Journal ArticleDOI
A chemotaxonomic division of Murraya based on the distribution of the alkaloids yuehchukene and girinimbine
Yun-Cheung Kong,Kin-Fai Cheng,Kam-Hung Ng,Paul Pui-Hay But,Qian-Li,Si-Xao Yu,Hung-Ta Chang,Richard C. Cambie,T. Kinoshita,Wei-song Kan,Peter G. Waterman +10 more
TLDR
An examination of the roots of Murraya for the presence of the dimeric indole yuehchukene has revealed a dichotomy in the genus between species producing this alkaloid and those producing the carbazole alkaloids girinimbine, with no apparent overlap between the two groups of species.About:
This article is published in Biochemical Systematics and Ecology.The article was published on 1986-10-02. It has received 43 citations till now. The article focuses on the topics: Girinimbine & Yuehchukene.read more
Citations
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Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
Journal ArticleDOI
A molecular phylogeny of the orange subfamily(Rutaceae: Aurantioideae) using nine cpDNA sequences
Randall J. Bayer,David J. Mabberley,Cynthia C. Morton,Cathy H. Miller,Ish K. Sharma,Bernard E. Pfeil,Sarah Meghan Rich,Roberta Hitchcock,Steve Sykes +8 more
TL;DR: The breeding of new, high-quality citrus cultivars depends on dependable information about the relationships of taxa within the tribe Citreae; therefore, it is important to have a well-supported phylogeny of the relationships between species not only to advance breeding strategies, but also to advance conservation strategies for the wild taxa.
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Phylogenetic Analyses of Aurantioideae (Rutaceae) Based on Non‐Coding Plastid DNA Sequences and Phytochemical Features
TL;DR: Molecular, chemical, and other data show that none of the subtribes recognized within Aurantioideae reflect phylogenetic relationships, and the monophyly of several larger genera in both tribes is supported by relatively high bootstrap percentages and specific chemical profiles for e.g., Clausena, Micromelum, Glycosmis and Atalantia.
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The mu opioid receptor: A new target for cancer therapy?
TL;DR: In this paper, the authors present preclinical and clinical data that support their hypothesis that the mu opioid receptor is a potential target for cancer therapy because of its plausible role in tumor progression, and they also propose the hypothesis that peripheral opioid antagonists such as methylnaltrexone, which reverses the peripheral effects of mu opioids but maintains centrally mediated analgesia and is approved by the US Food and Drug Administration for the treatment of opioid-induced constipation, can be used to target the Mu opioid receptor.
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Seasonal variations of carbazole alkaloids in Murraya euchrestifolia
TL;DR: In this article, four new carbazole alkaloids, murrayamines F-H and euchrestifoline, were isolated from the leaves of Murraya euchsrestrifolia in May.
References
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Yuehchukene: a novel indole alkaloid with anti-implantation activity
TL;DR: Yuehchukene, a novel dimeric indole alkaloid with potent anti-implantation activity has been isolated from the roots of Murraya paniculata and identified as a racemic mixture of 6β-(3′-indolyl)-7α,7β,9-trimethyl-6aβ7,8,10aβ-tetrahydroindeno[2,1-b]indole (1) and its enantiomer.
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Yuehchukene, a Novel Anti-implantation Indole Alkaloid from Murraya paniculata.
Yun Cheung Kong,K. H. Ng,K. H. Wat,A. Wong,I. F. Saxena,K. F. Cheng,P. P. H. But,H. T. Chang +7 more
TL;DR: Yuehchukene, a novel dimeric indole alkaloid from the roots of MURRAY A PANICULATA has potent anti-implantation activity in rats at 3 mg/kg P. O. dosing on pregnancy day 2.
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On the structures of girinimbine, mahanimbine, isomahanimbine, koenimbidine and murrayacine
TL;DR: The isolation of mahanimbine, girinimbine and two new carbazole alkaloids isomahanim bine and koenimbidine from the leaves and roots of Murraya koenigii Spreng is reported.
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Biomimetic synthesis of yeuhchukene
TL;DR: In this paper, a potential antifertility agent was synthesized by Diels-Alder cyclization of 3-isoprenylindole (3-ISOPRENYLINDO).