Agents that increase the permeability of the outer membrane.
TLDR
Chelators (such as EDTA, nitrilotriacetic acid, and sodium hexametaphosphate), which disintegrate the outer membrane by removing Mg2+ and Ca2+, are effective and valuable permeabilizers.About:
This article is published in Microbiological Research.The article was published on 1992-09-01 and is currently open access. It has received 1718 citations till now. The article focuses on the topics: Bacterial outer membrane & Gram-negative bacteria.read more
Citations
More filters
Journal ArticleDOI
Essential oils: their antibacterial properties and potential applications in foods--a review.
TL;DR: In vitro studies have demonstrated antibacterial activity of essential oils (EOs) against Listeria monocytogenes, Salmonella typhimurium, Escherichia coli O157:H7, Shigella dysenteria, Bacillus cereus and Staphylococcus aureus at levels between 0.2 and 10 microl ml(-1).
Journal ArticleDOI
Antiseptics and Disinfectants: Activity, Action, and Resistance
TL;DR: Known mechanisms of microbial resistance (both intrinsic and acquired) to biocides are reviewed, with emphasis on the clinical implications of these reports.
Journal ArticleDOI
Molecular Basis of Bacterial Outer Membrane Permeability Revisited
TL;DR: This review summarizes the development in the field since the previous review and begins to understand how this bilayer of the outer membrane can retard the entry of lipophilic compounds, owing to increasing knowledge about the chemistry of lipopolysaccharide from diverse organisms and the way in which lipopoly Saccharide structure is modified by environmental conditions.
Journal ArticleDOI
Characterization of the action of selected essential oil components on gram-negative bacteria
Ilkka M. Helander,Hanna-Leena Alakomi,Kyösti Latva-Kala,Tiina Mattila-Sandholm,Irene E. Pol,Eddy J. Smid,Leon G.M. Gorris +6 more
TL;DR: Of the tested components, carvacrol and thymol decreased the intracellular ATP pool of E. coli and also inreased extracellular ATP, indicating disruptive action on the cytoplasmic membrane.
Journal ArticleDOI
Proteomic analysis of the mode of antibacterial action of silver nanoparticles
Chun-Nam Lok,Chi-Ming Ho,Rong Chen,Qing-Yu He,Wing-Yiu Yu,Hongzhe Sun,Paul K.H. Tam,Jen-Fu Chiu,Chi-Ming Che +8 more
TL;DR: Silver nanoparticles (nano-Ag) are potent and broad-spectrum antimicrobial agents and appear to be an efficient physicochemical system conferring antimicrobial silver activities.
References
More filters
Journal ArticleDOI
Molecular basis of bacterial outer membrane permeability.
Hiroshi Nikaido,Martti Vaara +1 more
TL;DR: It is becoming increasingly clear that the outer membrane is very important in the physiology of gram-negative bacteria in making them resistant to host defense factors such as lysozyme, P-lysin, and various leukocyte proteins.
Journal ArticleDOI
Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor
TL;DR: A family of peptides with broad-spectrum antimicrobial activity has been isolated from the skin of the African clawed frog Xenopus laevis and appears to represent a previously unrecognized class of vertebrate antimicrobial activities.
Journal ArticleDOI
Structure and function of lipopolysaccharide binding protein
R R Schumann,Steven R. Leong,Gail W. Flaggs,Patrick W. Gray,Samuel D. Wright,John C. Mathison,Peter S. Tobias,Richard J. Ulevitch +7 more
TL;DR: The identification of this pathway for LPS-induced monocyte stimulation may aid in the development of treatments for diseases in which Gram-negative sepsis or endotoxemia are involved.
Journal ArticleDOI
The release of enzymes from Escherichia coli by osmotic shock and during the formation of spheroplasts.
Harold C. Neu,Leon A. Heppel +1 more
TL;DR: A new method for releasing most of the inducible alkaline phosphatases and of the cyclic phosphodiesterase in high yield without greatly impairing the viability of the cells is developed.
Journal ArticleDOI
Defensins. Natural peptide antibiotics of human neutrophils.
Tomas Ganz,Michael E. Selsted,D Szklarek,Sylvia S. L. Harwig,Kathleen A. Daher,D F Bainton,Robert I. Lehrer +6 more
TL;DR: The defensin system may operate in conjunction with or independently from oxygen-dependent microbicidal processes to enable human neutrophils to inactivate and destroy potential pathogens.