Patent
Anti-angiogenic compositions and methods of use
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TLDR
In this article, an anti-angiogenic factor and a polymeric carrier were used for embolization of blood vessels and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Abstract:
The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.read more
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References
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Interaction of taxol and other anticancer drugs with hydroxypropyl-β-cyclodextrin
Tibor Cserháti,J. Holló +1 more
TL;DR: In this paper, the interaction between 23 anticancer drugs and hydroxypropyl-β-cyclodextrin (HPβCD) was studied by reversed phase charge-transfer thin-layer chromatography and the relative strength of interaction was calculated.
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Evaluation of poly(isobutylcyanoacrylate) nanoparticles for mucoadhesive ocular drug delivery. I: Effect of formulation variables on physicochemical characteristics of nanoparticles
TL;DR: A factorial design was applied to evaluate the effect of formulation variables on physicochemical properties of poly(isobutylcyanoacrylate) nanoparticles and a wide range of molecular weight distribution was observed.
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Sustained release of isoniazid in vivo from a single implant of a biodegradable polymer
TL;DR: Attempts were made to prolong the bioavailability of antimycobacterial drugs after a single administration of polylactic-co-glycolic acid (PLGA) co-polymer containing isoniazid, which ensured its sustained release up to 6 weeks.
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Drug release from a new family of biodegradable polyanhydrides
TL;DR: In this paper, the effect of copolymer properties (e.g., hydrophobicity, crystallinity, drug properties) and drug loading on drug release was investigated.
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