CT imaging allows accurate noninvasive detection of coronary artery disease in a symptomatic population and is feasible and can be performed routinely with <10 mSv in most patients.
Journal ArticleDOI
ICRP PUBLICATION 120: Radiological protection in cardiology.
C. Cousins,Donald L. Miller,Guglielmo Bernardi,Madan M. Rehani,Schofield P,Eliseo Vano,Andrew J. Einstein,Bernhard Geiger,Heintz P,R. Padovani,Kui-Hian Sim +10 more
TL;DR: Advice is provided to assist the cardiologist with justification procedures and optimisation of protection in cardiac CT studies, cardiac nuclear medicine studies, and fluoroscopically guided cardiac interventions, and quality assurance programmes for interventional fluoroscopy.
Journal ArticleDOI
Comparison of Coronary CT Angiography, SPECT, PET, and Hybrid Imaging for Diagnosis of Ischemic Heart Disease Determined by Fractional Flow Reserve
Ibrahim Danad,Pieter G. Raijmakers,Roel S. Driessen,Jonathon Leipsic,Rekha Raju,Christopher Naoum,Juhani Knuuti,Maija Mäki,Richard S. Underwood,James K. Min,James K. Min,Kimberly Elmore,Kimberly Elmore,W J Stuijfzand,Niels van Royen,Igor I. Tulevski,Aernout G. Somsen,Marc C. Huisman,Arthur van Lingen,Martijn W. Heymans,Peter M. van de Ven,Cornelis van Kuijk,Adriaan A. Lammertsma,Albert C. van Rossum,Paul Knaapen +24 more
TL;DR: This controlled clinical head-to-head comparative study revealed PET to exhibit the highest accuracy for diagnosis of myocardial ischemia and a combined anatomical and functional assessment does not add incremental diagnostic value but guides clinical decision-making in an unsalutary fashion.
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