D
Dean Fergusson
Researcher at Ottawa Hospital Research Institute
Publications - 725
Citations - 38672
Dean Fergusson is an academic researcher from Ottawa Hospital Research Institute. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 90, co-authored 655 publications receiving 32781 citations. Previous affiliations of Dean Fergusson include Children's Hospital of Eastern Ontario & Université de Montréal.
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Journal ArticleDOI
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Andrew I R Maas,David K. Menon,P. David Adelson,Nada Andelic,Michael J. Bell,Antonio Belli,Peter Bragge,Alexandra Brazinova,Andras Buki,Randall M. Chesnut,Giuseppe Citerio,Mark Coburn,D. Jamie Cooper,A Tamara Crowder,Endre Czeiter,Marek Czosnyka,Ramon Diaz-Arrastia,Jens P. Dreier,Ann-Christine Duhaime,Ari Ercole,Thomas A. van Essen,Valery L. Feigin,Guoyi Gao,Joseph T. Giacino,Laura E. Gonzalez-Lara,Russell L. Gruen,Russell L. Gruen,Deepak Gupta,Jed A. Hartings,Sean Hill,Jiyao Jiang,Naomi Ketharanathan,Erwin J. O. Kompanje,Linda Lanyon,Steven Laureys,Fiona Lecky,Harvey S. Levin,Hester F. Lingsma,Marc Maegele,Marek Majdan,Geoffrey T. Manley,Jill A. Marsteller,Luciana Mascia,Charles McFadyen,Stefania Mondello,Virginia F. J. Newcombe,Aarno Palotie,Aarno Palotie,Aarno Palotie,Paul M. Parizel,Wilco C. Peul,James Piercy,Suzanne Polinder,Louis Puybasset,Todd E. Rasmussen,Rolf Rossaint,Peter Smielewski,Jeannette Söderberg,Simon J. Stanworth,Murray B. Stein,Nicole von Steinbüchel,William Stewart,Ewout W. Steyerberg,Ewout W. Steyerberg,Nino Stocchetti,Anneliese Synnot,Anneliese Synnot,Braden Te Ao,Olli Tenovuo,Alice Theadom,Dick Tibboel,Walter Videtta,Kevin K.W. Wang,W. Huw Williams,Lindsay Wilson,Kristine Yaffe,Hadie Adams,Vanni Agnoletti,Judith Allanson,Krisztina Amrein,Norberto Andaluz,Audny Anke,Anna Antoni,Arjan Bastiaan van As,Gérard Audibert,Antun Azaševac,Philippe Azouvi,Maria Luisa Azzolini,Camelia Baciu,Rafael Badenes,Karen M. Barlow,Ronald H. M. A. Bartels,Ursula Bauerfeind,Miriam H. Beauchamp,Darcy Beer,Ronny Beer,Francisco Javier Belda,Bo-Michael Bellander,Rémy Bellier,Habib Benali,Thierry Benard,Valzerda Beqiri,Luigi Beretta,Francis Bernard,Guido Bertolini,Federico Bilotta,Morten Blaabjerg,Hugo den Boogert,Kathy Boutis,Pierre Bouzat,Brian L. Brooks,Camilla Brorsson,Monika Bullinger,Emma Burns,Calappi E,Peter Cameron,Elsa Carise,Ana M. Castaño-Leon,Francesco Causin,Giorgio Chevallard,Arturo Chieregato,Brian R. Christie,Maryse C. Cnossen,Jonathan P. Coles,Johnny Collett,Francesco Della Corte,William Craig,Gábor Csató,Ákos Csomós,Nicola Curry,Claire Dahyot-Fizelier,Helen Dawes,Carol DeMatteo,Bart Depreitere,Deborah Dewey,Jeroen T. J. M. van Dijck,Đula Đilvesi,Diederik W.J. Dippel,Kemal Dizdarevic,Emma Donoghue,Or Duek,Guy-Loup Dulière,Adelaida Dzeko,George A. Eapen,Carolyn A. Emery,Shane W. English,Patrick Esser,Erzsébet Ezer,Martin Fabricius,Junfeng Feng,Dean Fergusson,Anthony Figaji,Joanne Fleming,Kelly A Foks,G. Francony,Stephen B. Freedman,Ulderico Freo,Shirin Frisvold,Isabelle Gagnon,Damien Galanaud,Dashiell Gantner,Benoit Giraud,Ben Glocker,Jagos Golubovic,Pedro A Gómez López,Wayne A. Gordon,Primoz Gradisek,Jocelyn Gravel,Donald E. G. Griesdale,Francesca Grossi,Juanita A. Haagsma,Asta Håberg,Iain K. Haitsma,Wim Van Hecke,Raimund Helbok,Eirik Helseth,Caroline M. van Heugten,Cornelia W. E. Hoedemaekers,Stefan Höfer,Lindsay Horton,Jiyuan Hui,Jilske A Huijben,Peter J. Hutchinson,Bram Jacobs,Mathieu van der Jagt,Stefan Jankowski,Koen Janssens,Bojan Jelaca,Kelly Jones,Konstantinos Kamnitsas,Rafael Kaps,Mladen Karan,Ari Katila,Kirsi-Maija Kaukonen,Véronique De Keyser,Riku Kivisaari,Angelos G. Kolias,Balint Kolumban,Ksenija Kolundžija,Daniel Kondziella,Lars-Owe D. Koskinen,Noémi Kovács,Andreas H. Kramer,Demitri Kutsogiannis,Theodoros Kyprianou,Alfonso Lagares,Francois Lamontagne,Roberto Latini,François Lauzier,Isaac Lazar,Christian Ledig,Rolf Lefering,Valerie Legrand,Leon Levi,Roger Lightfoot,Angels Lozano,Stephen MacDonald,Sebastian Major,Alex Manara,Pauline