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Journal ArticleDOI

Biomedical optical analytical techniques to analyse the medicinal drugs and optical properties of tissues

TLDR
In this paper, the biomedical optical analytical techniques such as ultra-violet spectroscopy, Fourier transform infrared spectrograms, and Fourier Transform-Raman spectrographs are used to characterise and quantise the medicinal drugs.
Abstract
In this research paper, the biomedical optical analytical techniques such as ultra-violet spectroscopy, Fourier transform infrared spectroscopy and Fourier transform-Raman spectroscopy are used to characterise and quantise the medicinal drugs. The hydroxyl group and methyl group was assigned to the wave numbers 3230.67 cm–1 and 2928.50 cm–1. The functional groups are also identified –N=C=O, –N=C=S, –N=C=N–, –N3 at 4.67 µm. The CH, CH2, and CH3 three bands with strong intensity are assigned to the wave numbers 2985 cm–1 to 2850 cm–1. The FT-Raman spectra is obtained for the blue sample, the functional group C≡C is assigned to the wave number 2129.84 to 2191.41 cm–1. The wave numbers 2558.71–2620.73 cm–1 are obtained for the functional bond –S–H. The wave number 1610.95 cm–1 is obtained for the C=N functional group. In this paper one sample namely Fibril-SF is taken by a patient and his Saliva sample is collected for Fourier Transform Infrared spectroscopy test to analyse the reaction of drugs with human body tissues.

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Nanoparticle analysis for various medicinal drugs and human body saliva at macromolecular level

TL;DR: The spectral bio-diagnosis of normal human body saliva sample shows the following functional compounds and it is related to various proteins and enzymes as mentioned in this paper : the hydroxyl group is observed in the form of O-H at 3,305 cm−1, because of the presence of lipids, the functional group C-H is obtained from 2,928 to 2,856 cm− 1, due to the presence amide-I in the forms of C=N and C=C obtained at 1,658 cm−2, the proteins are exhibited.
Journal ArticleDOI

A model of optimising the needle insertion through deflection studies

TL;DR: This study was the first-step in developing a deflection feedback controlled surgical instrument in the needle-assisted percutaneous operation and provided understanding on the mechanics of needle insertion.
References
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Journal ArticleDOI

Flexible Fiber-Optics Probes for Raman and FT-IR Remote Spectroscopy

TL;DR: In this paper, a hollow fiber probe with a ball lens at the end works as a confocal system for remote Raman and infrared spectroscopy, which can detect the molecular structure of biotissues with a high SNR.
Proceedings ArticleDOI

Low cost video endoscopes with simplified integration

TL;DR: This work proposes system designs and prototypes for f/4, 3mm outer diameter endoscopes with 70° and 110° field of view using a CMOS imager with 650x650 pixels of 2.8μm pitch allowing for high performance paired with low fabrication cost allowing for the usage as a disposable unit.
Proceedings ArticleDOI

Fundamental performances of a micro stationary Fourier transform spectrometer

TL;DR: In this paper, a new configuration of micro-spectrometer based on an infrared stationary Fourier transform (FTIR) interferometer has been developed at ONERA, and the results of this theoretical study are exploited to design a compact spectrometer with a very simple optical architecture.
Journal ArticleDOI

Nonlinear optical spectroscopy on polysilanes: dependence of exciton states on backbone conformations

TL;DR: In this paper, the third-order nonlinear optical susceptibility χ (3) (-3ω;ω,ω, ω) has been measured on spin-coated films of three kinds of polysilanes (PS's) with various backbone conformations, in a wide range of fundamental wavelength, by means of third-harmonic generation (THG) measurement.
Proceedings ArticleDOI

Towards an improved assignment of spectral features in tissue modulated non-invasive Raman spectroscopy of human fingertips

TL;DR: In this article, a new LighTouch TM device has been constructed to measure and control applied force and tissue position in noninvasive probing of human volar side fingertip capillary beds in vivo using near infrared Ramanormal spectroscopy.
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