Journal ArticleDOI
American thyroid association guidelines for detection of thyroid dysfunction
Paul W. Ladenson,Peter Singer,Kenneth B. Ain,N. Bagchi,S. Thomas Bigos,Elliot G. Levy,Steven A. Smith,Gilbert H. Daniels +7 more
TLDR
The American Thyroid Association recommends that adults be screened for thyroid dysfunction by measurement of the serum thyrotropin concentration, beginning at age 35 years and every 5 years thereafter.Abstract:
Objective To define the optimal approach to identify patients with thyroid dysfunction. Participants The 8-member Standards of Care Committee of the American Thyroid Association prepared a draft, which was reviewed by the association's 780 members, 50 of whom responded with suggested revisions. Evidence Relevant published studies were identified through MEDLINE and the association membership's personal resources. Consensus Process Consensus was reached at group meetings. The first draft was prepared by a single author (P.W.L.) after group discussion. Suggested revisions were incorporated after consideration by the committee. Conclusions The American Thyroid Association recommends that adults be screened for thyroid dysfunction by measurement of the serum thyrotropin concentration, beginning at age 35 years and every 5 years thereafter. The indication for screening is particularly compelling in women, but it can also be justified in men as a relatively cost-effective measure in the context of the periodic health examination. Individuals with symptoms and signs potentially attributable to thyroid dysfunction and those with risk factors for its development may require more frequent serum thyrotropin testing.read more
Citations
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Journal ArticleDOI
Serum TSH, T4, and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)
Joseph G. Hollowell,Norman W. Staehling,W. Dana Flanders,W. Harry Hannon,Elaine W. Gunter,Carole A. Spencer,Lewis E. Braverman +6 more
TL;DR: TSH and the prevalence of antithyroid antibodies are greater in females, increase with age, and are more in whites and Mexican Americans than in blacks, which needs more research to relate these findings to clinical status.
Journal ArticleDOI
Subclinical thyroid disease: scientific review and guidelines for diagnosis and management.
Martin I. Surks,Eduardo Ortiz,Gilbert H. Daniels,Clark T. Sawin,Nananda F. Col,Rhoda H. Cobin,J. A. Franklyn,Jerome M. Hershman,Kenneth D. Burman,Margo A. Denke,Margo A. Denke,Colum A. Gorman,Richard S. Cooper,Neil J. Weissman +13 more
TL;DR: The strength of the evidence that untreated subclinical thyroid disease is associated with clinical symptoms and adverse clinical outcomes was assessed and recommendations for clinical practice developed and insufficient evidence to support population-based screening was found.
Journal ArticleDOI
Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline.
Richard S. Legro,Silva A. Arslanian,David A. Ehrmann,Kathleen M. Hoeger,M. Hassan Murad,Renato Pasquali,Corrine K. Welt +6 more
TL;DR: Evaluation of women with PCOS should exclude alternate androgen-excess disorders and risk factors for endometrial cancer, mood disorders, obstructive sleep apnea, diabetes, and cardiovascular disease.
Journal ArticleDOI
Clinical Practice Guidelines for Hypothyroidism in Adults: Cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association
Jeffrey R. Garber,Jeffrey R. Garber,Rhoda H. Cobin,Hossein Gharib,James V. Hennessey,Irwin Klein,Jeffrey I. Mechanick,Rachel Pessah-Pollack,Peter Singer,Kenneth A. Woeber +9 more
TL;DR: Fifty-two evidence-based recommendations and subrecommendations were developed to aid in the care of patients with hypothyroidism and to share what the authors believe is current, rational, and optimal medical practice for the diagnosis and care of hyp Timothyroidism.
Journal ArticleDOI
The clinical significance of subclinical thyroid dysfunction.
TL;DR: The mechanisms underlying tissue alterations in SCTD and the effects of replacement therapy on progression and tissue parameters are examined, and the issue of the need to treat slight thyroid hormone deficiency or excess in relation to the patient's age is addressed.
References
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Journal ArticleDOI
The spectrum of thyroid disease in a community: the whickham survey
W.M.G. Tunbridge,D. C. Evered,Reginald Hall,D. Appleton,M Brewis,F. Clark,J G Evans,E. T. Young,T. Bird,P. A. Smith +9 more
TL;DR: TSH levels above 6 mu/1 were shown to reflect a significant lowering of circulating thyroxine levels and showed a strong association with thyroid antibodies in both sexes, independent of age.
Journal ArticleDOI
The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey
M. P. J. Vanderpump,W. M. G. Tunbrldge,J.M. French,D. Appleton,David W. Bates,F. Clark,J. Grimley Evans,D. M. Hasan,Helen Rodgers,F. Tunbridge,E. T. Young +10 more
TL;DR: The aim of the twenty‐year follow-up survey was to determine the Incidence and natural history of thyroid disease in this cohort.
Journal ArticleDOI
Low Serum Thyrotropin Concentrations as a Risk Factor for Atrial Fibrillation in Older Persons
Clark T. Sawin,Andrew I. Geller,Philip A. Wolf,Albert J. Belanger,Errol Baker,Pamela Bacharach,Peter W.F. Wilson,Emelia J. Benjamin,Ralph B. D'Agostino +8 more
TL;DR: Among people 60 years of age or older, a low serum thyrotropin concentration is associated with a threefold higher risk that atrial fibrillation will develop in the subsequent decade.
Book
Werner & Ingbar's the thyroid : a fundamental and clinical text
TL;DR: This edition of The Thyroid has added the surgical management of thyroid disorders which is clearly an asset for the endocrine surgeon and is clearly essential for endocrinologists and thyroid surgeons.
Book
Guide to Clinical Preventive Services: Report of the U S Preventive Services Task Force
TL;DR: This text, written by the US Preventive Services Task Force, provides a guide to public health preventive medicine.