Journal ArticleDOI
Comparison by meta-analysis of mortality after isolated coronary artery bypass grafting in women versus men.
Mahboob Alam,Salman Bandeali,Waleed T. Kayani,Waqas Ahmad,Saima A. Shahzad,Hani Jneid,Hani Jneid,Yochai Birnbaum,Neal S. Kleiman,Neal S. Kleiman,Joseph S. Coselli,Christie M. Ballantyne,Nasser Lakkis,Salim S. Virani +13 more
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TLDR
Mortality remained independently associated with female gender despite propensity score-matched analysis of outcomes, and women who underwent isolated CABG experienced higher mortality at short-term, midterm, and long-term follow-up compared with men.Abstract:
Short- and long-term mortality in women who undergo coronary artery bypass grafting (CABG) has been evaluated in multiple studies with conflicting results. The investigators conducted a meta-analysis of all existing studies to evaluate the impact of female gender on mortality in patients who undergo isolated CABG. A comprehensive search of studies published through May 31, 2012 identified 20 studies comparing men and women who underwent isolated CABG. All-cause mortality was evaluated at short-term (postoperative period and/or at 30 days), midterm (1-year), and long-term (5-year) follow-up. Odds ratios (ORs) and 95% confidence interval (CIs) were calculated using a random-effects model. A total of 966,492 patients (688,709 men [71%], 277,783 women [29%]) were included in this meta-analysis. Women were more likely to be older; had significantly greater co-morbidities, including hypertension, diabetes mellitus, hyperlipidemia, unstable angina, congestive heart failure, and peripheral vascular disease; and were more likely to undergo urgent CABG (51% vs 44%, pread more
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Journal ArticleDOI
Sex Differences in Long-Term Survival After Major Cardiac Surgery: A Population-Based Cohort Study.
TL;DR: Female sex was associated with long‐term mortality after cardiac surgery and perioperative optimization and long-term follow‐up should be tailored to younger women with a history of myocardial infarction and percutaneous coronary intervention and older men with ahistory of chronic obstructive pulmonary disease and depression.
Journal ArticleDOI
Gender differences in patients undergoing surgery for acute type A aortic dissection
TL;DR: There are no differences in early and long-term outcomes between male and female patients undergoing surgery for acute type A aortic dissection and female gender was not an independent predictor of operative and late mortality.
Journal ArticleDOI
Gender differences in outcomes following isolated coronary artery bypass grafting: long-term results.
Francesco Nicolini,Antonella Vezzani,Daniela Fortuna,Giovanni Andrea Contini,Davide Pacini,Davide Gabbieri,Claudio Zussa,Rossana De Palma,Tiziano Gherli +8 more
TL;DR: Women are more likely to be readmitted with myocardial infarction and congestive heart failure after CABG but experience survival similar to that observed in men, while female gender was not an independent risk factor for mortality.
Journal ArticleDOI
An Update on Gender Disparities in Coronary Heart Disease Care
TL;DR: This review provides updates in gender disparities in the management of risk factors, treatments, and outcomes of coronary heart disease.
Journal ArticleDOI
Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data.
Mario Gaudino,Antonino Di Franco,John H. Alexander,Faisal G. Bakaeen,Natalia N. Egorova,Paul Kurlansky,Andreas Boening,Joanna Chikwe,Michelle Demetres,Philip J. Devereaux,Anno Diegeler,Arnaldo Dimagli,Marcus Flather,Irbaz Hameed,Andre Lamy,Jennifer S. Lawton,Wilko Reents,N. Bryce Robinson,Katia Audisio,Mohamed Rahouma,Patrick W. Serruys,Hironori Hara,David P. Taggart,Leonard N. Girardi,Stephen E. Fremes,Umberto Benedetto +25 more
TL;DR: In this article, a systematic review and pooled analysis of high-quality individual patient data from large CABG trials to compare the adjusted outcomes of women and men was conducted, showing that women have worse outcomes than men after coronary artery bypass grafting.
References
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TL;DR: The Newcastle-Ottawa Scale (NOS) as discussed by the authors was developed to assess the quality of nonrandomised studies with its design, content and ease of use directed to the task of incorporating the quality assessments in the interpretation of meta-analytic results.
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Increased Mortality of Women in Coronary Artery Bypass Surgery: Evidence for Referral Bias
TL;DR: Women are referred for coronary bypass surgery later in the course of their disease than men, and later referral may increase their changes of operative death.
Journal ArticleDOI
Association of sex, physical size, and operative mortality after coronary artery bypass in the Coronary Artery Surgery Study (CASS).
Lloyd D. Fisher,J W Kennedy,Kathryn B. Davis,Charles Maynard,J K Fritz,George C. Kaiser,William O. Myers +6 more
TL;DR: The physical size of the patient, including coronary artery diameter, helps predict operative mortality even after adjusting for differences in risk predicted by the basic variables and gender, and the patient's sex is not statistically significantly related to the risk of surgical death given the information available from clinical and angiographic variables.
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Impact of Gender on Coronary Bypass Operative Mortality
TL;DR: Gender is an independent predictor of operative mortality except for patients in very high- risk categories, but in high-risk patients, there was no difference between male and female mortality.