Journal ArticleDOI
Clinical Applications of Allograft Skin in Burn Care.
TLDR
The up-to-date clinical application of allograft in burn care was reviewed, including coverage of extensive burn wounds, combined use with meshed autograft, template for delayed application of cultured epidermal autografteds, and the use of human acellular dermal matrix.Abstract:
Allograft skin has been widely used for wound management in burn centers. Functional as biologic dressing, it can not only provide ideal temporary wound coverage in extensive burns when autograft is not immediately available but also prepare the wound bed for definitive autografting. In this article, the up-to-date clinical application of allograft in burn care was reviewed, including coverage of extensive burn wounds, combined use with meshed autograft, template for delayed application of cultured epidermal autografts, and the use of human acellular dermal matrix. Although it has potential disadvantages of rejection and disease transmission, allograft skin remains a workhorse in treatment of severe burn wounds.read more
Citations
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Journal ArticleDOI
Cultured Epithelium as a Skin Substitute
TL;DR: The history of techniques for the replacement of lost skin is reviewed, including the current research in the use of synthetic dermal substitutes, skin allografts and immunosuppression, and tissue-cultured epithelial autografteds.
Journal ArticleDOI
Historical Evolution of Skin Grafting-A Journey through Time.
Michael Kohlhauser,Hanna Luze,Hanna Luze,Sebastian P. Nischwitz,Sebastian P. Nischwitz,Lars-Peter Kamolz,Lars-Peter Kamolz +6 more
TL;DR: In this paper, the authors give an overview about the evolution of skin grafting and its usage in burn care nowadays, and present an overview of the most popular techniques used in burn wound coverage.
Journal ArticleDOI
A Short History of Skin Grafting in Burns: From the Gold Standard of Autologous Skin Grafting to the Possibilities of Allogeneic Skin Grafting with Immunomodulatory Approaches
TL;DR: The achievements in burn surgery with regards to skin allotransplantation in recent years are reviewed in this paper, where the achievement of various milestones over the past decades has provided thought-provoking impulses in the field of skin allografting and transplant immunology.
Journal ArticleDOI
Facile fabrication of soy protein isolate-functionalized nanofibers with enhanced biocompatibility and hemostatic effect on full-thickness skin injury.
Meifang Ke,Zijian Wang,Qi Dong,Feixiang Chen,Liu He,Céline Huselstein,Xinghuan Wang,Yun Chen +7 more
TL;DR: In this paper, a series of biocompatible and hemostatic nanofiber dressings were fabricated for high-voltage electrospinning, and the obtained products were coded as SPNF-n (n = 100, 80, 60 and 40), corresponding to the weight percentage of poly(L-lactic acid) solution.
References
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Journal ArticleDOI
Grafting of burns with cultured epithelium prepared from autologous epidermal cells
TL;DR: The cells from a small piece of epidermis can be grown into a large number of cultured epithelia, which were grafted onto full-thickness burn wounds in two patients, and survived for the period of observation.
Journal ArticleDOI
Clinical Evaluation of an Acellular Allograft Dermal Matrix in Full-Thickness Burns
David J. Wainwright,Michael R. Madden,Arnold Luterman,John F. Hunt,William W. Monafo,David M. Heimbach,Richard J. Kagan,Kevin Sittig,Alan R. Dimick,David N. Herndon +9 more
TL;DR: Wound assessment over time showed that thin split-thickness autografts plus allograft dermal matrix were equivalent to thicker split- Thirteen-day take rates of the dermal Matrix were statistically equivalent to the control autografteds.
Journal ArticleDOI
Use of cultured epidermal autografts and dermal allografts as skin replacement after burn injury.
TL;DR: An adult with burns over 55% of body surface area was treated with cadaver skin allografts and complete reconstitution of skin, consisting of epidermal autograft and dermalAllograft, was achieved.
Journal ArticleDOI
Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state
M. De Luca,Enrico Albanese,Sergio Bondanza,M. Megna,L. Ugozzoli,F. Molina,Ranieri Cancedda,P.L. Santi,M. Bormioli,M. Stella,G. Magliacani +10 more
TL;DR: Clinical results obtained from a multicentre experience of the use of autologous and allogenic cultured human epidermal cells in the treatment of partial and full skin thickness burns are described.