Journal ArticleDOI
Addition of Allylindium Reagents to Aldehydes Substituted at Cα or Cβ with Heteroatomic Functional Groups. Analysis of the Modulation in Diastereoselectivity Attainable in Aqueous, Organic, and Mixed Solvent Systems
Leo A. Paquette,Thomas M. Mitzel +1 more
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TLDR
In this paper, the stereochemical course of indium-promoted allylations to α- and β-oxy aldehydes has been investigated in solvents ranging from anhydrous THF to pure H2O.Abstract:
The stereochemical course of indium-promoted allylations to α- and β-oxy aldehydes has been investigated in solvents ranging from anhydrous THF to pure H2O. The free hydroxyl derivatives react with...read more
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Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
TL;DR: Reaction of R,â-Unsaturated Carbonyl Compounds 3127: Reaction of R-UnSaturated Carbonies 3127 7.1.6.
Journal ArticleDOI
Organic syntheses using indium-mediated and catalyzed reactions in aqueous media
Chao-Jun Li,Tak Hang Chan +1 more
TL;DR: Indium-Mediated Barbier-type reactions as discussed by the authors have been used for a variety of purposes, such as the synthesis of sialic acids and carbohydrate homologations.
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Diastereoselective allylation of carbonyl compounds and imines: application to the synthesis of natural products.
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, as to provide real-time information about concrete mechanical properties such as E-modulus and compressive strength.
References
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Journal ArticleDOI
Protection of hydroxyl groups as tert-butyldimethylsilyl derivatives
E. J. Corey,A. Venkateswarlu +1 more
TL;DR: In this paper, the authors describe a group of ethers calleddimethyl-tert-butylsilyl, which are stable in water or alcohol bases under normal conditions and also stable to hydrogenolysis and mild chemical reduction.
Journal ArticleDOI
Organic reactions in aqueous media - with a focus on carbon-carbon bond formation
TL;DR: In the last decade, there has been increasing recognition that organic reactions carried out in aqueous media may offer advantages over those occurring in organic solvents as discussed by the authors, which is the essence of organic synthesis.
Journal ArticleDOI
Directed reduction of .beta.-hydroxy ketones employing tetramethylammonium triacetoxyborohydride
TL;DR: The mild reducing agent tetramethylammonium triacetoxyborohydride reduces acyclic P-hydroxy ketones to their corresponding anti diols with high diastereoselectivity as mentioned in this paper.
Journal ArticleDOI
Geometrical reaction coordinates. II. Nucleophilic addition to a carbonyl group
Journal ArticleDOI
Stereochemistry of reaction paths at carbonyl centres
TL;DR: In this article, the reaction paths found by different methods for different nucleophiles show some striking similarities that appear to be characteristic for the reaction type, and the results of recent experimental and theoretical studies of nucleophilic addition to carbonyl groups are described.
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Indium-Mediated Organometallic Reactions in Aqueous Media: The Nature of the Allylindium Intermediate
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