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Carbohydrates in fish nutrition: effects on growth, glucose metabolism and hepatic enzymes

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TLDR
The focus then shifts to selected aspects of hormonal regulation of carbohydrate metabolism and dietary carbohydrates and their variable effects on glycogen and glucose turnover, and the correlation of dietary carbohydrates with fish health.
Abstract
The utilisation of dietary carbohydrates and their effects on fish metabolism are reviewed. Details on how dietary carbohydrates affect growth, feed utilisation and deposition of nutrients are discussed. Variations in plasma glucose concentrations emphasizing results from glucose tolerance tests, and the impact of adaptation diets are interpreted in the context of secondary carbohydrate metabolism. Our focus then shifts to selected aspects of hormonal regulation of carbohydrate metabolism and dietary carbohydrates and their variable effects on glycogen and glucose turnover. We analyse the interaction of carbohydrates with other nutrients, especially protein and protein sparing, and de novo synthesis of lipids, and finish by discussing the correlation of dietary carbohydrates with fish health.

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Journal ArticleDOI

Deep sequencing of the tilapia (Oreochromis niloticus) liver transcriptome response to dietary protein to starch ratio

TL;DR: Lower dietary protein to starch ratio resulted in markedly higher plasma cholesterol, plasma triacylglycerol, liver lipid and muscle lipid content, which indicated more fat deposition in fish.
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Glucose overload in yolk has little effect on the long-term modulation of carbohydrate metabolic genes in zebrafish (Danio rerio).

TL;DR: The use of early nutritional stimuli to program metabolic pathways in fish is ill defined as discussed by the authors, however, studies were undertaken with zebrafish to assess the effect of high glucose levels during the embryonic stage as a lifelong modulator of genes involved in carbohydrate metabolism.
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Effect of High Dietary Carbohydrate on the Growth Performance and Physiological Responses of Juvenile Wuchang Bream, Megalobrama amblycephala.

TL;DR: The results suggested that high dietary carbohydrate was detrimental to the growth performance and health of Wuchang bream.
Journal ArticleDOI

Preproinsulin expression, insulin release, and hepatic glucose metabolism after a glucose load in the omnivorous GIFT tilapia Oreochromis niloticus

TL;DR: It was concluded that glucose was an effective insulin secretagogue in tilapia, and liver played an important role to clear the glucose load through stimulation of glucose uptake, glycolysis, glycogenesis and lipogenesis.
Journal ArticleDOI

Physiological regulation of glucose transporter (GLUT4) protein content in brown trout (Salmo trutta) skeletal muscle.

TL;DR: The results show a good correlation between the changes observed in btGLUT4 protein and the previously reported changes in mRNA levels in response to alterations in circulating insulin, indicating that the regulation of bt GLUT4 in brown trout takes place predominantly in the red skeletal muscle.
References
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Journal ArticleDOI

Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation

TL;DR: This review attempts to delineate common themes on the physiological and metabolic roles of cortisol in teleost fishes and to suggest new approaches that might overcome some of the inconsistencies on the role of this multifaceted hormone.
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Stress responses and disease resistance in salmonid fish: Effects of chronic elevation of plasma cortisol

TL;DR: It is shown, by means of intraperitoneal implantation of cortisol, that chronic elevation of plasma cortisol levels in the brown trout results in a dose-dependent increase in mortality due to common bacterial and fungal diseases.
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What if Minkowski had been ageusic? An alternative angle on diabetes.

TL;DR: It is suggested that the phenomena of insulin resistance and hyperglycemia might be more readily understood if viewed in the context of underlying abnormalities of lipid metabolism.
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Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)

TL;DR: It is reported here that GLP-1 confers glucose sensitivity to glucose-resistant p-cells, a phenomenon the authors term glucose competence, which is similar to membrane depolarization, the generation of action potentials, and Ca2+ influx, events that are known to trigger insulin secretion.
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Glucose-6-phosphate dehydrogenase: a "housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress.

TL;DR: The central question of this review is “How can the G6PDH gene be constitutively expressed in some tissues while displaying adaptive regulation in others when there exists a single transcription unit for the gene?”
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