Journal ArticleDOI
A prospective study of the impact of weight loss and the systemic inflammatory response on quality of life in patients with inoperable non-small cell lung cancer.
Hazel R. Scott,Donald C. McMillan,Duncan J.F Brown,L M Forrest,Colin S. McArdle,Robert Milroy +5 more
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TLDR
The results of the present study indicate that both weight loss and the systemic inflammatory response impact on different aspects of quality of life.About:
This article is published in Lung Cancer.The article was published on 2003-06-01. It has received 74 citations till now. The article focuses on the topics: Weight loss & Performance status.read more
Citations
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Journal ArticleDOI
Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer.
TL;DR: A score based on the combination of the systemic inflammatory response and albumin hazards ratio (HR) was comparable in prognostic value to that based on stage and performance status in patients with inoperable non-small-cell lung cancer.
Journal ArticleDOI
Role of nutritional status in predicting quality of life outcomes in cancer – a systematic review of the epidemiological literature
TL;DR: It is recommended that more providers implement the American Society of Parenteral and Enteral Nutrition (ASPEN) guidelines for oncology patients, which includes nutritional screening, nutritional assessment and intervention as appropriate.
Journal ArticleDOI
The correlation between fatigue, physical function, the systemic inflammatory response, and psychological distress in patients with advanced lung cancer.
TL;DR: Functional disability is reported frequently in fatigued cancer patients, but little is known about the correlation between fatigue and objective physical function.
Journal ArticleDOI
Cancer cachexia--pathophysiology and management.
TL;DR: The best treatment of the cachectic syndrome is a multifactorial approach, and health care providers must also recognize the psychosocial and biomedical impact cachexia can have.
Journal ArticleDOI
Cancer Cachexia: Mechanisms and Clinical Implications
TL;DR: Cachexia is a multifactorial process of skeletal muscle and adipose tissue atrophy resulting in progressive weight loss as mentioned in this paper, which is associated with poor quality of life, poor physical function, and poor prognosis in cancer patients.
References
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Journal ArticleDOI
The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
Neil K. Aaronson,Sam H Ahmedzai,Bengt Bergman,Monika Bullinger,Ann Cull,Nicole Duez,Antonio Filiberti,Henning Flechtner,Stewart B. Fleishman,Johanna C. J. M. de Haes,Stein Kaasa,M. Klee,David Osoba,Darius Razavi,Peter B. Rofe,Simon Schraub,Kommer C. A. Sneeuw,Marianne Sullivan,Fumikazu Takeda +18 more
TL;DR: The reliability and validity of the EORTC QLQ-C30 questionnaire were highly consistent across the three language-cultural groups studied: patients from English-speaking countries, Northern Europe, and Southern Europe.
Journal ArticleDOI
A new international staging system for lung cancer
TL;DR: The International Staging System for Lung Cancer provides for classification of six levels of disease extent in five stage groups that relate to patient management and prognosis and can be readily applied in a broad spectrum of clinical and teaching environments.
Journal ArticleDOI
The Karnofsky Performance Status Scale. An examination of its reliability and validity in a research setting.
TL;DR: The utility of the Karnofsky Performance Status Scale as a valuable research tool when employed by trained observers is suggested and the relationship of the KPS to longevity in a population of terminal cancer patients documents its predictive validity.
Journal ArticleDOI
Albumin concentrations are primarily determined by the body cell mass and the systemic inflammatory response in cancer patients with weight loss.
Donald C. McMillan,Walter S. Watson,Patricia O'Gorman,Tom Preston,Hazel R. Scott,Colin S. McArdle +5 more
TL;DR: The interrelationship between albumin, body cell mass, and the inflammatory response is consistent with the concept that the presence of an ongoing inflammatory response contributes to the progressive loss of these vital protein components of the body and the subsequent death of patients with advanced cancer.
Journal ArticleDOI
Long-term survivors in metastatic non-small-cell lung cancer: an Eastern Cooperative Oncology Group Study.
TL;DR: A detailed chart review of 32 2-year survivors and 32 matched controls demonstrated that maintenance or improvement of performance status and maintenance of serum albumin levels at 3 months from the initiation of treatment were both important predictors of longer survival.
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