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Chronic arsenic poisoning: a global health issue -- a report of multiple primary cancers.

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TLDR
A case presenting with multiple cutaneous cancers as well as an internal lung primary in a patient exposed to toxic levels of As in the drinking water is discussed along with a review of literature.
Abstract
Chronic arsenic (As) poisoning is a worldwide public health problem. Effects of prolonged exposure to high levels of As in drinking water have been observed and documented in various epidemiological studies from all over the world. The non-malignant cutaneous effects of chronic exposure to inorganic As are well known. A case presenting with multiple cutaneous cancers as well as an internal lung primary in a patient exposed to toxic levels of As in the drinking water is discussed along with a review of literature.

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Association of Arsenic with Adverse Pregnancy Outcomes/Infant Mortality: A Systematic Review and Meta-Analysis

TL;DR: In this paper, the authors conducted a study on the effects of exposure to arsenic on human reproduction and found that arsenic exposure is one of the major global health problems, affecting > 300 million people worldwide.
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Arsenic Removal from Vietnamese Groundwater Using the Arsenic-Binding DNA Aptamer

TL;DR: Single-stranded DNA aptamers generated from a random library to remove arsenic from Vietnamese groundwater revealed the Ars-3 aptamer to have the highest affinity to arsenate and arsenite with a dissociation constant of 4.95 +/-0.31 and 7.05 +/- 0.91 nM, respectively.
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A novel biosensor based on Au@Ag core-shell nanoparticles for SERS detection of arsenic (III).

TL;DR: This work proposes for the first time a simple and novel approach based on SERS and As (III) -aptamer for detection of As ( III) with excellent selectivity and sensitivity and was demonstrated in monitoring As (II) in lake water samples with satisfactory results.
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Arsenic–glutathione conjugate transport by the human multidrug resistance proteins (MRPs/ABCCs)

TL;DR: The ATP-binding cassette (ABC) transporter proteins, multidrug resistance protein 1 (MRP1/ABCC1 and the related protein MRP2 (ABCC2), are thought to play an important role in arsenic detoxification through the cellular efflux of arsenic-GSH conjugates.
References
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Groundwater Arsenic Contamination inBangladesh andWestBengal, India

TL;DR: In this paper, the authors have collected 10,991 water smples from 42 arsenic-affected districts in Bangladesh for analysis, 58,166 water samples from nine arsenic affected districts inWestBengal.
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Chronic health effects in people exposed to arsenic via the drinking water: dose–response relationships in review

TL;DR: Prospective studies in large area of endemic As poisoning, like Bangladesh or China, where the rate of malignancies is expected to increase within the next several decades, will help to clarify the dose-response relationship between As exposure levels and adverse health effects with enhanced accuracy.
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Arsenic poisoning in the Ganges delta

TL;DR: Observations indicate that arsenic- rich pyrite and other arsenic minerals, which were proposed in previous models to give rise to arsenic pollution, are rare or even absent in the sediments of the Ganges delta.
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Ingested Arsenic and Internal Cancer: A Historical Cohort Study Followed for 33 Years

TL;DR: The analysis according to the skin signs of chronic arsenicism in 1959 showed that they were useful risk indicators for subsequent cancer development in the development of lung cancer, and there was evidence of synergism between arsenic intake and smoking habit.
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Pathology related to chronic arsenic exposure.

TL;DR: An overview of arsenic-induced pathology is provided, case reports that relate to arsenical medications for such conditions as asthma, psoriasis, and syphilis are presented, and five case reports from the ITTRCA are presented.
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