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Carbohydrates in fish nutrition: effects on growth, glucose metabolism and hepatic enzymes

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TLDR
The focus then shifts to selected aspects of hormonal regulation of carbohydrate metabolism and dietary carbohydrates and their variable effects on glycogen and glucose turnover, and the correlation of dietary carbohydrates with fish health.
Abstract
The utilisation of dietary carbohydrates and their effects on fish metabolism are reviewed. Details on how dietary carbohydrates affect growth, feed utilisation and deposition of nutrients are discussed. Variations in plasma glucose concentrations emphasizing results from glucose tolerance tests, and the impact of adaptation diets are interpreted in the context of secondary carbohydrate metabolism. Our focus then shifts to selected aspects of hormonal regulation of carbohydrate metabolism and dietary carbohydrates and their variable effects on glycogen and glucose turnover. We analyse the interaction of carbohydrates with other nutrients, especially protein and protein sparing, and de novo synthesis of lipids, and finish by discussing the correlation of dietary carbohydrates with fish health.

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Fantastically plastic: fish larvae equipped for a new world

TL;DR: This review looks at advances in molecular phylogeny, endocrine and nutrient influences and long-term studies of the phenotypes of commercially important fish to put the sources and consequences of this plasticity into context.
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Dietary carbohydrate/lipid ratios affect stress, oxidative status and non-specific immune responses of fingerling blunt snout bream, Megalobrama amblycephala

TL;DR: The results of this study indicated that high dietary lipid may cause metabolic stress of fingerling blunt snout bream, as might consequently lead to the elevated liver oxidation rates, impaired liver function, depressed immunity and reduced resistance to A. hydrophila infection of this species.
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Effects of dietary carbohydrate/lipid ratios on non-specific immune responses, oxidative status and liver histology of juvenile yellow catfish Pelteobagrus fulvidraco

TL;DR: The results indicated that the leucocyte count, plasma globulin content and lysozyme activity of fish fed the 5.58 CHO:L diet were significantly significantly higher than the control diet.
Journal ArticleDOI

Insulin regulates the expression of several metabolism-related genes in the liver and primary hepatocytes of rainbow trout (Oncorhynchus mykiss).

TL;DR: It is demonstrated that insulin possesses the intrinsic ability to regulate hepatic gene expression in rainbow trout, suggesting that other hormonal or metabolic factors may counteract some of the post-prandial actions of insulin.
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Microalga Phaeodactylum tricornutum in feed for Atlantic salmon (Salmo salar) —Effect on nutrient digestibility, growth and utilization of feed

TL;DR: Investigating the potential use of the phototrophic microalgae Phaeodactylum tricornutum as a fish meal replacement in diet for Atlantic salmon showed that P. tricORNutum can replace up to 6% of the fish meal without adverse effects on nutrient digestibility, utilization of the feed and growth performance.
References
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Journal ArticleDOI

Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation

TL;DR: This review attempts to delineate common themes on the physiological and metabolic roles of cortisol in teleost fishes and to suggest new approaches that might overcome some of the inconsistencies on the role of this multifaceted hormone.
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Stress responses and disease resistance in salmonid fish: Effects of chronic elevation of plasma cortisol

TL;DR: It is shown, by means of intraperitoneal implantation of cortisol, that chronic elevation of plasma cortisol levels in the brown trout results in a dose-dependent increase in mortality due to common bacterial and fungal diseases.
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What if Minkowski had been ageusic? An alternative angle on diabetes.

TL;DR: It is suggested that the phenomena of insulin resistance and hyperglycemia might be more readily understood if viewed in the context of underlying abnormalities of lipid metabolism.
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Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)

TL;DR: It is reported here that GLP-1 confers glucose sensitivity to glucose-resistant p-cells, a phenomenon the authors term glucose competence, which is similar to membrane depolarization, the generation of action potentials, and Ca2+ influx, events that are known to trigger insulin secretion.
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Glucose-6-phosphate dehydrogenase: a "housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress.

TL;DR: The central question of this review is “How can the G6PDH gene be constitutively expressed in some tissues while displaying adaptive regulation in others when there exists a single transcription unit for the gene?”
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