Journal ArticleDOI
Analysis of gangliosides using fast atom bombardment mass spectrometry.
Heinz Egge,Jasna Peter-Katalinic,Gerd Reuter,Roland Schauer,Riccardo Ghidoni,Sandro Sonnino,Guido Tettamanti +6 more
TLDR
The data show, that the combination of soft ionization mass spectrometry with classical EI-MS gives valuable information on the structure and homogeneity of gangliosides.About:
This article is published in Chemistry and Physics of Lipids.The article was published on 1985-05-01. It has received 67 citations till now. The article focuses on the topics: Fast atom bombardment & Mass spectrometry.read more
Citations
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Book ChapterDOI
F.A.B.-Mass Spectrometry of Carbohydrates
TL;DR: On its own, FAB-MS cannot solve the complete structure of a carbohydrate and it should always be incorporated into experimental programs that include the well established methods of methylation analysis, enzymic digestion, chemical degradation, and nuclear magnetic resonance (NMR) spectroscopy.
Journal ArticleDOI
Structure elucidation of glycosphingolipids and gangliosides using high-performance tandem mass spectrometry.
TL;DR: Glycosphingolipids and gangliosides have been investigated by using fast atom bombardment high-performance tandem mass spectrometry (FABMS/MS) and the exclusion of most of the interfering signals from the matrix allows the identification of pertinent fragments at low mass.
Journal ArticleDOI
Fast atom bombardment mass spectrometry for structural elucidation of glycoconjugates
Heinz Egge,Jasna Peter-Katalinic +1 more
Book ChapterDOI
Biochemistry and Role of Sialic Acids
TL;DR: Research on the structures, metabolism, and molecular biology, as well as on the biological and clinical importance of sialic acids as components of these glycoconjugates, has therefore intensified during the past several years.
Journal ArticleDOI
Ganglioside molecular species containing C18- and C20-sphingosine in mammalian nervous tissues and neuronal cell cultures.
Sandro Sonnino,Vanna Chigorno +1 more
TL;DR: The hypothesis that the varying ratio between C18- and C20-gangliosides during CNS development and aging can be instrumental in modulating membrane domain organisation and cell properties is introduced.
References
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Journal ArticleDOI
A Rapid Permethylation of Glycolipid, and Polysaccharide Catalyzed by Methylsulfinyl Carbanion in Dimethyl Sulfoxide
TL;DR: It was undertaken to demonstrate the presence of various kinds of acyl residue in this solvent by ` hydroxylaminolysis' of the urinary glyco protein.
Journal ArticleDOI
A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II.
J L Magnani,B. Nilsson,M Brockhaus,David Zopf,Zenon Steplewski,Hilary Koprowski,Victor Ginsburg +6 more
TL;DR: Two monoclonal antibodies produced by hybridomas obtained from a mouse immunized with a colorectal carcinoma cell line bind specifically to human gastrointestinal cancer cells.
Journal ArticleDOI
A new procedure for the extraction, purification and fractionation of brain gangliosides.
TL;DR: This procedure, compared with the conventional chloroform-methanol procedure, was proved to achieve a more complete extraction of gangliosides with no concurrent solubilization of glycoproteins and to guarantee the absence of any significant degradation.
Related Papers (5)
Fast atom bombardment mass spectrometry for structural elucidation of glycoconjugates
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A procedure for the quantitative isolation of brain gangliosides.
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