Journal ArticleDOI
Analysis of factors contributing to treatment failures in Stages IB and IIA carcinoma of the cervix
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TLDR
Patients who had bulky primary tumors and/or grossly positive nodes at laparatomy may require systemic therapy in view of the high incidence of distant failures.About:
This article is published in American Journal of Obstetrics and Gynecology.The article was published on 1980-11-01. It has received 186 citations till now.read more
Citations
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Journal ArticleDOI
A Randomized Trial of Pelvic Radiation Therapy versus No Further Therapy in Selected Patients with Stage IB Carcinoma of the Cervix after Radical Hysterectomy and Pelvic Lymphadenectomy: A Gynecologic Oncology Group Study
Alexander Sedlis,Brian N. Bundy,Marvin Rotman,Samuel S. Lentz,Laila I. Muderspach,Richard J. Zaino +5 more
TL;DR: Adjuvant pelvic radiotherapy following radical surgery reduces the number of recurrences in women with Stage IB cervical cancer at the cost of 6% grade 3/4 adverse events versus 2.1% in the NFT group.
Journal ArticleDOI
A phase III randomized trial of postoperative pelvic irradiation in Stage IB cervical carcinoma with poor prognostic features: follow-up of a gynecologic oncology group study.
Marvin Rotman,Alexander Sedlis,Marion Piedmonte,Brian N. Bundy,Samuel S. Lentz,Laila I. Muderspach,Richard J. Zaino +6 more
TL;DR: Pelvic radiotherapy after radical surgery significantly reduces the risk of recurrence and prolongs progression-free survival in women with Stage IB cervical cancer and appears to be particularly beneficial for patients with adenocarcinoma or adenosquamous histologies.
Journal ArticleDOI
Carcinoma of the cervix treated with radiation therapy. I. A multi-variate analysis of prognostic variables in the Gynecologic Oncology Group.
Frederick B. Stehman,Brian N. Bundy,Philip J. DiSaia,Henry M. Keys,James E. Larson,Wesley C. Fowler +5 more
TL;DR: Multi‐variate analysis showed patient age, performance status (PS), PA lymph node status, tumor size, and pelvic node status to be significantly associated with PFI.
Journal ArticleDOI
Quality of Life and Sexual Functioning in Cervical Cancer Survivors
Michael Frumovitz,Charlotte C. Sun,Leslie R. Schover,Mark F. Munsell,Anuja Jhingran,J. Taylor Wharton,Patricia J. Eifel,Therese B. Bevers,Charles F Levenback,David M. Gershenson,Diane C. Bodurka +10 more
TL;DR: In this article, the authors compared the quality of life and sexual functioning in cervical cancer survivors treated with either radical hysterectomy and lymph node dissection or radiotherapy.
Journal ArticleDOI
Effect of tumor size on the prognosis of carcinoma of the uterine cervix treated with irradiation alone
Carlos A. Perez,Perry W. Grigsby,Shriram M. Nene,H. Marvin Camel,Andrew E. Galakatos,Ming-Shian Kao,Mary Ann Lockett +6 more
TL;DR: It is concluded that clinical stage and size of tumor are critical factors in the prognosis, therapy selection, and evaluation of results in carcinoma of the uterine cervix.
References
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Journal Article
Prognostic significance of cervical lesion size and pelvic node metastases in cervical carcinoma.
TL;DR: Excellent 5-year survival rates for women with Stage IB cervical carcinoma were associated with cervical lesions measuring less than 3 cm and resected pelvic lymph nodes which did not contain metastatic cancer.
Journal Article
Preirradiation celiotomy and extended field irradiation for invasive carcinoma of the cervix.
TL;DR: Recurrent carcinoma usually appeared as distant metastases outside the treatment area which suggests that patients with bulky primary lesions and positive nodes actually already have systemic disease as treatment is started.
Journal ArticleDOI
The significance of vascular invasion and lymphocytic infiltration in invasive cervical cancer.
TL;DR: Surgical specimens from 100 patients with stage I B cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy were reviewed with respect to vascular invasion and lymphoplasmacytic infiltration.
Journal ArticleDOI
Radical Hysterectomy and Pelvic Lymphadenectomy: A Review of 473 Cases Including 244 for Primary Invasive Carcinoma of the Cervix
Winifred Liu,Joe Vincent Meigs +1 more
Journal ArticleDOI
The effect of radiation therapy on pelvic lymph node involvement in Stage I carcinoma of the cervix
L.D. Lagasse,L.D. Lagasse,M.L. Smith,M.L. Smith,J.G. Moore,J.G. Moore,D.G. Morton,D.G. Morton,M. Jacobs,M. Jacobs,G.H. Johnson,G.H. Johnson,W.G. Watring,W.G. Watring +13 more
TL;DR: The results suggest that radiation can eradicate metastatic carcinoma from lymph nodes in a portion of the cases and information regarding the presence or absence of nodal metastases is useful in planning therapy and predicting outcome.