Antimicrobial effects of Indian medicinal plants against acne-inducing bacteria
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The data indicated that Coscinium fenestratum had a strong inhibitory effect on Propionibacterium acnes and Staphylococcus epidermidis.Abstract:
Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. The present study was conducted to evaluate antimicrobial activities of Indian medicinal plants against these etiologic agents of acne vulgaris. Ethanolic extracts of Hemidesmus indicus (roots), Eclipta alba (fruits), Coscinium fenestratum (stems), Curcubito pepo (seeds), Tephrosia purpurea (roots), Mentha piperita (leaves), Pongamia pinnata (seeds), Symplocos racemosa (barks), Euphorbia hirta (roots), Tinospora cordyfolia (roots), Thespesia populnea (roots), and Jasminum officinale (flowers) were tested for antimicrobial activities by disc diffusion and broth dilution methods. The results from the disc diffusion method showed that 07 medicinal plants could inhibit the growth of Propionibacterium acnes. Among those Hemidesmus indicus, Coscinium fenestratum, Tephrosia purpurea, Euphorbia hirta, Symplocos racemosa, Curcubito pepo and Eclipta alba had strong inhibitory effects. Based on a broth dilution method, the Coscinium fenestratum extract had the greatest antimicrobial effect. The MIC values were the same (0.049 mg/ml) for both bacterial species and the MBC values were 0.049 and 0.165 mg/ml against Propionibacterium acnes and Staphylococcus epidermidis, respectively. In bioautography assay, the Coscinium fenestratum extract produced strong inhibition zones against Propionibacterium acnes. Phytochemical screening of Coscinium fenestratum revealed the presence of alkaloid which could be responsible for activity. Taken together, our data indicated that Coscinium fenestratum had a strong inhibitory effect on Propionibacterium acnes and Staphylococcus epidermidis.read more
Citations
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References
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Antimicrobial screening of selected medicinal plants from India
TL;DR: From the Indian traditional medicines 78 plants were selected on the basis of their use in the treatment of infectious diseases and only 13% of the plant extracts were active against at least one fungus in a concentration of 50 mg/ml.
Journal ArticleDOI
Evaluation of antimicrobial activities of Satureja hortensis L.
Fikrettin Şahin,Isa Karaman,Medine Gulluce,H. Ogutcu,Meryem Sengul,Ahmet Adiguzel,Suzan Ozturk,Recep Kotan +7 more
TL;DR: The results showed that hexane extract of Satureja hortensis had no antifungal, but antibacterial activity against four strains of three Bacillus species whereas methanol extract had both anticandidal and antibacterial effects.
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Therapy for Acne Vulgaris
TL;DR: This review summarizes current concepts of the rational treatment of acne vulgaris and explains the pathogenesis of acne is multifactorial, and therapy can be directed at many of these factors.
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Toxicity of Australian essential oil Backhousia citriodora (Lemon myrtle). Part 1. Antimicrobial activity and in vitro cytotoxicity.
A.J. Hayes,B. Markovic +1 more
TL;DR: In vitro cytotoxicity testing indicated that both lemon myrtle oil and citral had a very toxic effect against human cell lines and could potentially be used in the formulation of topical antimicrobial products.
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Evaluation of antioxidant properties of root bark of Hemidesmus indicus R. Br. (Anantmul)
TL;DR: The methanolic extract of H. indicus root bark was found to have different levels of antioxidant properties in the models tested, suggesting that the free radical scavenging property may be one of the mechanisms by which this drug is effective in several free radical mediated disease conditions.