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Ambulatory diagnosis and treatment of nonmalignant pain in the united states, 2000-2010

TLDR
Increased opioid prescribing has not been accompanied by similar increases in nonopioid analgesics or the proportion of ambulatory pain patients receiving pharmacologic treatment, suggesting clinical alternatives to prescription opioids may be underutilized as a means of treating ambulatory nonmalignant pain.
Abstract
Background:Escalating rates of prescription opioid use and abuse have occurred in the context of efforts to improve the treatment of nonmalignant pain.Objective:The aim of the study was to characterize the diagnosis and management of nonmalignant pain in ambulatory, office-based settings in the Unit

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Nationally Representative Health Care Expenditures of Community-Based Older Adults with Pain in the United States Prescribed Opioids vs Those Not Prescribed Opioids

TL;DR: This study raises awareness of the economic impact associated with opioid use among US older adults with pain and suggests that future research should investigate these variables in greater depth, over longer time periods, and in additional populations.
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Association between fatal opioid overdose and state medical cannabis laws in US national survey data, 2000-2011

TL;DR: In this article , the authors used case-control design and individual-level data from national surveys to assess whether state medical cannabis laws were associated with reduced risk of fatal opioid overdose between 2000-2011.
Journal ArticleDOI

Association between fatal opioid overdose and state medical cannabis laws in US national survey data, 2000-2011

TL;DR: In this paper, the authors used a case-control design and individual-level data from national surveys to assess whether state medical cannabis laws were associated with reduced risk of fatal opioid overdose between 2000-2011.
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Independent Validation in a Large Privately Insured Population of the Risk Index for Serious Prescription Opioid–Induced Respiratory Depression or Overdose

TL;DR: The VHA-RIOSORD performed well in identifying members of a large private insurance company who were medical users of prescription opioids at elevated risk of overdose or life-threatening respiratory depression, those most likely to benefit from preventive interventions.
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The Impact of Chronic Opioid Use on Colonoscopy Outcomes

TL;DR: Patients on chronic opioids represent a high-risk population with longer procedural times and more discomfort, despite higher dosages of sedative agents, according to a retrospective review of endoscopic procedures performed on patients chronically on opioids.
References
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Vital Signs: Overdoses of Prescription Opioid Pain Relievers - United States, 1999-2008

TL;DR: Wide variation among states in the nonmedical use of OPR and overdose rates cannot be explained by underlying demographic differences in state populations but is related to wide variations in OPR prescribing.
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Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects

TL;DR: Weak and strong opioids outperformed placebo for pain and function in all types of CNCP and were significantly superior to naproxen and nortriptyline, and only for pain relief.
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Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction.

TL;DR: This systematic review and meta-analysis addresses the following questions: Are opioid medications effective in treating chronic back pain?
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Treatment of chronic non-cancer pain

TL;DR: A general overview of empirical evidence for the most commonly used interventions in the management of chronic non-cancer pain, including pharmacological, interventional, physical, psychological, rehabilitative, and alternative modalities is provided.
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Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids.

TL;DR: Therapeutic opioid use has increased substantially, specifically of Schedule II drugs, and patients on long-term opioid use have been shown to increase the overall cost of healthcare, disability, rates of surgery, and late opioid use.
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