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Antimicrobial Activity Of Some Indian Medicinal Plants

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TLDR
Water extracts of Acacia nilotica, Justicia zelanica, Lantana camara and Saraca asoca exhibited good activity against all the bacteria tested and the MIC was recorded in range of 9.375-37.5 microg/ml.
Abstract
The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of Acacia nilotica, Justicia zelanica, Lantana camara and Saraca asoca exhibited good activity against all the bacteria tested and the MIC was recorded in range of 9.375-37.5 microg/ml and 75.0-300.0 microg/ml against the bacterial and fungal pathogens, respectively. The other extracts of Phyllanthus urinaria, Thevetia nerifolia, Jatropha gossypifolia Saraca asoca, Tamarindus indica, Aegle marmelos, Acacia nilotica, Chlorophytum borivilianum, Mangifera indica, Woodfordia fruticosa and Phyllanthus emblica showed antimicrobial activity in a range of 75-1200 microg/ml.

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Antimicrobial effects of Aqueous Butanolic extract of Saraca Indica (Linn).

Rajesh Singh, +1 more
TL;DR: Results clearly indicate that Saraca indica has the antimicrobial properties, which are found in case of usual antibiotics.

Evaluatioof the aalgesic ad atipyretic actios of the saraca asoca leaves iexperimetal aimal models.

TL;DR: The results showed that the extract significantly inhibited the tail flick response of rats and increased the reaction time after dose administration, which was found to be independent of the route of administration of the drug.
Journal ArticleDOI

A Review on Herbal Extracts in Dentistry: Current Scenario and Future Trends

TL;DR: The research assessing the antimicrobial efficacy of a combination of these plant extracts against dental caries and periodontal pathogens is the need of the hour, and such research will aid in the development of a novel, innovative method that can simultaneously inhibit two of the most common dental diseases of mankind, besides slowing theDevelopment of drug resistance.
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Antibacterial Actions and Potential Phototoxic Effects of Volatile oils of Foeniculum sp. (fennel), Salvia sp. (sage), Vitis sp. (grape), Lavandula sp. (lavender)

TL;DR: In vitro, significant phototoxicity was demonstrated by volatile oil of Foeniculum sp.
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Comparative evaluation of the antioxidant potential of selected Indian medicinal plants

TL;DR: The present study clearly emphasizing the antioxidant potential of these plants and their importance in rasayana and the effect of the plant extracts on lipid peroxidation.
References
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Journal ArticleDOI

Antibacterial and antifungal activity of traditional medicinal plants used against venereal diseases in South Africa

TL;DR: The aqueous extracts of Gunnera perpensa and Harpephyllum caffrum were most active against all the tested bacteria and in antifungal screening, good activity was shown by the ethanolic extracts of Bersama lucens and HarPEphyllums caffrums.
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Multicenter evaluation of a broth macrodilution antifungal susceptibility test for yeasts.

TL;DR: Overall, the studies indicated that readings from the lower inoculum obtained on the second day of reading result in the greatest interlaboratory agreement, which will be used by the National Committee for Clinical Laboratory Standards to develop a standardized method for in vitro antifungal susceptibility testing for yeasts.
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Fungal infection in surgical patients

TL;DR: Invasive fungal infections have become a major source of morbidity and mortality in the modern surgical intensive care unit (SICU), and early systemic treatment is warranted as mentioned in this paper, however, for the most critically ill patient amphotericin B remains the treatment of choice.
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Inactivation of the methicillin resistance gene mecA in vancomycin-resistant Staphylococcus aureus.

TL;DR: Sequencing of the mecA gene resident in mutant VM50 indicated the presence of a 19-bp duplication between nucleotide residues 280-298, leading to the generation of a stop codon TAA starting at nucleotide position 286.
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A novel antifungal pyrrole derivative from Datura metel leaves

TL;DR: Two proteins having molecular weights of 42 and 58 kD of Aspergillus fumigatus are potential targets for compound 1, which was endowed with antifungal activity and its MIC was found to be 87.5 microg/ml.
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