Journal ArticleDOI
Comparison of effects of LLLT and LIPUS on fracture healing in animal models and patients: A systematic review
TLDR
It is suggested that both LIP US and LLLT may be beneficial to fracture healing in patients, and that LIPUS is more effective.Abstract:
The aim of this paper is to study the in vivo potency of low-level laser therapy (LLLT) and low intensity pulsed ultrasound (LIPUS) alone, accompanied by bone grafts, or accompanied by other factors on fracture healing in animal models and patients. In this paper, we aim to systematically review the published scientific literature regarding the use of LLLT and LIPUS to accelerate fracture healing in animal models and patients. We searched the PubMed database for the terms LLLT or LIPUS and/or bone, and fracture. Our analysis also suggests that both LIPUS and LLLT may be beneficial to fracture healing in patients, and that LIPUS is more effective. These finding are of considerable importance in those treatments with a LIPUS, as a laser device may reduce healing time. The most clinically relevant impact of the LIPUS treatment could be a significant reduction in the proportion of patients who go on to develop a nonunion. If it is confirmed that the therapeutic influence is true and reliable, patients will obtain benefits from LIPUS and LLLT. Further clinical trials of high methodological quality are needed in order to determine the optimal role of LIPUS and LLLT in fracture healing in patients.read more
Citations
More filters
Proceedings Article
Effects of low laser irradiation on angiogenesis in injured rat tibiae
TL;DR: The influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied to identify molecular mechanisms involved in low-level laser therapy of angiogenesis in post-traumatic bone regeneration.
The Role of Low Intensity Pulsed Ultrasound Therapy in the Management of Acute Fractures : A Systematic Review
TL;DR: The literature supports the use of LIPUS in the treatment of acute fractures treated with plaster immobilization, and seven randomized controlled trials and two meta-analyses were retrieved using the search strategy.
Journal ArticleDOI
Fibrin Sealant Derived from Human Plasma as a Scaffold for Bone Grafts Associated with Photobiomodulation Therapy.
Karina Torres Pomini,Daniela Vieira Buchaim,Jesus Carlos Andreo,Marcelie Priscila de Oliveira Rosso,Bruna Botteon Della Coletta,Iris Jasmin Santos German,Ana Carolina Cestari Biguetti,André Luis Shinohara,Geraldo Marco Rosa Junior,Geraldo Marco Rosa Junior,João Vitor Tadashi Cosin Shindo,Murilo Priori Alcalde,Murilo Priori Alcalde,Marco Antonio Hungaro Duarte,Daniel De Bortoli Teixeira,Rogério Leone Buchaim +15 more
TL;DR: It was concluded that the support system formed by the xenograft fibrin sealant associated with the photobiomodulation therapy protocol had a positive effect on the bone repair process.
Journal ArticleDOI
Photobiomodulation Therapy Associated with Heterologous Fibrin Biopolymer and Bovine Bone Matrix Helps to Reconstruct Long Bones
Marcelie Priscila de Oliveira Rosso,Aline Tiemi Oyadomari,Karina Torres Pomini,Bruna Botteon Della Coletta,João Vitor Tadashi Cosin Shindo,Rui Seabra Ferreira Junior,Benedito Barraviera,Claudia Vilalva Cassaro,Daniela Vieira Buchaim,Daniel De Bortoli Teixeira,Sandra Maria Barbalho,Murilo Priori Alcalde,Murilo Priori Alcalde,Marco Antonio Hungaro Duarte,Jesus Carlos Andreo,Rogério Leone Buchaim +15 more
TL;DR: It was concluded that the association of PBMT with HFB and BM has the potential to assist in the process of reconstructing bone defects in the tibia of rats.
Journal ArticleDOI
Low level laser therapy promotes bone regeneration by coupling angiogenesis and osteogenesis.
TL;DR: In this paper, the effects of low level laser therapy (LLLT) on vascularization and bone regeneration were evaluated in mice and human BMSCs and human umbilical vein endothelial cells.
References
More filters
Journal ArticleDOI
Stimulated Optical Radiation in Ruby
TL;DR: Schawlow and Townes as discussed by the authors proposed a technique for the generation of very monochromatic radiation in the infra-red optical region of the spectrum using an alkali vapour as the active medium.
Journal Article
Stimulated optical radiation in ruby
TL;DR: Schawlow and Townes as discussed by the authors proposed a technique for the generation of very monochromatic radiation in the infra-red optical region of the spectrum using an alkali vapour as the active medium.
Journal ArticleDOI
Fracture healing as a post‐natal developmental process: Molecular, spatial, and temporal aspects of its regulation
TL;DR: This Prospect Article will highlight a number of central biological processes that are believed to be crucial in the embryonic differentiation and growth of skeletal tissues and review the functional role of these processes during fracture healing.
Journal ArticleDOI
Fracture healing: mechanisms and interventions
TL;DR: The developmental progression of fracture healing at the tissue, cellular and molecular levels is reviewed and strategies for fracture treatment that have been tested in animal models and in clinical trials or case series are presented.
Journal ArticleDOI
Acceleration of tibial fracture-healing by non-invasive, low-intensity pulsed ultrasound.
TL;DR: This study confirms earlier animal and clinical studies that demonstrated the efficacy of low-intensity ultrasound stimulation in the acceleration of the normal fracture-repair process.
Related Papers (5)
Low-intensity pulsed ultrasound (LIPUS) for stimulation of bone healing - A narrative review.
Andrew Harrison,Volker Alt +1 more