Biomimetic Hydroxyapatite Coating on Metal Implants
TLDR
In this paper, a biomimetic coating was applied on titanium and porous-tantalum implants to facilitate rapid bone formation around the implant, reducing therewith the patient's recovery time after surgery.Abstract:
The combination of the high mechanical strength of metals with the osteoconductive properties of calcium phosphates make hydroxyapatite coatings on titanium implants widely used in orthopedic surgery However, the most popular coating method, plasma spraying, exhibits some important drawbacks: the inability to cover porous implants and to incorporate biologically active agents, delamination, and particle release The aim of this study was to elaborate a dense, strong, and thick calcium-phosphate coating on titanium and porous-tantalum implants using a two-step biomimetic procedure In the first step, the implants were soaked in a solution that was 5 times more concentrated than regular simulated body fluid (SBF-A solution) A thin but uniform amorphous calcium-phosphate coating was deposited on the metal Then, the implants were immersed in the SBF-B solution, which had a similar composition as the SBF-A solution, but with decreased contents of crystal growth inhibitors (ie, Mg2+ and HCO3−) This resulted in the fast precipitation of a 30 μm thick crystalline calcium-phosphate coating The pH of the SBF-B solution and the thickness of the crystalline coating layer were studied as a function of time The Fourier transform infrared spectra and X-ray diffraction patterns showed that this new coating closely resembles bone mineral Our biomimetic coating should facilitate rapid bone formation around the implant, reducing therewith the patient's recovery time after surgeryread more
Citations
More filters
Journal ArticleDOI
Magnesium and its alloys as orthopedic biomaterials: a review.
TL;DR: A review of the properties, biological performance, challenges and future directions of magnesium-based biomaterials can be found in this paper, where the authors explore the properties and challenges of magnesium biomaterial.
Journal ArticleDOI
Surface treatments of titanium dental implants for rapid osseointegration
TL;DR: The local release of bone stimulating or resorptive drugs in the peri-implant region may also respond to difficult clinical situations with poor bone quality and quantity, which should ultimately enhance the osseointegration process of dental implants for their immediate loading and long-term success.
Journal ArticleDOI
Calcium phosphates as substitution of bone tissues
TL;DR: In this paper, a review of the role played by biological calcium phosphates in bone regeneration is presented, where the synthesis procedures to obtain in the laboratory calcium deficient carbonate nanoapatite both in bulk and thin film forms, as well as the characterization methods applied to these materials are described.
Journal ArticleDOI
Biomimetic Systems for Hydroxyapatite Mineralization Inspired By Bone and Enamel
Liam C. Palmer,Christina J. Newcomb,Stuart R. Kaltz,Erik David Spoerke,Erik David Spoerke,Samuel I. Stupp +5 more
TL;DR: This review focuses on the formation of hydroxyapatite in synthetic systems designed primarily in the biomimetic context of bone or enamel mineralization for therapeutic approaches in repair of human tissues.
Journal ArticleDOI
Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
References
More filters
Journal ArticleDOI
Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W.
TL;DR: The results support the concept that the apatite phase on the surface of glass-ceramic A-W is formed by a chemical reaction of the glass- Aceramic with the Ca2+, HPO4(2-), and OH- ions in the body fluid.
Book
Structure and chemistry of the apatites and other calcium orthophosphates
TL;DR: In this paper, the authors describe the structure of carbonate apatites and the properties of apatite powders, including their properties in terms of their nucleation and crystal growth.
Journal ArticleDOI
Preparation of bioactive Ti and its alloys via simple chemical surface treatment.
TL;DR: The present chemical surface modification is expected to allow the use the bioactive Ti and its alloys as artificial bones even under load-bearing conditions.
Journal ArticleDOI
The Norwegian Arthroplasty Register: 11 years and 73,000 arthroplasties.
Leif Ivar Havelin,Lars B. Engesæter,Birgitte Espehaug,Ove Furnes,Stein Atle Lie,Stein Emil Vollset +5 more
TL;DR: Compared the results of primary cemented and uncemented hip pros theses in patients less than 60 years of age, with 0-11 years' follow-up, it is found that cemented cups had better survival than uncements porous-coated cups, mainly because of higher rates of revision from wear and osteolysis among the latter.
Journal ArticleDOI
Structural analysis of hydroxyapatite coatings on titanium.
TL;DR: Depending upon the deposition conditions various changes in the structure of the ceramic were identified and Hydroxyapatite oxygenated to various degrees and tetracalcium phosphate were reproducibly formed in the coating.