Journal ArticleDOI
Barrett's esophagus: development of dysplasia and adenocarcinoma.
TLDR
The results of this study support the need for a long-term clinical, endoscopic, and histologic follow-up program in patients with Barrett's esophagus with an incidence of carcinoma of 1 in 52 patient-years, a 125-fold increase compared with the general Dutch population.About:
This article is published in Gastroenterology.The article was published on 1989-05-01. It has received 869 citations till now. The article focuses on the topics: Barrett's esophagus & Dysplasia.read more
Citations
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Journal ArticleDOI
Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma
TL;DR: There is a strong and probably causal relation between gastroesophageal reflux and esophageaal adenocarcinoma, and the relation between reflux And gastric cardia is relatively weak.
Journal ArticleDOI
Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus.
TL;DR: The guidelines for the diagnosis, surveillance and therapy of Barrett’s esophagus were originally published by the American College of Gastroenterology in 1998 and updated in 2002 and once again reviewed using the National Library of Medicine database.
Journal ArticleDOI
Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial.
Stuart J. Spechler,Edward L. Lee,Dennis J. Ahnen,Raj K. Goyal,Ikuo Hirano,Francisco C. Ramirez,Jean-Pierre Raufman,Richard E. Sampliner,Thomas G. Schnell,Stephen J. Sontag,Z. Reno Vlahcevic,Renee Young,William O. Williford +12 more
TL;DR: This study suggests that antireflux surgery should not be advised with the expectation that patients with GERD will no longer need to take antisecretory medications or that the procedure will prevent esophageal cancer among those with GERd and Barrett esophagus.
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Practice guidelines on the diagnosis, surveillance, and therapy of Barrett's esophagus. The Practice Parameters Committee of the American College of Gastroenterology.
TL;DR: These guidelines are intended to indicate the preferable, but not the only acceptable, approach to this problem, given the wide range of specifics in any health care problem, the physician must always choose the course best suited to the individual patient and the variables in existence at the moment of decision.
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Is there publication bias in the reporting of cancer risk in Barrett's esophagus?
TL;DR: There was a strong correlation between cancer risk and the size of the study, with small studies reporting much higher risks of cancer than larger studies, and publication bias may be overestimated in the literature due to publication bias.
References
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Journal ArticleDOI
Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications
Robert H. Riddell,Harvey Goldman,David F. Ransohoff,Henry D. Appelman,Cecilia M. Fenoglio,Rodger C. Haggitt,Christer hren,Pelayo Correa,Stanley R. Hamilton,B C Morson,Sheldon C. Sommers,John H. Yardley +11 more
TL;DR: A classification system for the epithelial changes that occur in ulcerative colitis was developed, which should be applicable to other forms of inflammatory bowel disease as well and makes use of standardized terminology, addresses specific problem areas, and offers practical solutions.
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Observer variation in the diagnosis of dysplasia in Barrett's esophagus.
Brian J. Reid,Rodger C. Haggitt,Cyrus E. Rubin,G. Roth,Christina M. Surawicz,G. Van Belle,Klaus J. Lewin,Wilfred M. Weinstein,Donald A. Antonioli,Harvey Goldman,W. MacDonald,D. Owen +11 more
TL;DR: It is concluded that experienced gastrointestinal morphologists can diagnose high-grade dysplasia and intramucosal carcinoma with a high degree of agreement and thus can detect those patients who may need immediate rebiopsy or esophageal resection.
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The Incidence of Adenocarcinoma in Columnar-Lined (Barrett's) Esophagus
TL;DR: Although the incidence of esophageal adenocarcinoma is increased in patients with symptomatic Barrett's esophagus, it does not occur in the majority of such patients.
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The Histologic Spectrum of Barrett's Esophagus
TL;DR: Histoligic study of the columnar-lined esophagus demonstrated a spectrum of epithelial patterns, which helps to explain prior discrepant reports.
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Columnar-lined lower esophagus: an acquired lesion with malignant predisposition. Report on 140 cases of Barrett's esophagus with 12 adenocarcinomas.
TL;DR: The analysis of a series of 1,225 cases of reflux esophagitis shows the serious nature of this condition and the transition toward malignancy seems to be irreversible and cannot be arrested by an antireflux operation, so repeated esophageal controls and biopsies are an absolute necessity.