Ambulatory diagnosis and treatment of nonmalignant pain in the united states, 2000-2010
Matthew Daubresse,Hsien Yen Chang,Yuping Yu,Shilpa Viswanathan,Nilay Shah,Randall S. Stafford,Stefan P. Kruszewski,G. Caleb Alexander +7 more
TLDR
Increased opioid prescribing has not been accompanied by similar increases in nonopioid analgesics or the proportion of ambulatory pain patients receiving pharmacologic treatment, suggesting clinical alternatives to prescription opioids may be underutilized as a means of treating ambulatory nonmalignant pain.Abstract:
Background:Escalating rates of prescription opioid use and abuse have occurred in the context of efforts to improve the treatment of nonmalignant pain.Objective:The aim of the study was to characterize the diagnosis and management of nonmalignant pain in ambulatory, office-based settings in the Unitread more
Citations
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Sex differences in morphine analgesia and the role of microglia in the periaqueductal gray of the rat
TL;DR: A mechanistic understanding is established of how the activation of vlPAG microglia sex-specifically influences morphine analgesia and a novel pharmacokinetic mechanism underlying the sexually dimorphic effects of morphine administration on microglial activity is investigated.
Older Adults’ Response to Adverse Opioid Related Events: A Secondary Analysis
TL;DR: The opioid ADE profile in older adults is similar to that of adults, but certain ADEs may be more common in Older adults, including dizziness, upset stomach, and fatigue.
Journal ArticleDOI
Opioid‐related adverse drug reactions in patients visiting the emergency division of a tertiary hospital
K. Ing Lorenzini,Laura Wainstein,Hervé Spechbach,François Sarasin,Majd Ramlawi,Jules Alexandre Desmeules,Valérie Piguet +6 more
TL;DR: In this article , the frequency and causes of opioid-related emergency division (ED) visits in an adult tertiary Swiss University Hospital over 9 weeks in 2018 were assessed, and the authors concluded that the ED visits could be related to opioid use in 10.2% of users.
Book ChapterDOI
Chronic Pain Management and Maxillofacial Surgery
TL;DR: Postoperative pain control is often challenging in this patient population, requiring identification of preoperative treatment regimens as well as making perioperative modifications to improve patient outcomes and patient satisfaction.
Journal ArticleDOI
Hospitalizations for opioid-related overdose and timing of concurrent opioid and benzodiazepine use: A nested case-control study
TL;DR: A nested case-control study was conducted using Truven MarketScan claims data (2009-2018) to evaluate the likelihood of opioid-related overdose across levels of duration, recency, and daily dose of concurrent use as discussed by the authors.
References
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Vital Signs: Overdoses of Prescription Opioid Pain Relievers - United States, 1999-2008
TL;DR: Wide variation among states in the nonmedical use of OPR and overdose rates cannot be explained by underlying demographic differences in state populations but is related to wide variations in OPR prescribing.
Journal ArticleDOI
Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects
TL;DR: Weak and strong opioids outperformed placebo for pain and function in all types of CNCP and were significantly superior to naproxen and nortriptyline, and only for pain relief.
Journal ArticleDOI
Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction.
Bridget Martell,Patrick G. O'Connor,Robert D. Kerns,William C. Becker,Knashawn H. Morales,Thomas R. Kosten,David A. Fiellin +6 more
TL;DR: This systematic review and meta-analysis addresses the following questions: Are opioid medications effective in treating chronic back pain?
Journal ArticleDOI
Treatment of chronic non-cancer pain
TL;DR: A general overview of empirical evidence for the most commonly used interventions in the management of chronic non-cancer pain, including pharmacological, interventional, physical, psychological, rehabilitative, and alternative modalities is provided.
Journal ArticleDOI
Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids.
TL;DR: Therapeutic opioid use has increased substantially, specifically of Schedule II drugs, and patients on long-term opioid use have been shown to increase the overall cost of healthcare, disability, rates of surgery, and late opioid use.
Related Papers (5)
CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain
Roger Chou,Gilbert J. Fanciullo,Perry G. Fine,Jeremy A Adler,Jane C. Ballantyne,Pamela Stitzlein Davies,Marilee I. Donovan,David A. Fishbain,Kathy M. Foley,Jeffrey Fudin,Aaron M. Gilson,Alexander Kelter,Alexander Mauskop,Patrick G. O'Connor,Steven D. Passik,Gavril W. Pasternak,Russell K. Portenoy,Ben A. Rich,Richard G. Roberts,Knox H. Todd,Christine Miaskowski +20 more