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Journal ArticleDOI

Applying the Grades of Recommendation for Antithrombotic and Thrombolytic Therapy : The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

TLDR
In this article, grades of recommendation for antithrombotic and thrombolytic therapy are given by considering the trade-off between the benefits of a treatment and the risks, burdens, and costs.
About
This article is published in Chest.The article was published on 2004-09-01. It has received 119 citations till now. The article focuses on the topics: Observational study.

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Surviving sepsis campaign: international guidelines for the management of severe sepsis and septic shock: 2008

TL;DR: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, the GRADE system was used to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations.
Journal ArticleDOI

American Society of Clinical Oncology Guideline: Recommendations for Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer

TL;DR: Recommendations were developed on the prevention of VTE in hospitalized, ambulatory, and surgical cancer patients as well as patients with established VTE, and for use of anticoagulants in cancer patients without VTE to improve survival.
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Journal Article

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events(CAPRIE).

Denis Clement
- 01 Jan 1996 - 
TL;DR: Long-term administration of clopidogrel to patients with atherosclerotic vascular disease is more effective than aspirin in reducing the combined risk of ischaemic stroke, myocardial infarction, or vascular death.
Journal ArticleDOI

Prevention of venous thromboembolism

TL;DR: The risk factors for VTE among hospitalized patients are outlined, the efficacy and safety of alternative prophylaxis regimens are reviewed, and recommendations regarding the most suitable prophymic regimens based on the estimated risk are provided.
Journal ArticleDOI

Antithrombotic Therapy To Prevent Stroke in Patients with Atrial Fibrillation: A Meta-Analysis

TL;DR: A meta-analysis of all currently available trials to further characterize the comparative efficacy and safety of antithrombotic therapy for the prevention of stroke in patients with atrial fibrillation is presented.
Journal ArticleDOI

Heparin and Low-Molecular-Weight Heparin Mechanisms of Action, Pharmacokinetics, Dosing, Monitoring, Efficacy, and Safety

TL;DR: This chapter will review the mechanisms of action of heparin and LMWHs, their pharmacokinetics, anticoagulant effects, side effects, and laboratory monitoring, and the results of clinical trials will be discussed.
Journal ArticleDOI

Rules of Evidence and Clinical Recommendations on the Use of Antithrombotic Agents

TL;DR: The nonexperimental evidence that forms the recalled experiences of seasoned clinicians will tend to overestimate efficacy for the following reasons:.
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