Journal ArticleDOI
A Conducting Polymer Nanojunction Sensor for Glucose Detection
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TLDR
In this paper, a glucose sensor using conducting polymer/enzyme nano-junctions is presented, where each nano-junction is formed by bridging a pair of nanoelectrodes separated with a small gap (20−60 nm) with polyaniline/glucose oxidase.Abstract:
This paper presents a glucose sensor using conducting polymer/enzyme nanojunctions and demonstrates that unique features can arise when shrinking a sensor to the nanometer scale. Each nanojunction is formed by bridging a pair of nanoelectrodes separated with a small gap (20−60 nm) with polyaniline/glucose oxidase. The signal transduction mechanism of the sensor is based on the change in the nanojunction conductance as a result of glucose oxidation induced change in the polymer redox state. Due to the small size of the nanojunction sensor, the enzyme is regenerated naturally without the need of redox mediators, which consumes minimal amount of oxygen and at the same time gives very fast response (<200 ms). These features make the nanojunction sensor potentially useful for in vivo detection of glucose.read more
Citations
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Electrochemical Glucose Biosensors
TL;DR: The major factors that play a role in the development of clinically accurate in-vivo glucose sensors include issues related to biocompatibility, miniaturization, long-term stability of the enzyme and transducer, oxygen deficit, short stabilization times, in- vivo calibration, baseline drift, safety, and convenience.
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Graphene oxide: intrinsic peroxidase catalytic activity and its application to glucose detection.
TL;DR: A simple, cheap, and highly sensitive and selective colorimetric method for glucose detection has been developed and will facilitate the utilization of GO-COOH intrinsic peroxidase activity in medical diagnostics and biotechnology.
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Hierarchical nanostructured conducting polymer hydrogel with high electrochemical activity
Lijia Pan,Guihua Yu,Dongyuan Zhai,Hye Ryoung Lee,Wenting Zhao,Nian Liu,Huiliang Wang,Benjamin C. K. Tee,Yi Shi,Yi Cui,Zhenan Bao +10 more
TL;DR: The scalable synthesis and excellent electrode performance of the PAni hydrogel make it an attractive candidate for bioelectronics and future-generation energy storage electrodes.
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Nanomaterial-based electrochemical biosensors
TL;DR: New nanoparticle-based signal amplification and coding strategies for bioaffinity assays are discussed, along with carbon-nanotube molecular wires for achieving efficient electrical communication with redox enzyme and nanowire-based label-free DNA sensors.
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A comprehensive review of glucose biosensors based on nanostructured metal-oxides.
TL;DR: This article concentrates mainly on the development of different nanostructured metal-oxide based glucose biosensors with high sensitivity, fast response times, and stability for the determination of glucose by electrochemical oxidation.
References
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Journal ArticleDOI
Nanotube molecular wires as chemical sensors
Jing Kong,Nathan R. Franklin,Chongwu Zhou,Michael Chapline,Shu Peng,Kyeongjae Cho,Hongjie Dai +6 more
TL;DR: The nanotubes sensors exhibit a fast response and a substantially higher sensitivity than that of existing solid-state sensors at room temperature and the mechanisms of molecular sensing with nanotube molecular wires are investigated.
Journal ArticleDOI
Nanowire Nanosensors for Highly Sensitive and Selective Detection of Biological and Chemical Species
TL;DR: The small size and capability of these semiconductor nanowires for sensitive, label-free, real-time detection of a wide range of chemical and biological species could be exploited in array-based screening and in vivo diagnostics.
Journal ArticleDOI
Direct ultrasensitive electrical detection of DNA and DNA sequence variations using nanowire nanosensors
TL;DR: Two-terminal silicon nanowire electronic devices that function as ultrasensitive and selective detectors of DNA are reported that show that detection can be carried out to at least the tens of femtomolar range.
Journal ArticleDOI
Hydrogen Sensors and Switches from Electrodeposited Palladium Mesowire Arrays
TL;DR: Hydrogen sensors and hydrogen-activated switches were fabricated from arrays of mesoscopic palladium wires fabricated by electrodeposition onto graphite surfaces and transferred onto a cyanoacrylate film.
Journal ArticleDOI
Glucose Biosensors Based on Carbon Nanotube Nanoelectrode Ensembles
TL;DR: In this article, a glucose biosensors based on carbon nanotube (CNT) nanoelectrode ensembles (NEEs) was developed for the selective detection of glucose.