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Sean Munro
Researcher at Laboratory of Molecular Biology
Publications - 114
Citations - 25608
Sean Munro is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Golgi apparatus & Rab. The author has an hindex of 64, co-authored 110 publications receiving 23949 citations. Previous affiliations of Sean Munro include University of Cambridge & Harvard University.
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Journal ArticleDOI
Molecular characterization of a peripheral receptor for cannabinoids
TL;DR: The cloning of a receptor for cannabinoids is reported that is not expressed in the brain but rather in macrophages in the marginal zone of spleen, which helps clarify the non-psychoactive effects of cannabinoids.
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A C-terminal signal prevents secretion of luminal ER proteins
Sean Munro,Hugh R.B. Pelham +1 more
TL;DR: It is proposed that the KDEL sequence marks proteins that are to be retained in the ER and discuss possible retention mechanisms.
Journal ArticleDOI
Global Mapping of the Yeast Genetic Interaction Network
Amy Hin Yan Tong,Guillaume Lesage,Gary D. Bader,Huiming Ding,Hong Xu,Xiaofeng Xin,James D. Young,Gabriel F. Berriz,Renee L. Brost,Michael Chang,Yiqun Chen,Xin Cheng,Gordon Chua,Helena Friesen,Debra S. Goldberg,Jennifer Haynes,Christine Humphries,Grace He,Shamiza Hussein,Lizhu Ke,Nevan J. Krogan,Zhijian Li,Joshua N. Levinson,Hong Lu,Patrice Menard,Christella Munyana,Ainslie B. Parsons,Owen Ryan,Raffi Tonikian,Tania Michelle Roberts,Anne-Marie Sdicu,Jesse Shapiro,Bilal N. Sheikh,Bernhard Suter,Sharyl L. Wong,Lan V. Zhang,Hongwei Zhu,Christopher G. Burd,Sean Munro,Chris Sander,Jasper Rine,Jack Greenblatt,Matthias Peter,Anthony Bretscher,Graham Bell,Frederick P. Roth,Grant W. Brown,Brenda J. Andrews,Howard Bussey,Charles Boone +49 more
TL;DR: Because digenic interactions are common in yeast, similar networks may underlie the complex genetics associated with inherited phenotypes in other organisms.
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Lipid Rafts: Elusive or Illusive?
TL;DR: There has been considerable recent interest in the possibility that the plasma membrane contains lipid "rafts," microdomains enriched in cholesterol and sphingolipids, and it seems that a definitive proof of raft existence has yet to be obtained.
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An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein.
Sean Munro,Hugh R.B. Pelham +1 more
TL;DR: A cDNA clone is characterized that encodes a protein related to the 70 kd heat shock protein, but is expressed in normal rat liver, and it is identical with two previously described proteins: GRP78, whose synthesis is induced by glucose starvation, and BiP, which is found bound to immunoglobulin heavy chains in pre-B cells.