Journal ArticleDOI
Accuracy of endoscopic ultrasound elastography used for differential diagnosis of focal pancreatic masses: a multicenter study
Adrian Saftoiu,Peter Vilmann,Florin Gorunescu,Jan Janssen,Michael Hocke,Michael Larsen,Julio Iglesias-Garcia,Paolo Giorgio Arcidiacono,Uwe Will,Marc Giovannini,Christoph F. Dietrich,Roald Flesland Havre,Cristian Gheorghe,Colin J. McKay,Dan Ionuţ Gheonea,Tudorel Ciurea +15 more
TLDR
The value of quantitative analysis of EUS elastography recordings was proven by good reproducibility of the videos, as well as good parameters of the AUROC analysis.Abstract:
Background and study aims Endoscopic ultrasound (EUS) elastography represents a new imaging procedure that might characterize the differences of hardness and strain between diseased tissue and normal tissue. The aim of this study was to assess the efficiency of EUS elastography for the differentiation of focal masses in chronic pancreatitis and pancreatic cancer. Patients and methods The study group comprised 258 patients with focal pancreatic masses included prospectively at 13 participating centers. Qualitative analysis of the diagnoses made by two expert doctors using all recorded video clips was performed in order to test the interobserver variability. A post-processing software analysis was used to examine the EUS elastography videos by calculating average-hue histograms of individual elastography images. The quantitative information was used to calculate intra-observer variability and the accuracy of the method. Results Qualitative analysis of the recorded videos revealed a kappa value of 0.72. Intra-observer variability analysis revealed that the single measure intraclass correlation ranged between 0.86 and 0.94. The average-hue histogram analysis of the data indicated a sensitivity of 93.4 %, a specificity of 66.0 %, a positive predictive value of 92.5 %, a negative predictive value of 68.9 %, and an overall accuracy of 85.4 %, based on a cut-off value of 175. Area under the receiver operating characteristic curve (AUROC) was 0.854 ( P Conclusion The value of quantitative analysis of EUS elastography recordings was proven by good reproducibility of the videos, as well as good parameters of the AUROC analysis. (Clinical Trials.gov identifier: CT00909103).read more
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Journal ArticleDOI
EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography.Part 2: Clinical Applications
David O. Cosgrove,Fabio Piscaglia,Jeffrey C. Bamber,Jörg Bojunga,Jean Michel Correas,Odd Helge Gilja,Andrea Klauser,Ioan Sporea,Fabrizio Calliada,Cantisani,Mirko D'Onofrio,E. E Drakonaki,Mathias Fink,Mireen Friedrich-Rust,Jeremie Fromageau,Roald Flesland Havre,Christian Jenssen,R Ohlinger,Adrian Saftoiu,F Schaefer,Christoph F. Dietrich +20 more
TL;DR: The clinical part of these Guidelines and Recommendations produced under the auspices of the European Federation of Societies for Ultrasound in Medicine and Biology EFSUMB assesses the clinically used applications of all forms of elastography, stressing the evidence from meta-analyses and giving practical advice for their uses and interpretation.
Journal ArticleDOI
The EFSUMB Guidelines and Recommendations for the Clinical Practice of Elastography in Non-Hepatic Applications: Update 2018
Adrian Saftoiu,Odd Helge Gilja,Paul S. Sidhu,Christoph F. Dietrich,Vito Cantisani,Dominique Amy,Michael Bachmann-Nielsen,Flaviu Bob,Jörg Bojunga,Marko Brock,Fabrizio Calliada,Dirk-André Clevert,Jean-Michel Correas,Mirko D'Onofrio,Caroline Ewertsen,André Farrokh,Daniela Fodor,Pietro Fusaroli,Roald Flesland Havre,Michael Hocke,Andre Ignee,Christian Jenssen,Andrea Klauser,Christian Kollmann,Maija Radzina,Kumar V. Ramnarine,Luca Maria Sconfienza,Carolina M Solomon,Ioan Sporea,Horia Ștefănescu,Mickael Tanter,Peter Vilmann +31 more
TL;DR: This manuscript describes the use of ultrasound elastography, with the exception of liver applications, and represents an update of the 2013 EFSUMB (European Federation of Societies for Ultrasound in Medicine and Biology) Guidelines and Recommendations on the clinical use ofElastography.
Journal ArticleDOI
Efficacy of an Artificial Neural Network–Based Approach to Endoscopic Ultrasound Elastography in Diagnosis of Focal Pancreatic Masses
Adrian Saftoiu,Adrian Saftoiu,Peter Vilmann,Florin Gorunescu,Jan Janssen,Michael Hocke,Michael Larsen,Julio Iglesias Garcia,Paolo Giorgio Arcidiacono,Uwe Will,Marc Giovannini,Cristoph F. Dietrich,Roald Flesland Havre,Cristian Gheorghe,Colin J. McKay,Dan Ionuţ Gheonea,Tudorel Ciurea +16 more
TL;DR: The accuracy of real-time EUS elastography in focal pancreatic lesions using computer-aided diagnosis by artificial neural network analysis is assessed, providing fast and accurate diagnoses.
Journal ArticleDOI
New ultrasound techniques for lymph node evaluation
TL;DR: Current literature regarding evaluation of lymphadenopathy by new and innovative US techniques is reviewed, showing potential to improve the accuracy of US for the differential diagnosis of benign and malignant lymph nodes.
Journal ArticleDOI
EUS elastography for diagnosis of solid pancreatic masses: a meta-analysis
TL;DR: EUS elastography is a reliable technique for the characterization of solid pancreatic masses and may be a useful complementary tool for EUS-guided FNA.
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