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Classification and psychopathology research.

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TLDR
It is pointed out that a wide variety of etiological factors have been implicated in the etiology of psychopathology, and that there is no empirical or conceptual reason to privilege any particular level of explanation.
Abstract
The classification of psychopathology appears to be at a crossroads, with a new version of the Diagnostic and Statistical Manual of Mental Disorders impending and one of the current aspirations of the National Institute of Mental Health being the development of new ways of classifying mental disorders. This article discusses what we currently know about psychopathology and the role that classification has played in psychopathology research. It is pointed out that a wide variety of etiological factors, both within and outside the individual, have been implicated in the etiology of psychopathology, and that there is no empirical or conceptual reason to privilege any particular level of explanation. The ways in which signs/symptoms and disorders may be related are discussed, including their implications for classification. The value of theory development and theory-driven research is emphasized, along with the potential perils of generating an ossified classification scheme that must be adhered to.

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Citations
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The NIMH Research Domain Criteria Initiative: Background, Issues, and Pragmatics.

TL;DR: A number of theoretical and methodological issues that can arise in connection with the nature of RDoC constructs are highlighted: subjectivism and heterophenomenology, desynchrony and theoretical neutrality among units of analysis, theoretical reductionism, endophenotypes, biomarkers, neural circuits, construct "grain size," and analytic challenges.
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Transdiagnostic approaches to mental health problems: Current status and future directions.

TL;DR: This Introduction to a Special Section on Transdiagnostic Approaches to Psychopathology provides a narrative review of the transdiagnostic literature and outlines several challenges it currently faces that arguably limit its applicability in current mental health science and practice.
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Clashing Diagnostic Approaches: DSM-ICD Versus RDoC

TL;DR: RDoC appears to be a valuable endeavor that holds out the long-term promise of an alternative system of mental illness classification, and three sets of pressing challenges--conceptual, methodological, and logistical/pragmatic--that must be addressed for RDoC to realize its scientific potential are outlined.
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The Research Domain Criteria (RDoC): an analysis of methodological and conceptual challenges.

TL;DR: The RDoC endeavor faces several methodological and conceptual challenges, four of which are addressed here: an overemphasis on biological units and measures, neglect of measurement error, biological and psychometric limitations of endophenotypes, and the distinction between biological predispositions and their behavioral manifestations.
References
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Journal ArticleDOI

Construct validity in psychological tests.

TL;DR: The present interpretation of construct validity is not "official" and deals with some areas where the Committee would probably not be unanimous, but the present writers are solely responsible for this attempt to explain the concept and elaborate its implications.
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Hopelessness depression: A theory-based subtype of depression.

TL;DR: The hopelessness theory is silent about the time lag between formation of hopelessness and onset of the symptoms of depression as mentioned in this paper, however, the hopelessness cause, as opposed to a hopelessness subtype, of depression has not been examined.
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Schizotaxia, Schizotypy, Schizophrenia

TL;DR: While I have not until recently begun any systematic research efforts on this baffling disorder, I felt that to share with you some of my thoughts, based though they are upon clinical impressions in the context of selected research by others, might be an acceptable use of this occasion.
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The Structure of Genetic and Environmental Risk Factors for Common Psychiatric and Substance Use Disorders in Men and Women

TL;DR: The underlying structure of the genetic and environmental risk factors for the common psychiatric and drug abuse disorders in men and women is very similar.
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