Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline.
Richard S. Legro,Silva A. Arslanian,David A. Ehrmann,Kathleen M. Hoeger,M. Hassan Murad,Renato Pasquali,Corrine K. Welt +6 more
TLDR
Evaluation of women with PCOS should exclude alternate androgen-excess disorders and risk factors for endometrial cancer, mood disorders, obstructive sleep apnea, diabetes, and cardiovascular disease.Abstract:
Objective: The aim was to formulate practice guidelines for the diagnosis and treatment of polycystic ovary syndrome (PCOS). Participants: An Endocrine Society-appointed Task Force of experts, a methodologist, and a medical writer developed the guideline. Evidence: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. Consensus Process: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of The Endocrine Society and the European Society of Endocrinology reviewed and commented on preliminary drafts of these guidelines. Two systematic reviews were conducted to summarize supporting evidence. Conclusions: We suggest using the Rotterdam criteria for diagnosing PCOS (presence of two of the following criteria: androgen excess, ovulatory dysfunction, or polycystic ovaries). Establishing a diagno...read more
Citations
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Journal ArticleDOI
Polycystic ovary syndrome.
Ricardo Azziz,Enrico Carmina,Zi-Jiang Chen,Andrea Dunaif,Joop S.E. Laven,Richard S. Legro,Daria Lizneva,Daria Lizneva,Barbara Natterson-Horowtiz,Helena J. Teede,Bulent O. Yildiz +10 more
TL;DR: PCOS can impact women’s reproductive health, leading to anovulatory infertility and higher rate of early pregnancy loss, and the risks of diabetes, cardiovascular disease, hypertension, metabolic syndrome, and endometrial cancer among PCOS patients are significantly increased.
Journal ArticleDOI
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome
Helena J. Teede,Helena J. Teede,Marie Misso,Marie Misso,Michael F. Costello,Anuja Dokras,Joop S.E. Laven,Lisa J. Moran,Lisa J. Moran,Terhi Piltonen,Robert J. Norman,Robert J. Norman,Marianne Andersen,Ricardo Azziz,Adam H. Balen,Estifanos Baye,Jacqueline Boyle,Leah Brennan,Frank J.M. Broekmans,Preeti Dabadghao,Luigi Devoto,Didier Dewailly,Linda Downes,Bart C.J.M. Fauser,Stephen Franks,Rhonda Garad,Melanie Gibson-Helm,Cheryce L. Harrison,Roger Hart,Rachel Hawkes,Angelica Lindén Hirschberg,Kathleen M. Hoeger,Femke P Hohmann,Samantha K. Hutchison,Anju E. Joham,Louise Johnson,Cailin Jordan,Jayashri Kulkarni,Richard S. Legro,Rong Li,Marla E. Lujan,Jaideep Malhotra,Darren Mansfield,Kate Marsh,Veryan McAllister,Edgar Mocanu,Ben W.J. Mol,Ernest Hung Yu Ng,Sharon E. Oberfield,Sasha Ottey,Alexia S Peña,Jie Qiao,Leanne M. Redman,Raymond J. Rodgers,Luk Rombauts,Daniela Romualdi,Duru Shah,Jane Speight,Poli Mara Spritzer,Elisabet Stener-Victorin,Nigel K. Stepto,Juha S. Tapanainen,Eliza C. Tassone,Shakila Thangaratinam,Mala Thondan,Chii Ruey Tzeng,Zephne M van der Spuy,Eszter Vanky,Maria G. Vogiatzi,Angela Wan,Chandrika N Wijeyaratne,Selma F. Witchel,Jane Woolcock,Bulent O. Yildiz +73 more
TL;DR: The international guideline for the assessment and management of PCOS provides clinicians with clear advice on best practice based on the best available evidence, expert multidisciplinary input and consumer preferences to promote consistent, evidence-based care and improve the experience and health outcomes of women with PCOS.
Diagnostic criteria for polycystic ovary syndrome
TL;DR: It is suggested that ultrasound, laparoscopic, hormonal and endometrial parameters should be employed as diagnostic criteria for ovarian polycystosis.
Journal ArticleDOI
American association of clinical endocrinologists and american college of endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity.
W. Timothy Garvey,Jeffrey I. Mechanick,Elise M. Brett,Alan J. Garber,Daniel L. Hurley,Ania M. Jastreboff,Karl Nadolsky,Rachel Pessah-Pollack,Raymond A Plodkowski +8 more
TL;DR: The final recommendations recognize that obesity is a complex, adiposity-based chronic disease, where management targets both weight-related complications and adiposity to improve overall health and quality of life.
Journal ArticleDOI
Guidelines of care for the management of acne vulgaris
Andrea L. Zaenglein,Arun L. Pathy,Bethanee J. Schlosser,Ali Alikhan,Hilary Baldwin,Diane Berson,Diane Berson,Whitney P. Bowe,Emmy M. Graber,Julie C Harper,Sewon Kang,Jonette E. Keri,James J. Leyden,Rachel V. Reynolds,Nanette Silverberg,Linda Stein Gold,Megha M. Tollefson,Jonathan S. Weiss,Nancy C. Dolan,Andrew A. Sagan,Mackenzie Stern,Kevin Boyer,Reva Bhushan +22 more
TL;DR: Issues from grading of acne to the topical and systemic management of the disease are reviewed and suggestions on use are provided based on available evidence.
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William C. Knowler,Elizabeth Barrett-Connor,Sarah E. Fowler,Richard F. Hamman,John M. Lachin,Elizabeth A. Walker,David M. Nathan +6 more
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Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
TL;DR: Since the 1990 NIH-sponsored conference on polycystic ovary syndrome, it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria.
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Ricardo Azziz,Keslie S. Woods,Rosario Reyna,Timothy J. Key,Eric S. Knochenhauer,Bulent O. Yildiz +5 more
TL;DR: Data from a large representative unselected population support the concept that PCOS is the most common endocrine abnormality of reproductive-aged women in the United States.
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Bart C.J.M. Fauser,Basil C. Tarlatzis,Robert W. Rebar,Richard S. Legro,Adam H. Balen,Roger A. Lobo,Enrico Carmina,Jeffrey P. Chang,Bulent O. Yildiz,Joop S.E. Laven,Jacky Boivin,Felice Petraglia,C. N. Wijeyeratne,Robert J. Norman,Andrea Dunaif,Stephen Franks,Robert A. Wild,Daniel A. Dumesic,Kurt T. Barnhart +18 more