Clustering Algorithms: Their Application to Gene Expression Data
Jelili Oyelade,Itunuoluwa Isewon,Funke Oladipupo,Olufemi Aromolaran,Efosa Uwoghiren,Faridah Ameh,Moses Achas,Ezekiel Adebiyi +7 more
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TLDR
This review examines the various clustering algorithms applicable to the gene expression data in order to discover and provide useful knowledge of the appropriate clustering technique that will guarantee stability and high degree of accuracy in its analysis procedure.Abstract:
Gene expression data hide vital information required to understand the biological process that takes place in a particular organism in relation to its environment. Deciphering the hidden patterns in gene expression data proffers a prodigious preference to strengthen the understanding of functional genomics. The complexity of biological networks and the volume of genes present increase the challenges of comprehending and interpretation of the resulting mass of data, which consists of millions of measurements; these data also inhibit vagueness, imprecision, and noise. Therefore, the use of clustering techniques is a first step toward addressing these challenges, which is essential in the data mining process to reveal natural structures and identify interesting patterns in the underlying data. The clustering of gene expression data has been proven to be useful in making known the natural structure inherent in gene expression data, understanding gene functions, cellular processes, and subtypes of cells, mining useful information from noisy data, and understanding gene regulation. The other benefit of clustering gene expression data is the identification of homology, which is very important in vaccine design. This review examines the various clustering algorithms applicable to the gene expression data in order to discover and provide useful knowledge of the appropriate clustering technique that will guarantee stability and high degree of accuracy in its analysis procedure.read more
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Book ChapterDOI
A Short Review on Different Clustering Techniques and Their Applications
TL;DR: A concise description of the existing types of clustering approaches is given followed by a survey of the fields where clustering analytics has been effectively employed in pattern recognition and knowledge discovery.
Proceedings ArticleDOI
Data Clustering: Algorithms and Its Applications
Jelili Oyelade,Itunuoluwa Isewon,O. O. Oladipupo,Onyeka Emebo,Zacchaeus O. Omogbadegun,Olufemi Aromolaran,Efosa Uwoghiren,Damilare Olaniyan,Obembe O. Olawole +8 more
TL;DR: Application of data clustering was systematically discussed in view of the characteristics of the different clustering techniques that make them better suited or biased when applied to several types of data, such as uncertain data, multimedia data, graph data, biological data, stream data, text data, time series data, categorical data and big data.
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