Cardiovascular Disease Resulting From a Diet and Lifestyle at Odds With Our Paleolithic Genome: How to Become a 21st-Century Hunter-Gatherer
James H. O'Keefe,Loren Cordain +1 more
Reads0
Chats0
TLDR
This review outlines the essence of the authors' hunter-gatherer genetic legacy and suggests practical steps to re-align their modern milieu with their ancient genome in an effort to improve cardiovascular health.About:
This article is published in Mayo Clinic Proceedings.The article was published on 2004-01-01 and is currently open access. It has received 298 citations till now. The article focuses on the topics: Paleolithic diet.read more
Citations
More filters
Journal ArticleDOI
Postprandial Hyperglycemia/Hyperlipidemia (Postprandial Dysmetabolism) Is a Cardiovascular Risk Factor
James H. O'Keefe,David S.H. Bell +1 more
TL;DR: The post-prandial dysmetabolism hypothesis has been bolstered by interventional studies that have demonstrated that blunting the post-andial spikes in glucose and lipids improves inflammation and endothelial function immediately as mentioned in this paper.
Journal Article
Consensus statement : Childhood obesity
Phyllis W. Speiser,Mary C J Rudolf,Henry Anhalt,Cecilia Camacho-Hübner,Francesco Chiarelli,Michael Freemark,Annette Grüters,Eli Hershkovitz,Heiko Krude,Yael Latzer,Robert H. Lustig,Ora H. Pescovitz,Orit Pinhas-Hamiel,Alan D. Rogol,Shlomit Shalitin,Charles Sultan,Pnina Vardi,George A. Werther,Zvi Zadik,Nehama Zuckerman-Levin,Zeev Hochberg,James Whitcomb +21 more
TL;DR: In developing a consensus statement, this international group has presented the evidence, developed recommendations, and provided a platform aimed toward future corrective action and ongoing debate in the international community.
Journal ArticleDOI
Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal.
TL;DR: The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals (all of whom do not develop atherosclerosis).
Journal ArticleDOI
Dietary strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health.
TL;DR: Experimental and epidemiological studies indicate that eating patterns, such as the traditional Mediterranean or Okinawan diets, that incorporate these types of foods and beverages reduce inflammation and cardiovascular risk.
Journal ArticleDOI
“Quarantine during COVID-19 outbreak: Changes in diet and physical activity increase the risk of cardiovascular disease”
TL;DR: The present commentary briefly analyzes the effects of quarantine on lifestyle, including nutrition and physical activity and the impact of new technologies in dealing with this situation, and carries some long-term effects on cardiovascular disease.
References
More filters
Journal ArticleDOI
Prevalence of the Metabolic Syndrome Among US Adults: Findings From the Third National Health and Nutrition Examination Survey
TL;DR: These results from a representative sample of US adults show that the metabolic syndrome is highly prevalent and the large numbers of US residents with the metabolic Syndrome may have important implications for the health care sector.
Journal ArticleDOI
Prevalence and Trends in Obesity Among US Adults, 1999-2000
TL;DR: The increases in the prevalences of obesity and overweight previously observed continued in 1999-2000, and increases occurred for both men and women in all age groups and for non-Hispanic whites, non- Hispanic blacks, and Mexican Americans.
Journal ArticleDOI
Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial
TL;DR: Dietary supplementation with n-3 PUFA led to a clinically important and statistically significant benefit and vitamin E had no benefit and its effects on fatal cardiovascular events require further exploration.
Journal ArticleDOI
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
TL;DR: Evidence from epidemiological studies and RCTs will be reviewed, and recommendations reflecting the current state of knowledge will be made with regard to both fish consumption and omega-3 fatty acid (plant- and marine-derived) supplementation.
Journal ArticleDOI
Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction Final Report of the Lyon Diet Heart Study
TL;DR: The protective effect of the Mediterranean dietary pattern was maintained up to 4 years after the first infarction, confirming previous intermediate analyses and indicating that a comprehensive strategy to decrease cardiovascular morbidity and mortality should include primarily a cardioprotective diet.