Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective
Sarah Finocchario-Kessler,Catherine Wexler,May Maloba,Natabhona Mabachi,Florence Ndikum-Moffor,Elizabeth A. Bukusi,Elizabeth A. Bukusi +6 more
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TLDR
Cervical cancer research in African countries has increased steadily over the past decade, but more is needed as quality of life of cervical cancer survivors and secondary prevention are two severely under-researched areas.Abstract:
Women living in Africa experience the highest burden of cervical cancer. Research and investment to improve vaccination, screening, and treatment efforts are critically needed. We systematically reviewed and characterized recent research within a broader public health framework to organize and assess the range of cervical cancer research in Africa. We searched online databases and the Internet for published articles and cervical cancer reports in African countries. Inclusion criteria included publication between 2004 and 2014, cervical cancer-related content pertinent to one of the four public health categories (primary, secondary, tertiary prevention or quality of life), and conducted in or specifically relevant to countries or regions within the African continent. The study design, geographic region/country, focus of research, and key findings were documented for each eligible article and summarized to illustrate the weight and research coverage in each area. Publications with more than one focus (e.g. secondary and tertiary prevention) were categorized by the primary emphasis of the paper. Research specific to HIV-infected women or focused on feasibility issues was delineated within each of the four public health categories. A total of 380 research articles/reports were included. The majority (54.6 %) of cervical cancer research in Africa focused on secondary prevention (i.e., screening). The number of publication focusing on primary prevention (23.4 %), particularly HPV vaccination, increased significantly in the past decade. Research regarding the treatment of precancerous lesions and invasive cervical cancer is emerging (17.6 %), but infrastructure and feasibility challenges in many countries have impeded efforts to provide and evaluate treatment. Studies assessing aspects of quality of life among women living with cervical cancer are severely limited (4.1 %). Across all categories, 11.3 % of publications focused on cervical cancer among HIV-infected women, while 17.1 % focused on aspects of feasibility for cervical cancer control efforts. Cervical cancer research in African countries has increased steadily over the past decade, but more is needed. Tertiary prevention (i.e. treatment of disease with effective medicine) and quality of life of cervical cancer survivors are two severely under-researched areas. Similarly, there are several countries in Africa with little to no research ever conducted on cervical cancer.read more
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Prevention of Cervical Cancer in Sub-Saharan Africa: The Advantages and Challenges of HPV Vaccination.
Eleanor Black,Robyn Richmond +1 more
TL;DR: Rwanda’s experience of achieving high vaccination coverage in their national HPV immunization program is used as a case study to explore effective approaches to the design and implementation of HPV vaccination programs in SSA.
Awareness of Cervical Cancer, Papanicolaou's Smearand Its Utilisation among Female Undergraduates inIbadan
TL;DR: A survey was conducted among 421 undergraduates of the University of Ibadan probing into their risk factors for neoplastic cervical lesions, awareness of cervical cancer, Papanicolaou's smear and its utilisation, finding awareness was found to be more among medical students and the married ones.
An Ethnographic Study of Cervical Cancer Among Women in Rural Kenya
J. W Gatune,Isaac K. Nyamongo +1 more
TL;DR: This article assesses knowledge, attitudes, and practices regarding cervical cancer among rural women of Kenya and proposes a folk causal model to explain the link between these factors and cervical cancer.
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Barriers and facilitators to uptake of cervical cancer screening among women in Uganda: a systematic review
TL;DR: Understanding the barriers and facilitators to cervical cancer screening encountered by Ugandan women can guide efforts to increase screening rates in this population and inspire efforts to remove barriers and enhance facilitators.
Journal ArticleDOI
Predictors of cervical cancer screening among Kenyan women: results of a nested case-control study in a nationally representative survey
Anne Ng’ang’a,Mary Nyangasi,Nancy G Nkonge,Eunice Gathitu,Joseph Kibachio,Peter Gichangi,Richard G. Wamai,Catherine Kyobutungi +7 more
TL;DR: Strategies to improve cervical cancer screening in Kenya should be implemented with messages targeting persons with both risky and non-risky lifestyles especially younger women with no formal education living in rural areas.
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