Journal ArticleDOI
Cannabinoid Type 1 Receptors in the Basolateral Amygdala Regulate ACPA-Induced Place Preference and Anxiolytic-Like Behaviors
Tomohiro Tokutake,Takashi Asano,Hajime Miyanishi,Shigetoshi Nakaya,Naotaka Izuo,Atsumi Nitta +5 more
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TLDR
It is suggested that CB1R in the BLA contributes to behavior disorders caused by the acute or chronic use of cannabis.About:
This article is published in Neurochemical Research.The article was published on 2022-08-19. It has received 5 citations till now. The article focuses on the topics: Medicine & Basolateral amygdala.read more
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Sleep disturbance after cessation of cannabis administration in mice.
Takashi Asano,Hiroki Takemoto,Tomoya Horita,Tomohiro Tokutake,Naotaka Izuo,Takatoshi Mochizuki,Atsumi Nitta +6 more
TL;DR: In this article , the authors investigated sleep alterations in mice after the cessation of arachidonylcyclopropylamide (ACPA), a cannabinoid type 1 receptor agonist, administration.
Journal ArticleDOI
Women are taking the hit: Examining the unique consequences of cannabis use across the female lifespan
Erin L. Gräfe,Hannah M.O. Reid,Irene Shkolnikov,Kathlyn Conway,Ayano Kit,Cuero Acosta,Brian R. Christie +6 more
TL;DR: In this article , the authors discuss the prevalence of cannabis use and CUD in women throughout their lifespan and provide a balanced prospective on the positive and negative consequences of using cannabis use, highlighting the necessity for continued research that goes beyond sex differences.
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Shati/Nat8l Overexpression Improves Cognitive Decline by Upregulating Neuronal Trophic Factor in Alzheimer’s Disease Model Mice
Kakeru Chino,Naotaka Izuo,H Noike,Kyosuke Uno,Tomoharu Kuboyama,Chihiro Tohda,Shin-ichi Muramatsu,Atsumi Nitta +7 more
TL;DR: Results suggest that Shati/Nat8l overexpression prevents cognitive dysfunction in 5XFAD mice, indicating that Shatisati/ Nat8l could be a therapeutic target for AD.
Journal ArticleDOI
CB1R chronic intermittent pharmacological activation facilitates amphetamine seeking and self-administration and changes in CB1R/CRFR1 expression in the amygdala and nucleus accumbens in rats
Rodolfo Sánchez-Zavaleta,Alejandra E. Ruiz-Contreras,Andrea Herrera-Solís,Mónica Méndez-Díaz,Miguel Pérez de la Mora,Oscar Prospéro-García +5 more
TL;DR: In this article , the effect of continuous low amounts with intermittent higher amounts of Arachidonyl-chloro-ethylamide (ACEA), a CB1R agonist, on amphetamine seeking and ingestion was compared.
References
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Journal ArticleDOI
Emotion Circuits in the Brain
TL;DR: The field of neuroscience has, after a long period of looking the other way, again embraced emotion as an important research area, and much of the progress has come from studies of fear, and especially fear conditioning as mentioned in this paper.
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Structure of a cannabinoid receptor and functional expression of the cloned cDNA
TL;DR: The cloning and expression of a complementary DNA that encodes a G protein-coupled receptor that is involved in cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana are suggested.
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Molecular characterization of a peripheral receptor for cannabinoids
TL;DR: The cloning of a receptor for cannabinoids is reported that is not expressed in the brain but rather in macrophages in the marginal zone of spleen, which helps clarify the non-psychoactive effects of cannabinoids.
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Neurocircuitry of Addiction
George F. Koob,Nora D. Volkow +1 more
TL;DR: The delineation of the neurocircuitry of the evolving stages of the addiction syndrome forms a heuristic basis for the search for the molecular, genetic, and neuropharmacological neuroadaptations that are key to vulnerability for developing and maintaining addiction.
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Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study
TL;DR: The results suggest that the presently characterized cannabinoid receptor mediates physiological and behavioral effects of natural and synthetic cannabinoids, because it is strongly coupled to guanine nucleotide regulatory proteins and is discretely localized to cortical, basal ganglia, and cerebellar structures involved with cognition and movement.