Journal ArticleDOI
Chiral Bronsted acid catalyzed Friedel-Crafts alkylation reactions
Shu-Li You,Quan Cai,Mi Zeng +2 more
TLDR
In this tutorial review, recent progress in the development of chiral Brønsted acid-catalyzed asymmetric Friedel-Crafts reactions is presented.Abstract:
The asymmetric Friedel–Crafts reaction is one of the most powerful methods to synthesize optically active aromatic compounds. Particularly, the Friedel–Crafts alkylation of arenes with unsaturated compounds activated by chiral Bronsted acids provides direct access to enantiopure aromatic derivatives with perfect atom economy. In this tutorial review, recent progress in the development of chiral Bronsted acid-catalyzed asymmetric Friedel–Crafts reactions is presented.read more
Citations
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Beyond directing groups: transition-metal-catalyzed C-H activation of simple arenes.
TL;DR: In this review, recent advances in the emerging field of non-chelate-assisted C-H activation are discussed, highlighting some of the most intriguing and inspiring examples of induction of reactivity and selectivity.
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Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
Journal ArticleDOI
Combining transition metal catalysis and organocatalysis--an update.
TL;DR: Recent remarkable progress in the field of combined transition metal catalysis and organocatalysis is summarized, further highlighting the potential of this new and exciting research area and the many challenges that still remain for the future.
Journal ArticleDOI
Recent Developments in Asymmetric Organocatalytic Domino Reactions
TL;DR: The field of asymmetric organocatalytic biomolecular cascades has become one of the most fascinating and current fields in organic chemistry as discussed by the authors, and the literature has been rapidly developing.
Journal ArticleDOI
Chiral Brønsted acids in enantioselective carbonyl activations – activation modes and applications
TL;DR: Different activation modes, key features of the catalysts and the applied substrates are presented and discussed with the goal to elucidate the origin of stereoselectivity in these Brønsted acid catalyzed transformations.
References
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Journal ArticleDOI
Small-molecule H-bond donors in asymmetric catalysis.
Journal ArticleDOI
Asymmetric catalysis by chiral hydrogen-bond donors.
Mark S. Taylor,Eric N. Jacobsen +1 more
TL;DR: This review documents the structural and mechanistic features that contribute to high enantioselectivity in hydrogen-bond-mediated catalytic processes in small-molecule, synthetic catalyst systems.
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Catalytic asymmetric Friedel-Crafts alkylation reactions--copper showed the way.
TL;DR: Alkylation with Activated Alkenes and Carbonyl Compounds in Copper Complexes and Other Metal Complexes: The Incubation Period 2904-2904 3.2.1.
Journal ArticleDOI
Hydrogen-bond-mediated asymmetric catalysis.
Xinhong Yu,Wei Wang,Wei Wang +2 more
TL;DR: The examples provided neatly demonstrate that chiral ureas and thioureas, diols, and phosphoric acids display effective and unique activation modes of catalysis for a broad spectrum of asymmetric organic transformations, including single-step and multiple-step cascade reactions.