Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2007 update.
Denis E. O'Donnell,Shawn D. Aaron,Jean Bourbeau,Paul Hernandez,Darcy D Marciniuk,Meyer Balter,Gordon T. Ford,Andre Gervais,Roger S. Goldstein,Rick Hodder,Alan Kaplan,Sean P. Keenan,Yves Lacasse,François Maltais,Jeremy Road,Graeme Rocker,Don D. Sin,Tasmin Sinuff,Nha Voduc +18 more
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Highlights of this update include new epidemiological information on mortality and prevalence of COPD, which charts its emergence as a major health problem for women; a new section on common comorbidities in COPD; and an increased emphasis on the meaningful benefits of combined pharmacological and nonpharmacological therapies.Abstract:
Chronic obstructive pulmonary disease (COPD) is a major respiratory illness in Canada that is both preventable and treatable Our understanding of the pathophysiology of this complex condition continues to grow and our ability to offer effective treatment to those who suffer from it has improved considerably The purpose of the present educational initiative of the Canadian Thoracic Society (CTS) is to provide up to date information on new developments in the field so that patients with this condition will receive optimal care that is firmly based on scientific evidence Since the previous CTS management recommendations were published in 2003, a wealth of new scientific information has become available The implications of this new knowledge with respect to optimal clinical care have been carefully considered by the CTS Panel and the conclusions are presented in the current document Highlights of this update include new epidemiological information on mortality and prevalence of COPD, which charts its emergence as a major health problem for women; a new section on common comorbidities in COPD; an increased emphasis on the meaningful benefits of combined pharmacological and nonpharmacological therapies; and a new discussion on the prevention of acute exacerbations A revised stratification system for severity of airway obstruction is proposed, together with other suggestions on how best to clinically evaluate individual patients with this complex disease The results of the largest randomized clinical trial ever undertaken in COPD have recently been published, enabling the Panel to make evidence-based recommendations on the role of modern pharmacotherapy The Panel hopes that these new practice guidelines, which reflect a rigorous analysis of the recent literature, will assist caregivers in the diagnosis and management of this common conditionread more
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Development and first validation of the COPD Assessment Test
TL;DR: The aim of the present study was to develop a short validated patient-completed questionnaire, the COPD Assessment Test (CAT), assessing the impact of COPD on health status, which has good measurement properties, is sensitive to differences in state and should provide a valid, reliable and standardised measure of COPd health status with worldwide relevance.
Journal ArticleDOI
Pulmonary rehabilitation for chronic obstructive pulmonary disease
TL;DR: In four important domains of quality of life (QoL) (Chronic Respiratory Questionnaire (CRQ) scores for dyspnoea, fatigue, emotional function and mastery), the effect was larger than the minimal clinically important difference (MCID) of 0.4%.
Journal ArticleDOI
Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial.
Shawn D. Aaron,Katherine L. Vandemheen,Dean Fergusson,François Maltais,Jean Bourbeau,Roger S. Goldstein,Meyer Balter,Denis E. O'Donnell,Andrew McIvor,Sat Sharma,Graham Bishop,John Anthony,Robert L. Cowie,Stephen K. Field,Andrew Hirsch,Paul Hernandez,R. N. Rivington,Jeremy Road,Victor Hoffstein,Richard V. Hodder,Darcy D Marciniuk,David G. McCormack,George A Fox,Gerard Cox,Henry B. Prins,Gordon T. Ford,Dominique Bleskie,Steve Doucette,Irvin Mayers,Kenneth R. Chapman,Noe Zamel,Mark FitzGerald +31 more
TL;DR: A randomized, double-blind, placebo-controlled clinical trial to determine whether combining tiotropium with salmeterol or fluticasonesalmeterol produces greater improvements in clinical outcomes for adults with moderate or severe COPD compared with tiotopium therapy alone.
Journal ArticleDOI
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials
Leonardo M. Fabbri,Peter M.A. Calverley,José Luis Izquierdo-Alonso,Daniela S. Bundschuh,Manja Brose,Fernando J. Martinez,Klaus F. Rabe +6 more
TL;DR: Roflumilast improves lung function in patients with COPD treated with salmeterol or tiotropium, and could become an important treatment for these patients.
Journal ArticleDOI
An Official American Thoracic Society/European Respiratory Society Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation
Carolyn L. Rochester,Ioannis Vogiatzis,Anne E Holland,Suzanne C. Lareau,Darcy D Marciniuk,Milo A. Puhan,Martijn A. Spruit,Sarah Masefield,Richard Casaburi,Enrico Clini,Rebecca Crouch,Judith Garcia-Aymerich,Chris Garvey,Roger S. Goldstein,Kylie Hill,Mike Morgan,Linda Nici,Fabio Pitta,Andrew L. Ries,Sally J Singh,Thierry Troosters,Peter J. Wijkstra,Barbara P. Yawn,Richard ZuWallack +23 more
TL;DR: This document articulates policy recommendations for advancing healthcare professional, payer, and patient awareness and knowledge of PR, increasing patient access to PR, and ensuring quality of PR programs.
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Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
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TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
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Interpretative strategies for lung function tests
Riccardo Pellegrino,Giovanni Viegi,Vito Brusasco,Robert O. Crapo,Felip Burgos,Richard Casaburi,Allan L. Coates,C.P.M. van der Grinten,P. Gustafsson,John L. Hankinson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Martin R. Miller,Daniel Navajas,O. F. Pedersen,J. Wanger +17 more
TL;DR: This section is written to provide guidance in interpreting pulmonary function tests (PFTs) to medical directors of hospital-based laboratories that perform PFTs, and physicians who are responsible for interpreting the results of PFTS most commonly ordered for clinical purposes.
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Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper
Bartolome R. Celli,William MacNee,Alvar Agusti,Antonio Anzueto,B. Berg,A. S. Buist,Peter M.A. Calverley,Niels H. Chavannes,T. Dillard,Bonnie F. Fahy,Alan M. Fein,John E. Heffner,Suzanne C. Lareau,Paula Meek,Fernando J. Martinez,Walter T. McNicholas,Jean W M Muris,E. Austegard,Romain Pauwels,S. I. Rennard,Adriano G. Rossi,NM Siafakas,B. Tiep,Jørgen Vestbo,E. F. M. Wouters,Richard ZuWallack +25 more
TL;DR: The main goals of the updated document are to improve the quality of care provided to patients with COPD and to develop the project using a disease-oriented approach.
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Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper
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