Manhes,Hugues Maréchal,Costanza Martino,Alessandro Masala,Serge Masson,Julia Mattern,Bradford J. McFadyen,Catherine McMahon,Maureen O. Meade,Béla Melegh,Tomas Menovsky,Lynne Moore,Marta M Correia,Maria Cristina Morganti-Kossmann,Holger Muehlan,Pratik Mukherjee,Lynnette Murray,Joukje van der Naalt,Ancuta Negru,David W. Nelson,Daan Nieboer,Quentin Noirhomme,József Nyirádi,Mauro Oddo,David O. Okonkwo,Annemarie W. Oldenbeuving,Fabrizio Ortolano,Martin H. Osmond,Jean-François Payen,Vincent Perlbarg,Paolo Persona,Nicolas Pichon,Anna Piippo-Karjalainen,Sebastien Pili-Floury,Matti Pirinen,Horia Ple,Maria A. Poca,Jussi P. Posti,Dominique Van Praag,Alain Ptito,Andreea Radoi,Arminas Ragauskas,Arminas Ragauskas,Rahul Raj,Ruben G. L. Real,Nick Reed,Jonathan Rhodes,Claudia S. Robertson,Saulius Rocka,Saulius Rocka,Cecilie Røe,Olav Røise,Gerwin Roks,Jonathan Rosand,Jeffrey V. Rosenfeld,Christina Rosenlund,Guy Rosenthal,Sandra Rossi,Daniel Rueckert,Godard C.W. de Ruiter,Marco Sacchi,Barbara J. Sahakian,Juan Sahuquillo,Oliver W. Sakowitz,Gerardo Salvato,Renán Sánchez-Porras,János Sándor,Grinder Sangha,Nadine Schäfer,Silke Schmidt,Kathryn J Schneider,David M. Schnyer,Herbert Schöhl,Guus G. Schoonman,Rico Frederik Schou,Özcan Sir,Toril Skandsen,Dirk Smeets,Abayomi Sorinola,Emmanuel Stamatakis,Ana Stevanovic,Robert Stevens,Nina Sundström,Fabio Silvio Taccone,Fabio Silvio Taccone,Riikka S.K. Takala,Päivi Tanskanen,Mark Taylor,Ralph Telgmann,Nancy R. Temkin,Guido Teodorani,Matthew Thomas,Christos M. Tolias,Tony Trapani,Alexis F. Turgeon,Peter Vajkoczy,Alex B. Valadka,Egils Valeinis,Shirley Vallance,Zoltan Vamos,Alessia Vargiolu,Emmanuel Vega,Jan Verheyden,Anne Vik,Rimantas Vilcinis,Carmen L.A. Vleggeert-Lankamp,Lidia Vogt,Victor Volovici,Daphne C. Voormolen,Peter Vulekovic,Thijs Vande Vyvere,Julia Van Waesberghe,Lars Wessels,Eno Wildschut,Guy B. Williams,Maren K.L. Winkler,Stefan Wolf,Gordon Wood,Nektaria Xirouchaki,Alexander Younsi,Menashe Zaaroor,Veronika Zelinkova,Roger Zemek,Fabrizio Zumbo +342 more
TL;DR: The InTBIR Participants and Investigators have provided informed consent for the study to take place in Poland.
Journal ArticleDOI
A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery
Dean Fergusson,Paul C. Hébert,C. David Mazer,Stephen E. Fremes,Charles MacAdams,John M. Murkin,Kevin Teoh,Peter C. Duke,Ramiro Arellano,Morris A. Blajchman,Jean S. Bussières,Dany Côté,Jacek Karski,Raymond Martineau,James A. Robblee,Marc A. Rodger,George A. Wells,Jennifer J. Clinch,Roanda Pretorius +18 more
TL;DR: Despite the possibility of a modest reduction in the risk of massive bleeding, the strong and consistent negative mortality trend associated with aprotinin, as compared with the lysine analogues, precludes its use in high-risk cardiac surgery.
Reference EntryDOI
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
David Henry,Paul A. Carless,Annette J Moxey,Dianne L. O'Connell,Barrie Stokes,Dean Fergusson,Katharine Ker +6 more
TL;DR: Data from the head-to-head trials suggest an advantage of aprotinin over the lysine analogues TXA and EACA in terms of reducing perioperative blood loss, but the differences were small.
Journal ArticleDOI
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion.
Jeffrey L. Carson,Simon J. Stanworth,Nareg Roubinian,Dean Fergusson,Darrell J. Triulzi,Carolyn Doree,Paul C. Hébert +6 more
TL;DR: The limited published evidence supports the use of restrictive transfusion triggers in patients who are free of serious cardiac disease, however, most of the data on clinical outcomes were generated by a single trial.
Journal ArticleDOI
Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials
Manoj M. Lalu,Lauralyn McIntyre,Lauralyn McIntyre,Christina Pugliese,Dean Fergusson,Brent W. Winston,John C. Marshall,John Granton,Duncan J. Stewart,Duncan J. Stewart +9 more
TL;DR: Based on the current clinical trials, MSC therapy appears safe, however, further larger scale controlled clinical trials with rigorous reporting of adverse events are required to further define the safety profile of MSCs.