Journal ArticleDOI
Action potential recording from dielectrophoretically positioned neurons inside micro-wells of a planar microelectrode array
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TLDR
Spontaneous and evoked action potentials from trapped neurons were successfully recorded using a 16-channel acquisition/stimulation unit and this system provides a fast, effective and inexpensive way to assemble neural grids consisting of contacts between electrodes and single neurons.About:
This article is published in Journal of Neuroscience Methods.The article was published on 2009-09-15. It has received 30 citations till now. The article focuses on the topics: Multielectrode array & Dielectrophoresis.read more
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Review Article—Dielectrophoresis: Status of the theory, technology, and applications
TL;DR: Current trends suggest that the theory and technology have matured sufficiently for most effort to now be directed towards applying DEP to unmet needs in such areas as biosensors, cell therapeutics, drug discovery, medical diagnostics, microfluidics, nanoassembly, and particle filtration.
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Cellular dielectrophoresis: applications to the characterization, manipulation, separation and patterning of cells.
TL;DR: There is need for a critical report to integrate the many new features ofDEP for cellular applications, and a review of the basic theory and current applications of DEP, specifically for cells is presented.
Dielectrophoretic cell separation and gene expression profiling on microelectronic chip arrays
TL;DR: The presented approach of using microelectronic chip arrays for both cell separation and gene expression profiling provides a great potential for accurate genetic analysis of specific cell subpopulations in heterogeneous samples.
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Cell adhesion promotion strategies for signal transduction enhancement in microelectrode array in vitro electrophysiology: An introductory overview and critical discussion
TL;DR: This will lead to the discussion of popular strategies for enhancing and steering interfacial interactions at the bio-hardware boundary with particular focus on MEA substrates, and include a critical treatment of open issues with respect to the origin and shape of extracellularly recorded signals and their modulation by cell-culture-inherent events.
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Dielectrophoretic Manipulation and Separation of Microparticles Using Microarray Dot Electrodes
TL;DR: The findings confirm the capability of the proposed device to rapidly and efficiently manipulate and separate microparticles of various dimensions, utilizing positive and negative dielectrophoresis (DEP) effects.
References
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Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
TL;DR: High survival was achieved with osmolarity lower than found in Dulbecco's Modified Eagle's Medium (DMEM), and by reducing cysteine and glutamine concentrations and by the elimination of toxic ferrnous sulphate found in DME/F12, and Neurobasal is a new medium that incorporates modifications to DMEM.
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The Motion and Precipitation of Suspensoids in Divergent Electric Fields
TL;DR: In this article, it was shown that the phenomena of dielectrophoresis and dielectro-precipitation can be observed under rather ideal conditions, though it is ordinarily often difficult to do so because of the presence of the more easily produced electrophoreis or ion-type migration of charged particles.
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Biocompatibility and biofouling of MEMS drug delivery devices
Gabriela Voskerician,Matthew S. Shive,Rebecca S. Shawgo,Horst A. von Recum,James M. Anderson,Michael J. Cima,Robert Langer +6 more
TL;DR: These analyses identified the MEMS component materials, gold, silicon nitride, silicon dioxide, SU-8(TM), and silicon as biocompatible, with gold and silicon showing reduced biofouling.
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Recording action potentials from cultured neurons with extracellular microcircuit electrodes.
TL;DR: Dissociated cell cultures of neurons from neonatal rat superior cervical ganglia have been grown in specially prepared dishes, the bottoms of which consist of glass coverslips on which thin-film microcircuits have been deposited, suitable for passing the current required for extracellular stimulation.
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The use of neuronal networks on multielectrode arrays as biosensors
TL;DR: This work presents strategies for the expression of novel supersensitivities to foreign molecules via genetic engineering that involves the grafting of ligand binding cDNA onto truncated native receptor DNA and the subsequent expression of such chimeric receptors.