Association of Exon 10A and 10B inactivating mutation of follicle stimulating hormone receptor gene (FSHR) and Polycystic Ovarian Syndrome in Vellore cohort
Nishu Sekar,Rucha Kulkarni,Sharvari Ozalkar,Yogamaya D Prabhu,Kaviyarasi Renu,Shalaka S Ramgir,V G Abilash +6 more
- Vol. 263, Iss: 2, pp 022036
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The article was published on 2017-11-01 and is currently open access. It has received 1 citations till now. The article focuses on the topics: Exon & Mutation (genetic algorithm).read more
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Role of TGF-β signalling in PCOS associated focal segmental glomerulosclerosis
Monica Bhati,Yogamaya D Prabhu,Kaviyarasi Renu,Balachandar Vellingiri,Padma Thiagarajan,Aditi Panda,Rituraj Chakraborty,Haritha Myakala,Abilash Valsala Gopalakrishnan +8 more
TL;DR: The role of TGF-β's in PCOS and FSGS is reviewed and the inter-relationship between these two disorders is explored.
References
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Journal ArticleDOI
The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report
Ricardo Azziz,Enrico Carmina,Didier Dewailly,Evanthia Diamanti-Kandarakis,Héctor F. Escobar-Morreale,Walter Futterweit,Onno E. Janssen,Richard S. Legro,Robert J. Norman,Ann Taylor,Selma F. Witchel +10 more
TL;DR: It is the view of the AE-PCOS Society Task Force that PCOS should be defined by the presence of hyperandrogenism, ovarian dysfunction, and/or polycystic ovaries, and the exclusion of related disorders.
Journal ArticleDOI
Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure
Kristiina Aittomäki,Kristiina Aittomäki,JoséLuis Dieguez Lucena,JoséLuis Dieguez Lucena,Pirjo Pakarinen,Pertti Sistonen,Juha S. Tapanainen,Jörg Gromoll,Riitta Kaskikari,Eeva-Marja Sankila,Heikki Lehväslaiho,Armando Reyes Engel,Eberhard Nieschlag,Ilpo Huhtaniemi,Albert de la Chapelle +14 more
TL;DR: It is concluded that a mutation in the follicle-stimulating hormone receptor gene causes hypergonadotropic ovarian dysgenesis in multiplex affected families and that the mutation causes ODG in these families.
Journal ArticleDOI
Diagnosis of Polycystic Ovarian Syndrome: The Rotterdam Criteria Are Premature
TL;DR: Because of the paucity of data on the two new phenotypes and their long-term implications and the potential negative impact on research, clinical practice, and patient insurability, the adoption of the Rotterdam 2003 criteria for defining PCOS should be considered premature.
Journal ArticleDOI
Endothelial dysfunction in PCOS: role of obesity and adipose hormones
Enrico Carmina,Francesco Orio,Stefano Palomba,R A Longo,Teresa Cascella,A. Colao,G. Lombardi,Giovan Battista Rini,Rogerio A. Lobo +8 more
TL;DR: In this paper, the carotid intima-media thickness (IMT) and brachial flow-mediated dilation (FMD) in young women with PCOS may be explained by insulin resistance and elevated adipocytokines.
Journal ArticleDOI
The cloning of the human follicle stimulating hormone receptor and its expression in COS-7, CHO, and Y-1 cells.
Christie A. Kelton,Cheng Shirley Vui Yen,Nugent Noreen P,Rene Lynn Schweickhardt,Judy L. Rosenthal,Susan A. Overton,Gregory D. Wands,Jennifer B. Kuzeja,Carol A. Luchette,Chappel Scott C +9 more
TL;DR: The FSH-responsive CHO and Y-1 cell lines may be suitable for the development of better in vitro FSH bioassays and constitute a convenient source of human FSH receptor protein for use in radioreceptor assays and in studies of receptor-ligand interactions.