An expanded cohort study of cancer among benzene-exposed workers in China
Songnian Yin,Richard B. Hayes,Martha S. Linet,Gui Lan Li,Mustafa Dosemeci,Lois B. Travis,Zhi Nan Zhang,De Gao Li,Wong Ho Chow,Sholom Wacholder,William J. Blot,Y. Z. Wang,Z. L. Jiang,T. R. Dai,Wan You Zhang,X. Y. Chao,P. Z. Ye,Q. R. Kou,X. C. Chang,X. F. Lin,J. F. Meng,Cheng Yu Ding,J. S. Zho +22 more
TLDR
An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China, and a small increase was observed in total cancer mortality.Abstract:
An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed Workers (relative risk [RR] = 1-2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia. 19 refs., 5 tabs.read more
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References
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Benzene and leukemia. An epidemiologic risk assessment.
Robert A. Rinsky,Alexander B. Smith,Richard W. Hornung,Thomas G. Filloon,Ronald J. Young,Andrea H. Okun,Philip J. Landrigan +6 more
TL;DR: Using actual air sampling data to estimate individual exposures represents a marked improvement over these previous attempts and emphasizes the importance of conducting industrial hygiene surveys and maintaining historical exposure records.
Journal ArticleDOI
Leukemia in benzene workers.
TL;DR: Reconstruction of past exposures to benzene at the two locations indicates that in some areas of the plant airborne benzene concentrations rose occasionally to several hundred parts per million (ppm), but that for the most part, employee eight-hour time-weighted averages (TWA) fell within the limits considered permissible at the time of exposure.
Journal ArticleDOI
Leukæmia in benzene workers
TL;DR: Workers occupationally exposed to benzene in 1940-49 were followed for vital status up to 1975 and a significant change in status was found in comparison with two control populations.
Journal ArticleDOI
Major Sources of Benzene Exposure
TL;DR: Data from EPA's TEAM Study allow us to identify the major sources of exposure to benzene for much of the U.S. population, and these sources turn out to be quite different from what had previously been considered the important sources.
Journal ArticleDOI
A cohort study of cancer among benzene-exposed workers in China: overall results.
Songnian Yin,Richard B. Hayes,Martha S. Linet,Gui Lan Li,Mustafa Dosemeci,Lois B. Travis,Chin Yang Li,Zhi Nan Zhang,De Gao Li,Wong Ho Chow,Sholom Wacholder,Yao Zu Wang,Z. L. Jiang,T. R. Dai,Wan You Zhang,X. ‐J Chao,P. Z. Ye,Q. R. Kou,Xi Chun Zhang,X. F. Lin,J. F. Meng,Cheng Yu Ding,J. S. Zho,William J. Blot +23 more
TL;DR: Employment in benzene-associated occupations in China is associated with a wide spectrum of myelogenous and lymphocytic malignant diseases and related disorders, and Investigations continue to assess the nature of these associations.
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