Journal ArticleDOI
Clinical and pathological features of primary neuroectodermal tumor/Ewing sarcoma of the kidney.
Emanuela Risi,Roberto Iacovelli,Amelia Altavilla,Daniele Alesini,Antonella Palazzo,Claudia Mosillo,Patrizia Trenta,Enrico Cortesi +7 more
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TLDR
The findings suggest that PNET/EWS is a rare aggressive tumor affecting principally young people, with a poor prognosis for patients with M1 disease; chemotherapy is an effective strategy in M1 Disease and probably also in M0 disease.About:
This article is published in Urology.The article was published on 2013-08-01. It has received 55 citations till now. The article focuses on the topics: Primitive neuroectodermal tumor & Neuroectodermal tumor.read more
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Journal ArticleDOI
Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Kidney: A Rare and Lethal Entity.
Romulo Celli,Guoping Cai +1 more
TL;DR: Important considerations with regards to morphology, immunohistochemistry, and molecular alterations will be reviewed here and should be taken into account before rendering this rare and lethal diagnosis.
Journal ArticleDOI
Ewing sarcoma of the kidney: a rare entity.
Maria Fernanda Arruda Almeida,Madhavi Patnana,Brinda Rao Korivi,Neda Kalhor,Leonardo P. Marcal +4 more
TL;DR: Ewing sarcoma and primitive peripheral neuroectodermal tumor (PNET) are high-grade malignant tumors typically found in children and adolescents and the prognosis of those with metastatic disease is poor.
Journal ArticleDOI
Ewing Sarcoma With Emphasis on Extra-skeletal Ewing Sarcoma: A Decade's Experience From a Single Centre in India.
Sudha S Murthy,Sundaram Challa,Kvvn Raju,Senthil Rajappa,Daphne Fonseca,Sandhya Devi Gundimeda,B V Rao,Faiq Ahmed,Suseela Kodandapani,Lavanya Nambaru,Manasi C. Mundada,Rakesh Sharma,Krishna Mohan Mallavarapu,Veeraiah Koppula,T. S. Rao +14 more
TL;DR: Molecular tests were performed more frequently in extra-skeletal tumours, especially in visceral tumours to establish the diagnosis of Ewing sarcoma family of tumours with emphasis on sex, age, and location.
Journal ArticleDOI
Ewing’s sarcoma/primitive neuroectodermal tumor of the kidney: a case report and literature review
TL;DR: An 18-year-old man diagnosed with renal ES/PNET, who suffered from a sudden left flank pain associated with gross hematuria, is reported, who underwent laparoscopic nephrectomy of the left kidney.
Journal ArticleDOI
Primary Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Kidney: The MD Anderson Cancer Center Experience.
Nidale Tarek,Rabih Said,Clark R. Andersen,Tina Suki,Jessica Foglesong,Jessica Foglesong,Cynthia E. Herzog,Nizar M. Tannir,Shreyaskumar Patel,Ravin Ratan,Joseph A. Ludwig,Najat C. Daw +11 more
TL;DR: It was found that the 4-year overall survival for patients without metastasis was 85% compared to 47% for patients with metastasis and local tumor extension beyond the kidney, tumor thrombus, and distant metastasis are unfavorable factors that warrant intensification or novel approaches of therapy.
References
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Journal ArticleDOI
Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.
Holcombe E. Grier,Mark Krailo,Nancy J. Tarbell,Michael P. Link,Chris Fryer,Douglas J. Pritchard,Mark C. Gebhardt,Paul S. Dickman,Elizabeth J. Perlman,Paul A. Meyers,Sarah S. Donaldson,Sheila Moore,Aaron R. Rausen,Teresa J. Vietti,James S. Miser +14 more
TL;DR: The addition of ifosfamide and etoposide to a standard regimen does not affect the outcome for patients with metastatic disease, but it significantly improves the outcomeFor patients with nonmetastatic Ewing's Sarcoma, primitive neuroectodermal tumor of bone, or primitive sarcoma of bone.
Book
Histology for Pathologists
TL;DR: Bone marrow, S.N.Wickramasinghe adipose tissue, John J. Brooks and Patricia M.Roth skeletal muscle, R Reid Heffner Jr myofibroblast, Walte Schurch et al central nervous system, Gregory N. Fuller and Peter C. Burger peripheral nervous system.
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EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma.
E de Alava,Akira Kawai,John H. Healey,I. Fligman,P. A. Meyers,Andrew G. Huvos,William L. Gerald,Suresh C. Jhanwar,Pedram Argani,C. R. Antonescu,F J Pardo-Mindán,Jill P. Ginsberg,Richard B. Womer,Elizabeth R. Lawlor,Jay S. Wunder,Irene L. Andrulis,Poul H. Sorensen,Frederic G. Barr,Marc Ladanyi +18 more
TL;DR: EWS-FLI1 fusion type appears to be prognostically relevant in ES, independent of tumor site, stage, and size.
Journal ArticleDOI
Ewing’s Sarcoma Family of Tumors: Current Management
Mark L. Bernstein,Heinrich Kovar,Michael Paulussen,R. L. Randall,Andreas Schuck,Lisa A. Teot,Herbert Juergens +6 more
TL;DR: Patients with initially metastatic disease fare less well, with about one quarter surviving, and new approaches include anti-angiogenic therapy, particularly since vascular endothelial growth factor is an apparent downstream target of the ews-fli1 oncogene.
Journal ArticleDOI
Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: A clinicopathologic and immunohistochemical analysis of 11 cases
Rafael E. Jimenez,Andrew L. Folpe,Rosanna L. Lapham,Jae Y. Ro,Patricia A. O'shea,Sharon W. Weiss,Mahul B. Amin,Mahul B. Amin +7 more
TL;DR: A unique proclivity of renal ES/PNET for young adults is affirms and that it is a highly aggressive neoplasm, with rapid death in many cases, usually after the development of treatment-resistant lung metastases.