Charge density-dependent strength of hydration and biological structure
TLDR
The standard heat of solution of a crystalline alkali halide is shown here to be negative (exothermic) only when one ion is a kosmotrope and the ion of opposite charge is a chaotrope, which suggests that inner sphere ion pairs are preferentially formed between oppositely charged ions with matching absolute enthalpies of hydration.About:
This article is published in Biophysical Journal.The article was published on 1997-01-01 and is currently open access. It has received 1122 citations till now. The article focuses on the topics: Kosmotropic & Ion.read more
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Sodium/Calcium Exchange: Its Physiological Implications
TL;DR: In cardiac myocytes, and probably other cell types, the exchanger serves a housekeeping role by maintaining a low intracellular Ca2+ concentration; its possible role in cardiac excitation-contraction coupling is controversial.
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Biocatalysis in ionic liquids
TL;DR: Roger Sheldon developed the concepts of E factors and atom utilization for assessing the environmental impact of chemical processes, particularly in relation to fine chemicals production.
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Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 Å Resolution
TL;DR: A single-base-pair increase in DNA length over that used previously results in substantially improved clarity of the electron density and accuracy for the histone protein and DNA atomic coordinates, and reduced disorder has allowed for the first time extensive modeling of water molecules and ions.
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Stability of Protein Pharmaceuticals: An Update
TL;DR: This review summarizes the advances that have been made since then regarding protein stabilization and formulation and discusses the current understanding of chemical and physical instability.
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Ions from the Hofmeister series and osmolytes: effects on proteins in solution and in the crystallization process.
TL;DR: The surface potential difference and surface tension at an air-salt solution interface are used to generate a simple model for how ions affect protein stability and solubility through indirect interactions at the protein-solution interface.
References
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Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.
TL;DR: In this article, the rat pancreas RNA was used as a source for the purification of alpha-amylase messenger ribonucleic acid (RBA) using 2-mercaptoethanol.
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Intermolecular and surface forces
TL;DR: The forces between atoms and molecules are discussed in detail in this article, including the van der Waals forces between surfaces, and the forces between particles and surfaces, as well as their interactions with other forces.
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The Hofmeister effect and the behaviour of water at interfaces.
TL;DR: The first general, detailed qualitative molecular mechanism for the origins of ion-specific (Hofmeister) effects on the surface potential difference at an air-water interface is proposed; this mechanism suggests a simple model for the behaviour of water at all interfaces, regardless of whether the non-aqueous component is neutral or charged, polar or non-polar.
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A Method for Isolation of Intact, Translationally Active Ribonucleic Acid
Guy Cathala,Jean-François Savouret,Bernardita Mendez,Brian L. West,Michael Karin,Joseph Martial,John D. Baxter +6 more
TL;DR: A method for isolation of large, translationally active RNA species is presented and yields large mRNA precursors up to 10 kb and mRNA species which translate very well, however, small RNA species are recovered with a poor yield.