Journal ArticleDOI
CERR: A computational environment for radiotherapy research
TLDR
CERR provides a powerful, convenient, and common framework which allows researchers to use common patient data sets, and compare and share research results.Abstract:
A software environment is described, called the computational environment for radiotherapy research (CERR, pronounced "sir"). CERR partially addresses four broad needs in treatment planning research: (a) it provides a convenient and powerful software environment to develop and prototype treatment planning concepts, (b) it serves as a software integration environment to combine treatment planning software written in multiple languages (MATLAB, FORTRAN, C/C++, JAVA, etc.), together with treatment plan information (computed tomography scans, outlined structures, dose distributions, digital films, etc.), (c) it provides the ability to extract treatment plans from disparate planning systems using the widely available AAPM/RTOG archiving mechanism, and (d) it provides a convenient and powerful tool for sharing and reproducing treatment planning research results. The functional components currently being distributed, including source code, include: (1) an import program which converts the widely available AAPM/RTOG treatment planning format into a MATLAB cell-array data object, facilitating manipulation; (2) viewers which display axial, coronal, and sagittal computed tomography images, structure contours, digital films, and isodose lines or dose colorwash, (3) a suite of contouring tools to edit and/or create anatomical structures, (4) dose-volume and dose-surface histogram calculation and display tools, and (5) various predefined commands. CERR allows the user to retrieve any AAPM/RTOG key word information about the treatment plan archive. The code is relatively self-describing, because it relies on MATLAB structure field name definitions based on the AAPM/RTOG standard. New structure field names can be added dynamically or permanently. New components of arbitrary data type can be stored and accessed without disturbing system operation. CERR has been applied to aid research in dose-volume-outcome modeling, Monte Carlo dose calculation, and treatment planning optimization. In summary, CERR provides a powerful, convenient, and common framework which allows researchers to use common patient data sets, and compare and share research results.read more
Citations
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Journal ArticleDOI
Concomitant intensity modulated boost during whole breast hypofractionated radiotherapy--a feasibility and toxicity study.
Amy Yuen Meei Teh,Amy Yuen Meei Teh,Lorraine Walsh,Lorraine Walsh,Thomas G. Purdie,Thomas G. Purdie,Allen Mosseri,Wei Xu,Wilfred Levin,Wilfred Levin,C. Anne Koch,C. Anne Koch,Anthony Fyles,Anthony Fyles,Fei-Fei Liu,Fei-Fei Liu,B.C. John Cho,B.C. John Cho +17 more
TL;DR: CBRT using IMRT improved boost coverage and lowered OAR doses, compared with SBT, and overall treatment time was reduced.
Journal ArticleDOI
A global quality assurance system for personalized radiation therapy treatment planning for the prostate (or other sites)
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Contrasting analytical and data-driven frameworks for radiogenomic modeling of normal tissue toxicities in prostate cancer.
James Coates,Asha K. Jeyaseelan,N. Ybarra,Marc David,Sergio Faria,Luis Souhami,Fabio Cury,Marie Duclos,Issam El Naqa +8 more
TL;DR: The combination of genetic and dosimetric variables can provide significant improvement in NTCP prediction using analytical and data-driven approaches and it is shown that CNVs, in addition to SNPs, may be useful structural genetic variants in predicting radiation toxicities.
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Evaluation of target and cardiac position during visually monitored deep inspiration breath-hold for breast radiotherapy.
Leigh Conroy,R. Yeung,Elizabeth Watt,Sarah Quirk,Karen Long,Alana Hudson,Tien Phan,Wendy Smith +7 more
TL;DR: No evidence for a minimum BHL was found, suggesting that all patients who can tolerate DIBH may yield a benefit from it, andIntrabeam breath‐hold stability was found to be good, with over 96% of delivered fields within 3 mm.
Journal ArticleDOI
Dosimetric Comparison of Helical Tomotherapy and Dynamic Conformal Arc Therapy in Stereotactic Radiosurgery for Vestibular Schwannomas
Tsair-Fwu Lee,Tsair-Fwu Lee,Pei-Ju Chao,Pei-Ju Chao,Chang-Yu Wang,Chang-Yu Wang,Jen-Hong Lan,Jen-Hong Lan,Yu-Je Huang,Hsuan-Chih Hsu,Chieh-Cheng Sung,Te-Jen Su,Shi-Long Lian,Fu-Min Fang +13 more
TL;DR: The dosimetric results of stereotactic radiosurgery for vestibular schwannoma (VS) performed using dynamic conformal arc therapy (DCAT) with the Novalis system and helical TomoTherapy (HT) were compared using plan quality indices, confirming the dosimetry advantage of HT.
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Journal Article
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Paul F. Dubois,T.-Y. Yang +1 more
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