Open AccessJournal Article
A morphologic study of rabbit bronchial lymphoid aggregates and lymphoepithelium
TLDR
Ultrastructural studies of the rabbit bronchial mucosa revealed that the bronchus-associated lymphoid aggregates could be distinguished from the surrounding tissue, since they were covered with epithelial cells possessing microvilli but not cilia.About:
This article is published in Laboratory Investigation.The article was published on 1976-10-01 and is currently open access. It has received 68 citations till now. The article focuses on the topics: Ultrastructure & Epithelium.read more
Citations
More filters
Journal ArticleDOI
Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity.
Juan Moyron-Quiroz,Javier Rangel-Moreno,Kim Kusser,Louise Hartson,Frank Sprague,Stephen Goodrich,David L. Woodland,Frances E. Lund,Troy D. Randall +8 more
TL;DR: It is shown that mice lacking spleen, lymph nodes and Peyer's patches generate unexpectedly robust primary B- and T-cell responses to influenza, which seem to be initiated at sites of induced BALT (iBALT), which functions as an inducible secondary lymphoid tissue for respiratory immune responses.
Journal ArticleDOI
Chitosan-based delivery systems for protein therapeutics and antigens
TL;DR: This review provides an overview of chitosan-based polymers for preparation of both therapeutic peptides/protein and antigen formulations and their applications in protein and antigen delivery through parenteral and mucosal administrations.
Journal ArticleDOI
Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis
Javier Rangel-Moreno,Louise Hartson,Carmen Navarro,Miguel Gaxiola,Moisés Selman,Troy D. Randall +5 more
TL;DR: It is shown that while B cell follicles containing germinal centers and follicular dendritic cells can be found in the lungs of patients suffering from multiple diseases, well-developed iBALT is most prevalent in patients with pulmonary complications of RA and Sjögren syndrome.
Journal ArticleDOI
The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions.
TL;DR: It is proposed that GTL belong to a special class of T lymphocytes, related to the immune defenses of the mucosal systems in general, and capable of acting as progenitors of mucosal mast cells.
Journal ArticleDOI
Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans?
Reinhard Pabst,Ilse Gehrke +1 more
TL;DR: BALT seems to be a lymphoid structure which is not present in all the species studied but can develop in the lung after stimulation, in contrast to lymphoid organs, such as lymph nodes or Peyer's patches, which can always be found.