Journal ArticleDOI
CERR: A computational environment for radiotherapy research
TLDR
CERR provides a powerful, convenient, and common framework which allows researchers to use common patient data sets, and compare and share research results.Abstract:
A software environment is described, called the computational environment for radiotherapy research (CERR, pronounced "sir"). CERR partially addresses four broad needs in treatment planning research: (a) it provides a convenient and powerful software environment to develop and prototype treatment planning concepts, (b) it serves as a software integration environment to combine treatment planning software written in multiple languages (MATLAB, FORTRAN, C/C++, JAVA, etc.), together with treatment plan information (computed tomography scans, outlined structures, dose distributions, digital films, etc.), (c) it provides the ability to extract treatment plans from disparate planning systems using the widely available AAPM/RTOG archiving mechanism, and (d) it provides a convenient and powerful tool for sharing and reproducing treatment planning research results. The functional components currently being distributed, including source code, include: (1) an import program which converts the widely available AAPM/RTOG treatment planning format into a MATLAB cell-array data object, facilitating manipulation; (2) viewers which display axial, coronal, and sagittal computed tomography images, structure contours, digital films, and isodose lines or dose colorwash, (3) a suite of contouring tools to edit and/or create anatomical structures, (4) dose-volume and dose-surface histogram calculation and display tools, and (5) various predefined commands. CERR allows the user to retrieve any AAPM/RTOG key word information about the treatment plan archive. The code is relatively self-describing, because it relies on MATLAB structure field name definitions based on the AAPM/RTOG standard. New structure field names can be added dynamically or permanently. New components of arbitrary data type can be stored and accessed without disturbing system operation. CERR has been applied to aid research in dose-volume-outcome modeling, Monte Carlo dose calculation, and treatment planning optimization. In summary, CERR provides a powerful, convenient, and common framework which allows researchers to use common patient data sets, and compare and share research results.read more
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Book ChapterDOI
DIRART – A Software Suite for Deformable Image Registration and Adaptive Radiotherapy Research
Deshan Yang,Issam El Naqa,Apte Aditya,Y Wu,Murty Goddu,Sasa Mutic,Joseph O. Deasy,Daniel A. Low +7 more
TL;DR: A software suite, DIRART, for deformable image registration (DIR) plus adaptive radiotherapy (ART) research, designed in a data-oriented style with focus on usability, user-friendliness, performance, accuracy, flexibility, features, configurability and stability.
Journal ArticleDOI
Mesorectal radiotherapy for early stage rectal cancer: A novel target volume
Femke P. Peters,Mark Teo,Ane L Appelt,Simon P. Bach,Gunnar Baatrup,Johannes H. W. de Wilt,C. Kronborg,Karen-Lise Garm Spindler,Corrie A.M. Marijnen,David Sebag-Montefiore +9 more
TL;DR: The rationale behind the novel, mesorectal only radiotherapy treatment used in the STAR-TREC trial specifically tailored for early stage disease, with the goal of organ preservation is described.
Journal ArticleDOI
A preliminary study of in-house Monte Carlo simulations: an integrated Monte Carlo verification system.
Nobutaka Mukumoto,K. Tsujii,S. Saito,Masayoshi Yasunaga,Hideki Takegawa,Tokihiro Yamamoto,Hodaka Numasaki,Teruki Teshima +7 more
TL;DR: Development of the MCVS was successful for performing MC simulations and analyzing dose distributions and calculation time was improved in line with the increase in the number of central processing units (CPUs) at a computation efficiency of more than 98%.
Journal ArticleDOI
CTC-ask: a new algorithm for conversion of CT numbers to tissue parameters for Monte Carlo dose calculations applying DICOM RS knowledge
TL;DR: A novel algorithm, CTC-ask, which enables locally confined constraints for the media assignment and is independent of the number of media used for the conversion of CT number to density, and is able to reduce anatomically irrational media assignment.
Journal ArticleDOI
Integration of Diffusion Magnetic Resonance Tractography into tomotherapy radiation treatment planning for high-grade gliomas
Luisa Altabella,Sara Broggi,Paola Mangili,Gian Marco Conte,Valentina Pieri,Antonella Iadanza,Antonella del Vecchio,Nicoletta Anzalone,Nadia Di Muzio,Riccardo Calandrino,Andrea Falini,Antonella Castellano +11 more
TL;DR: The integration of MR Tractography into radiotherapy planning is feasible and beneficial to preserve important WM structures without reducing the clinical goal of radiation treatment.
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Extending Python with Fortran
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Journal Article
Extending python with Fortran
Paul F. Dubois,T.-Y. Yang +1 more
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