scispace - formally typeset
Patent

Anti-angiogenic compositions and methods of use

Reads0
Chats0
TLDR
In this article, an anti-angiogenic factor and a polymeric carrier were used for embolization of blood vessels and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.
Abstract
The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.

read more

Citations
More filters
Patent

Coated implantable medical device

TL;DR: A coated implantable medical device as discussed by the authors includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract.
Patent

Therapeutic inhibitor of vascular smooth muscle cells

TL;DR: In this paper, the authors present methods for the direct and/or targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent.
Patent

Medical devices and applications of polyhydroxyalkanoate polymers

TL;DR: In this paper, the degradation times of polyhydroxyalkanoates are controlled under physiological conditions, and the degradation rates are controlled with less than one year under certain physiological conditions.
Patent

Silver implantable medical device

TL;DR: In this paper, a coronary stent implantable medical device is defined as a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract.
Patent

Drug coating with topcoat

TL;DR: In this paper, a method for a coating an implantable device or prosthesis is described, which includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein.
References
More filters
Patent

Method of preparing adhesive dressings containing a pharmaceutically active ingredient

TL;DR: A dressing comprising a flexible backing member and a pressure sensitive adhesive layer is described in this article, where a dispersion of the active ingredient in a medium compatible with the adhesive layer was laminated to the skin contacting surface.
Journal ArticleDOI

Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver.

TL;DR: The prominent markers of endoplasmic reticulum from which autophagosomes originate are well preserved in autophagic vacuole membranes, and retention of these markers is highly dependent on the formation and subsequent maturation process of autophotic vacuoles.
Journal Article

Overview of Taxol safety.

TL;DR: The safety profile of Taxol administered intravenously as a single agent has been established based on the experience of 655 patients and myelosuppression was the dose-limiting toxicity in all studies conducted in patients with solid tumors.
Journal Article

Inhibition of Tumor-induced Angiogenesis by Sulfated Chitin Derivatives

TL;DR: Results suggest that inhibition of lung tumor metastasis by SCM-chitin III may in part be due to the inhibition of tumor-associated angiogenesis.
Patent

Method, apparatus, and substance for treating tissue having neoplastic cells

TL;DR: In this article, a method for releasing at a temperature above normal tissue temperature an anti-cancer drug and applying heat in combination to tissue having neoplastic cells such as a malignant brain tumor is described.