Journal ArticleDOI
Assessment of local control after laser-induced thermotherapy of liver metastases from colorectal cancer: contribution of FDG-PET in patients with clinical suspicion of progressive disease.
Timm Denecke,Ingo G. Steffen,Bert Hildebrandt,R. Rühl,Florian Streitparth,Lukas Lehmkuhl,Jan M. Langrehr,Jens Ricke,Holger Amthauer,E. Lopez Hänninen +9 more
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TLDR
FDG-PET is a promising tool for the assessment of local control and whole-body restaging in patients with clinical suspicion of tumor progression after locally ablative treatment of colorectal liver metastases with LITT.Abstract:
Background: Management of patients after locally ablative treatment of liver metastases requires exact information about local control and systemic disease status. To fulfill these requirements, whole-body imaging using positron emission tomography with 18F-fluorodeoxyglucose (FDG-PET) is a promising alternative to morphologic imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI).Purpose: To evaluate FDG-PET for the assessment of local control and systemic disease in patients with clinical suspicion of tumor progression after laser-induced thermotherapy (LITT) of colorectal liver metastases.Material and Methods: In 21 patients with suspicion of progressive disease after LITT, whole-body FDG-PET was performed. The presence of viable tumor within treated lesions, new liver metastases, and extrahepatic disease was evaluated visually and semiquantitatively (maximal standard uptake value [SUVmax], tumor-to-normal ratio [T/N]). The standard of reference was histopathology (n =...read more
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Monitoring and predicting response to therapy with 18F-FDG PET in colorectal cancer: a systematic review.
Lioe-Fee de Geus-Oei,Dennis Vriens,Hanneke W. M. van Laarhoven,Winette T. A. van der Graaf,Wim J.G. Oyen +4 more
TL;DR: The technique appears to have significant potential for the characterization of tumors and for the prediction of prognosis in the context of treatment stratification and early assessment of tumor response to therapy.
Journal ArticleDOI
Evidence-based Guideline Recommendations on the Use of Positron Emission Tomography Imaging in Head and Neck Cancer
TL;DR: In this article, the authors provide evidence-based practice guideline recommendations on the use of fluoro-2-deoxy-d-glucose positron emission tomography (PET) for diagnosis, staging, assessing treatment response, liver metastasis and restaging or recurrence of colorectal cancer.
Journal ArticleDOI
Role of FDG PET/CT and chest CT in the follow-up of lung lesions treated with radiofrequency ablation.
Désirée Deandreis,Sophie Leboulleux,Clarisse Dromain,Anne Auperin,Jeremy Coulot,Jean Lumbroso,Frederic Deschamps,Pramod Rao,Martin Schlumberger,Thierry de Baere +9 more
TL;DR: FDG PET/CT can be used for the evaluation of the effectiveness of lung RF ablation and inflammatory FDG uptake in mediastinal lymph nodes or at the needle path puncture site used forRF ablation may occur.
Journal ArticleDOI
Planning transarterial radioembolization of colorectal liver metastases with Yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques.
Timm Denecke,R. Rühl,Bert Hildebrandt,Lars Stelter,Christian Grieser,H. Stiepani,Michael Werk,P. Podrabsky,Michail Plotkin,Holger Amthauer,Jens Ricke,Enrique Lopez Hänninen +11 more
TL;DR: The sequential approach appears to be suitable and keeps the number of unnecessary treatments and therapy risks to a minimum in patients with colorectal liver metastases considered for transarterial radioembolization.
Journal Article
Tailoring therapy in colorectal cancer by PET-CT.
TL;DR: This systematic review aims to provide an up-to-date overview of literature on the current and potential value of FDG-PET in CRC patients by addressing staging and recurrence detection, prognosis and response prediction and evaluation of preoperative (chemo)radiotherapy for primary rectal carcinoma, ablative treatment for unresectable liver metastases and chemotherapy for advanced CRC.
References
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Journal ArticleDOI
Surgical resection of colorectal carcinoma metastases to the liver : A prognostic scoring system to improve case selection, based on 1568 patients
Nordlinger B,Marguerite Guiguet,Jean-Christophe Vaillant,P. Balladur,Karim Boudjema,Philippe Bachellier,Daniel Jaeck +6 more
TL;DR: Five‐year survival rates after resection of liver metastases from colorectal carcinoma are close to 25%, and selection of patients likely to benefit from surgery remains controversial and subjective.
Journal ArticleDOI
Percutaneous radio-frequency ablation of hepatic metastases from colorectal cancer: long-term results in 117 patients.
Luigi Solbiati,Tito Livraghi,S N Goldberg,T. Ierace,Meloni F,M. Dellanoce,Luca Cova,Elkan F. Halpern,G S Gazelle +8 more
TL;DR: RF ablation is an effective method to treat hepatic metastases from colorectal carcinoma and Frequency and time to local recurrence were related to lesion size (P < or =.001).
Journal ArticleDOI
Some practical issues of experimental design and data analysis in radiological ROC studies.
TL;DR: The purposes of this paper are to make users of ROC methodology in medical imaging aware of potential problems that should be confronted before an ROC study is begun and to indicate, at least broadly, how those problems may be dealt with, given the present state of the art.
Journal Article
A meta-analysis of the literature for whole-body FDG PET detection of recurrent colorectal cancer.
Ralf H. Huebner,Kenneth C. Park,J E Shepherd,Judy Schwimmer,Johannes Czernin,Michael E. Phelps,Sanjiv S. Gambhir +6 more
TL;DR: The overall values determined through the meta-analysis indicate the potential benefits of using FDG PET as a diagnostic or management tool and should prove to be useful to assess the cost-effectiveness of usingFDG PET in the management of patients with recurrent CRC.
Journal ArticleDOI
Malignant liver tumors treated with MR imaging-guided laser-induced thermotherapy : technique and prospective results
T. J. Vogl,P K Müller,Renate Hammerstingl,Weinhold N,Martin G. Mack,Philipp C,Michael Deimling,Beuthan J,W. Pegios,H Riess +9 more
TL;DR: MR imaging-guided laser-induced thermotherapy of liver metastases is a safe and promising therapy for liver metastased patients.