Patent
Anti-angiogenic compositions and methods of use
Reads0
Chats0
TLDR
In this article, an anti-angiogenic factor and a polymeric carrier were used for embolization of blood vessels and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.Abstract:
The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.read more
Citations
More filters
Patent
Coated implantable medical device
TL;DR: A coated implantable medical device as discussed by the authors includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract.
Patent
Therapeutic inhibitor of vascular smooth muscle cells
TL;DR: In this paper, the authors present methods for the direct and/or targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent.
Patent
Medical devices and applications of polyhydroxyalkanoate polymers
TL;DR: In this paper, the degradation times of polyhydroxyalkanoates are controlled under physiological conditions, and the degradation rates are controlled with less than one year under certain physiological conditions.
Patent
Silver implantable medical device
Anthony O. Ragheb,Brian L. Bates,Neal E. Fearnot,Thomas A. Osborne,Thomas G. Kozma,Joseph W. Roberts,William D. Voorhees +6 more
TL;DR: In this paper, a coronary stent implantable medical device is defined as a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract.
Patent
Drug coating with topcoat
Ni Ding,Michael N. Helmus +1 more
TL;DR: In this paper, a method for a coating an implantable device or prosthesis is described, which includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein.
References
More filters
Journal Article
Ultrastructural aspects of colchicine ultrasensitivity in CLL lymphocytes.
Allen Td,Scarffe Jh,Crowther D +2 more
TL;DR: A time course series of fixations during the 20-h exposure of chronic lymphoid leukaemia (CLL) lymphocytes to 10(-7) colchicine revealed an entire spectrum of ultrastructural alterations well in advance of any sign of cell death, previously only ascertained by nuclear pycnosis in the light microscope.
Journal ArticleDOI
Taxol inhibits N-formyl-methionyl-leucyl-phenylalanine (FMLP)-induced human neutrophil polarization and H2O2 production while decreasing [3H]FMLP binding
TL;DR: The decreased binding ofFMLP to its receptor may be responsible for the inhibition by taxol of FMLP-induced polarization and H2O2 generation.
Patent
Pharmaceutical compositions containing vanadium
TL;DR: In this paper, aqueous solutions of vanadyl gluconate and magnesium thiosulphate are used for anti-arteriosclerotic and anti-tumour activity.
Journal ArticleDOI
A Drug System (pdh) for Interventional Radiology Synthesis, Properties, and Efficacy
Ralph Weissleder,Alexei A. Bogdanov,Herbert Frank,Naseem Nossiff,Anna Bogdanova,B. Schaffer,Thomas J. Brady,Jack Wittenberg +7 more
TL;DR: PDH and its derivatives are relatively nontoxic, biodegradable materials for use in radiologic interventions and as a vehicle for sustained drug release.