Journal ArticleDOI
Biopsy Schemes with the Fewest Cores for Detecting 95% of the Prostate Cancers Detected by a 24-Core Biopsy
Vincenzo Scattoni,Marco Raber,Firas Abdollah,Marco Roscigno,Federico Dehò,D. Angiolilli,Carmen Maccagnano,Andrea Gallina,Umberto Capitanio,Massimo Freschi,Claudio Doglioni,Patrizio Rigatti,Francesco Montorsi +12 more
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TLDR
A user-friendly flowchart is proposed to identify the most advantageous set of sampling sites according to patients' characteristics and revealed that the most beneficial scheme varied according to the clinical characteristics of the patients.About:
This article is published in European Urology.The article was published on 2010-01-01. It has received 105 citations till now. The article focuses on the topics: Prostate biopsy & Biopsy.read more
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Journal ArticleDOI
Contemporary Role of Systematic Prostate Biopsies: Indications, Techniques, and Implications for Patient Care
Osamu Ukimura,Osamu Ukimura,Jonathan A. Coleman,Alex de la Taille,Mark Emberton,Mark Emberton,Jonathan I. Epstein,Stephen J. Freedland,Gianluca Giannarini,Adam S. Kibel,Rodolfo Montironi,Guillaume Ploussard,Monique J. Roobol,Vincenzo Scattoni,J. Stephen Jones +14 more
TL;DR: Current data support the utility of extended PB templates for initial TRUS PB intended to detect clinically significant PCa, and debate continues regarding indications, sampling number, and location as well as on the potential of modern image-guided approaches or three-dimensional mapping biopsy in this unique setting.
Journal ArticleDOI
Multiparametric magnetic resonance imaging vs. standard care in men being evaluated for prostate cancer: a randomized study
Valeria Panebianco,Flavio Barchetti,Alessandro Sciarra,Antonio Ciardi,Elena Lucia Indino,Rocco Papalia,Michele Gallucci,Vincenzo Tombolini,Vincenzo Gentile,Carlo Catalano +9 more
TL;DR: In this article, the proportion of men with clinically significant prostate cancer (PCa) is higher among men randomized to multiparametric magnetic resonance imaging (mp-MRI)/biopsy vs. those randomized to transrectal ultrasound (TRUS)-guided biopsy.
Journal ArticleDOI
Prostate-Specific Antigen (PSA) Isoform p2PSA Significantly Improves the Prediction of Prostate Cancer at Initial Extended Prostate Biopsies in Patients with Total PSA Between 2.0 and 10 ng/ml: Results of a Prospective Study in a Clinical Setting
Giorgio Guazzoni,Luciano Nava,Massimo Lazzeri,Vincenzo Scattoni,Giovanni Lughezzani,Carmen Maccagnano,Fernanda Dorigatti,Ferruccio Ceriotti,Marina Pontillo,Vittorio Bini,Massimo Freschi,Francesco Montorsi,Patrizio Rigatti +12 more
TL;DR: In patients with a tPSA between 2.0 and 10 ng/ml, %p2PSA and phi are the strongest predictors of PCa at initial extended biopsies and are significantly more accurate than the currently used tests (tPSA, %f PSA, and PSAD) in determining the presence ofPCa at biopsy.
Journal ArticleDOI
Development and Internal Validation of a Novel Model to Identify the Candidates for Extended Pelvic Lymph Node Dissection in Prostate Cancer.
Giorgio Gandaglia,Nicola Fossati,Emanuele Zaffuto,Marco Bandini,Paolo Dell'Oglio,Carlo Andrea Bravi,Giuseppe Fallara,Francesco Pellegrino,Luigi Nocera,Pierre I. Karakiewicz,Zhe Tian,Massimo Freschi,Rodolfo Montironi,Francesco Montorsi,Alberto Briganti +14 more
TL;DR: A lymph node dissection exclusively in men with a risk of LNI >7% according to this model would significantly reduce the number of unnecessary pelvic nodal dissections with arisk of missing only 1.5% of patients with LNI.
Journal ArticleDOI
How reliable is 12-core prostate biopsy procedure in the detection of prostate cancer?
Ege Can Serefoglu,Serkan Altinova,Nevzat Serdar Ugras,Egemen Akincioglu,Erem Asil,M. Derya Balbay +5 more
TL;DR: The detection rate of prostate cancer with 12-core prostate biopsy in patients (all of whom had prostate cancer) was considerably low, meaning that repeat biopsies can still be negative despit the patient’s reality of having prostate cancer.
References
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Journal ArticleDOI
Classification and Regression Trees.
Journal ArticleDOI
Classification and regression trees
TL;DR: This article gives an introduction to the subject of classification and regression trees by reviewing some widely available algorithms and comparing their capabilities, strengths, and weakness in two examples.
Book
Classification and regression trees
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI
Diagnostic Value of Systematic Biopsy Methods in the Investigation of Prostate Cancer: A Systematic Review
TL;DR: In this paper, the authors compared the cancer detection rates and complications of different extended prostate biopsy (greater than 6 cores) schemes for diagnostic evaluation in men scheduled for biopsy to identify the optimal scheme.
Diagnostic Value of Systematic Biopsy Methods in the Investigation of Prostate Cancer
TL;DR: Prostate biopsy schemes consisting of 12 cores that add laterally directed cores to the standard sextant scheme strike the balance between the cancer detection rate and adverse events.